Patient Specific Hemodynamic Computations Application To Personalized Diagnosis Of Cardiovascular Pathologies

Hemodynamic computations represent a state-of-the-art approach for patient-specific assessment of cardiovascular pathologies. The book presents the development of reduced-order multiscale hemodynamic models for coronary artery disease, aortic coarctation and whole body circulation, which can be applied in routine clinical settings for personalized diagnosis. Specific parameter estimation frameworks are introduced for calibrating the parameters of the models and high performance computing solutions are employed to reduce their execution time. The personalized computational models are validated against patient-specific measurements. The book is written for scientists in the field of biomedical engineering focusing on the cardiovascular system, as well as for research-oriented physicians in cardiology and industrial players in the field of healthcare technologies.

Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.

This book gathers selected papers presented at International Conference on IoT Based Control Networks and Intelligent Systems (ICICNIS 2022), organized by St. Joseph’s College of Engineering and Technology, Kottayam, Kerala, India, during July 1–2, 2022. The book covers state-of-the-art research insights on Internet of things (IoT) paradigm to access, manage, and control the objects/things/people working under various information systems and deployed under wide range of applications like smart cities, health care, industries, and smart homes.

This book touches upon various aspects of a very interesting, and growing in popularity category of models of dynamical systems. These are the so-called fractional-order systems. Such models are not only relevant for many fields of science and technology, but may also find numerous applications in other disciplines applying the mathematical modelling tools. Thus, the book is intended for a very wide audience of professionals who want to expand their knowledge of systems modelling and its applications. The book includes the selections of papers presented at the International Conference on Fractional Calculus and its Applications organized by the Warsaw University of Technology and was held online on 6–8 September 2021. The International Conference on Fractional Calculus and its Applications (ICFDA) has an almost twenty years history. It started in Bordeaux (France) in 2004, followed by Porto (Portugal) 2006, Istanbul (Turkey) 2008, Badajoz (Spain) 2010, Nanjing (China) 2012, Catania (Italy) 2014, Novi Sad (Serbia) 2016, Amman (Jordan) 2018. Next ICFDA was planned in 2020 in Warsaw (Poland), but COVID-19 pandemic shifted it to 6–8 September 2021. Hence, the organizers were forced to change the form of the conference to the online one. In the volume twenty eight high-quality research papers presented during the ICFDA 2021 eleven Regular Sessions with an additional online Discussion Session are presented. The presented papers are scientifically inspiring, leading to new fruitful ideas. They cover a very broad range of many disciplines. Nowadays, and especially in such a subject as fractional calculus, it is very difficult to assign papers to specific scientific areas. So, many of the papers included have an interdisciplinary character.

This book aims at informing on new trends, challenges and solutions, in the multidisciplinary field of biomedical engineering. It covers traditional biomedical engineering topics, as well as innovative applications such as artificial intelligence in health care, tissue engineering , neurotechnology and wearable devices. Further topics include mobile health and electroporation-based technologies, as well as new treatments in medicine. Gathering the proceedings of the 8th European Medical and Biological Engineering Conference (EMBEC 2020), held on November 29 - December 3, 2020, in Portorož, Slovenia, this book bridges fundamental and clinically-oriented research, emphasizing the role of education, translational research and commercialization of new ideas in biomedical engineering. It aims at inspiring and fostering communication and collaboration between engineers, physicists, biologists, physicians and other professionals dealing with cutting-edge themes in and advanced technologies serving the broad field of biomedical engineering.