Oracal

Perfect for sewing, quilting, scrapbooking, and a variety of other arts and crafts, digital cutting machines are changing the way people enjoy their favorite hobbies – and this complete how-to manual is here to help! With overviews on the top three brands – Cricut, Silhouette, and Brother – clear instructions for cutting different materials, technique tutorials, handy hacks, unique fabric-based step-by-step projects, and so much more Crafting with Digital Cutting Machines will help you make the most of your machine!

This book presents the selected proceedings of 2nd International Conference on Recent Advances in Manufacturing (RAM 2021). The book provides insights to current research trends and opportunities in modelling and optimization of manufacturing processes and systems. The topics covered include modelling analysis, computing and simulation, traditional and non-traditional optimization techniques, surface coating methods, additive manufacturing processes, CAD/CAM, robotics and automation, welding and joining processes, supply chain management and CAE and reverse engineering. This book will be a good reference for beginners, researchers and professionals interested in modelling and optimization related to manufacturing engineering and related fields.

DRUG TRANSPORTERS Drug transporter fundamentals and relevant principles and techniques, featuring new and expanded chapters Drug Transporters: Molecular Characterization and Role in Drug Disposition provides in-depth analysis of the conceptual evolution and technical development for studying drug transporters. Contributions by an international panel of leading researchers address advances in transporters as drug targets, transporters in pharmacotherapy, the impact of transporters on drug efficacy and safety, the development of sophisticated model systems and sensitive assay methods, and more. Divided into two parts, the book first provides a thorough overview of relevant drug transporters before detailing the principles of drug transport and associated techniques. The updated and expanded third edition includes new chapters on in vitro-in vivo scale-up of drug transport activities, the ontogeny of drug transporters, the application of physiologically-based pharmacokinetic and pharmacodynamic modeling, and the use of transporters as therapeutic targets for diseases. Reflects the current state of the field and offers perspectives on future directions Covers basic knowledge, clinical outcomes, and emerging discoveries in transporter science Provides up-to-date information on drug transporter families, mechanisms, and clinical implications Includes extensive references and numerous figures and tables throughout Understandable for novices while offering sufficient depth for more experienced researchers, Drug Transporters: Molecular Characterization and Role in Drug Disposition, Third Edition is an excellent textbook for pharmacological or physiological science courses in drug/membrane transport, and an invaluable reference for academic or industrial scientists working in the transporter field and related areas of drug metabolism, pharmacokinetics, and pharmacodynamics.

Color Chart celebrates a paradox: the lush beauty that results when contemporary artists assign colour decisions to chance, readymade source or arbitrary system. Midway through the 20th century, long-held convictions regarding the spiritual truth or scientific validity of particular colours gave way to an excitement about colour as a mass-produced and standardized commercial product. The Romantic quest for personal expression instead became Andy Warhol's 'I want to be a machine'; the artistry of mixing pigments was eclipsed by Frank Stella's 'Straight out of the can; it can't get better than that'. This book, and the exhibition it accompanies, is the first devoted to this pivotal transformation, and features work by some forty artists ranging from Ellsworth Kelly and Gerhard Richter to Sherrie Levine and Damien Hirst.

The ultimate Cricut how-to book that covers everything you need to know to purchase a Cricut and use it like a pro! Are you new to Cricut crafting? Returning after a hiatus and desperate for a refresher? Perhaps you're an old pro looking for brand-new ideas, tips, and tricks for your crafts? Look no further than The Unofficial Book of Cricut Crafts. Throughout the more than 300 pages of this book, author Crystal Allen will not only present you with craft ideas that embrace every awesome element of this popular cutting machine, but, perhaps most importantly, she'll start you at the very beginning of your Cricut journey with loads of information about the different Cricut machines (Cricut Explore Air 2, Cricut Maker, and Cricut Joy) so you can determine which is best for you before you buy. After you unbox your Cricut and have a general understanding of the parts of your machine, Crystal will teach you how to use Cricut Design Space and get images from Cricut Access, and then you'll be presented with projects that use the most popular materials your Cricut can cut. These include fabric (cotton, felt, and fleece); basswood and chipboard; leather; vinyl; paper; and heat transfer vinyl. Crystal even tackles infusible ink! Projects meant to inspire you will include step-by-step instructions and photos. They include: Personalized leather keychains Etched wine glasses Engraved quote bracelets Felt coffee cozies Paper luminaries Chalkboard signs Inspirational quote pillowcases Sleep masks Photo puzzles Leather headphone keepers Infusible Ink coasters A rag quilt and more! The Unofficial Book of Cricut Crafts is perfect for the first-time Cricut user, the small business owner who has been using Cricut for years, and everyone in between!