Oral Cancer Detection

This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

This book provides essential knowledge for creating treatment plans for adult dental patients. Treatment planning strategies are presented to help with balancing the ideal with the practical, with emphasis placed on the central role of the patient — whose needs should drive the treatment planning process. The focus is on planning of treatment, not on the comprehensive details of every treatment modality in dentistry. CD-ROM bound into book presents five cases of varying difficulty with interactive exercises that allow users to plan treatment. What's the Evidence? boxes link clinical decision-making and treatment planning strategies to current research. In Clinical Practice boxes highlight specific clinical situations faced by the general dentist. Review Questions and Suggested Projects, located at the end of each chapter, summarize and reinforce important concepts presented in the book. Key Terms and Glossary highlights the terms that are most important to the reader. Suggested Readings lists included at the end of most chapters provide supplemental resources. Chapter on Treatment Planning for Smokers and Patients with Oral Cancer addresses the dentist's role in managing patients with oral cancer, recognizing oral cancer and differential diagnosis of oral lesions, planning treatment for patients undergoing cancer therapy, and smoking cessation strategies. Chapter on Treatment Planning for the Special Care/Special Needs Patient examines the role of the general dentist in the management of patients with a variety of conditions including physical handicaps, mental handicaps, head trauma, hemophilia, and patients' needs before, during, or after major surgery. Chapter on Treatment Planning for the Alcohol and Substance Abuser discusses the challenges of treating this patient population, as well as how to recognize the problem, delivery of care, scope of treatment, and behavioral/compliance issues. Expanded content on Ethical and Legal Issues in Treatment Planning reflects new accreditation guidelines. Dental Team Focus boxes highlight the relevance of chapter content to the dental team. Ethics Topics boxes emphasize the ethical topics found within each chapter. International Tooth Numbering is listed alongside the U.S. tooth numbers in examples and illustrations.

Oral cancer is frequently diagnosed late, when the disease has advanced with lesions that are large and deeply invasive and with metastasis to regional lymph nodes, leading to increased mortality. Moreover, late diagnosis and treatment often result in considerable morbidity of oral and maxillofacial structures and poor appearance and function following therapy. This book provides head and neck oncologists, oral oncologists, oral and maxillofacial surgeons, medical oncologists, dentists and other members of dental teams furnishing supportive care with a systematic review of recent diagnostic and therapeutic advances in oral cancer. The various authoritative chapters are prepared by specialists who are active leaders in each basic and clinical field. All chapters address individual and collective issues that arise in managing oral cancer patients with difficult treatment problems and provide insight into the multiple valid management approaches available. The authors offer an extensive source of information about oral cancers and encourage the clinician to be flexible and innovative, giving physicians and medical personnel the background information to make the best, educated, responsible decisions for individual patients.

This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.

Oral Cancer: Diagnosis, Management, and Rehabilitation provides readers with a systematic review of the diagnostic and treatment principles that maximize the outcomes of patients who have been diagnosed with oral cancer. Written by authorities in the fields of head and neck surgical oncology, radiation oncology, reconstructive surgery, dentistry, and oral and maxillofacial surgery, this textbook provides clinicians with a unified management philosophy that is firmly based upon the best available evidence in the peer-reviewed literature. In-depth clinical reviews of preferred treatment approaches and reconstructive techniques for each oral mucosal site facilitate the development of effective treatment strategies that are tailored to the location and extent of the lesion. The book describes the interrelationship between the site of oral cancer involvement and its impact on outcomes, such as local-regional cancer control and quality of life following treatment. Features: Insightful reviews of controversial clinical issues, such as the management of early mandibular invasion and the clinically negative neck Step-by-step descriptions of surgical techniques which improve access to particular regions of the oral cavity, permit the resection of tumors with minimal morbidity, and result in optimal reconstructive outcomes Exhaustive coverage of topics that have heretofore received limited attention in textbooks devoted to oral cancer, including the evaluation and management of oral premalignant lesions, osseointegrated implantation and dental implant imaging, and orofacial pain Educational photographs and illustrations highlighting important teaching points and critical nuances in surgical technique Ideal for reading cover-to-cover, this book is both an indispensable reference for experienced clinicians and an essential educational tool for residents and other members of the multidisciplinary oral cancer team.

This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

Up to 70% of oral cancers are preceded by premalignant oral lesions, such as persistent red or white patches in the mouth. Survival rates for oral cancer can be improved through early detection. It is therefore essential that oral health professionals such as dentists, dental hygienists, dental therapists, and oral health therapists understand the importance of conducting a thorough oral screening examination for malignant and potentially malignant lesions as part of their routine clinical assessments, even in younger populations considered at lower risk for oral cancer. Key features of the book include: laser treatment techniques ,human genome sequencing, early detection and multidisciplinary approach ,management strategies and mechanisms of proliferation and energy metabolism in oral cancer.