Organ And Tissue Regeneration In Mammals

The main theme of this monograph - conditions of regenera tion of organs in mammals - reflects an area of increasing empha sis which permeates much current Soviet research on regeneration. The introduction of this theme goes back about 25 years, and empha sis on the influence of environmental conditions upon regenerative processes has fluctuated until the mid-1960s, when the viewpoints on this subject were established in much the same form as they are expressed in this book. For years, Russian regeneration research has been charac terized by the presence of several dominant and often conflicting schools of thought. Since an acquaintance with these makes the in terpretation of many of the theoretical implications of this book, particularly in the introductory and concluding chapters, consider ably clearer, those not familiar with the Russian literature might profit by reading my brief survey of this field (Carlson, B. M., 1968. Re generation research in the Soviet Union, Anat. Rec., 160:665-674).

Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).

This well-illustrated monograph is the first summary in English of L.V. Polezhaev's important but lesser known work on the regenerative phenomena in mammalian forms, conducted since World War II. During this period Soviet research underwent a pronounced shift in emphasis from basic biological studies based primarily upon amphibians to more practically oriented problems in mammalian systems. Polezhaev's experimentation underwent a corresponding shift, but the focus on restoration of lost regenerative capacity was retained since his earlier work, which is also reviewed here, on limb regeneration in frogs. Following a theoretical discussion, the monograph centers upon the author's most profound innovations: a successful method for producing bone to heal large skull defects, original research on heart regeneration, and trials in the restoration of limb regeneration following X-irradiation.

The main theme of this monograph - conditions of regenera tion of organs in mammals - reflects an area of increasing empha sis which permeates much current Soviet research on regeneration. The introduction of this theme goes back about 25 years, and empha sis on the influence of environmental conditions upon regenerative processes has fluctuated until the mid-1960s, when the viewpoints on this subject were established in much the same form as they are expressed in this book. For years, Russian regeneration research has been charac terized by the presence of several dominant and often conflicting schools of thought. Since an acquaintance with these makes the in terpretation of many of the theoretical implications of this book, particularly in the introductory and concluding chapters, consider ably clearer, those not familiar with the Russian literature might profit by reading my brief survey of this field (Carlson, B. M., 1968. Re generation research in the Soviet Union, Anat. Rec., 160:665-674).