Pediatric Drug Formulations 7th Edition

Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.

Since its first publication, this book has been the go-to guide for treating patients who require any of the 80% of medications not commercially available in appropriate forms or dosages for paediatric, geriatric, or special needs populations. Now even more comprehensive, the third edition provides the same evidence-based formulation in easy-to-follow "recipes" for 197 nonsterile formulations, 39 of which are new, and two of which have been updated for this edition. Each "recipe" includes ingredients; preparation details and instructions; storage conditions; special instructions; alternatives; expiration dates; references; and documented stability data. An invaluable resource for practitioners and compiled by experts in the field, this book provides the best guidance you can get for the care you want to give.

Only 20 percent of marketed medications have appropriate pediatric dosage information readily available. This lack of commercially available formulations challenges geriatric and special needs treatment as well. When seeking answers, pharmacy professionals turn to Extemporaneous Formulations for Pediatric, Geriatric, and Special Needs Patients, 2nd Edition. This one-of-a-kind resource offers information on: * Ingredients * Preparation details and instructions * Storage conditions * Special instructions * Alternatives * Expiration dates * Evidence-based monographs accompany helpful discussions of compounding, preparation methods, legal conditions, documentation, labeling and more. Get 35 Percent More Monographs If you are relying on the 2003 edition for your pediatric, geriatric or special-needs dosage information, it's time to update your library. This Second Edition features 160 total monographs, 35 percent more than the original.

This is an updated and expanded edition of the popular pocketbook aimed to serve the needs of medical students, resident doctors, general practioners, and consultant pediatricians. Several newer formulations including antiretroviral agents, antimalarias, and antibiatics have been Included. The standard or usual adult doses of most of the drugs are also provided. The book also serve as a ready-reckoner of drug dosages to young residents and practising pediatricians, and will intial confidence In their prescriptions and reduce the Incidence of avoidable side effects of drugs. It provides brief Information on the pharmacokinetics of drugs with emphasis on advantages and disadvantages of various routes of administration, drug absorption, distribution, bioavailabillty, tissue binding, half-life and metabolism and excretion. The drugs have been listed alphabetically dally dosages per unit body weight, frequency and route of administration. Important cautions, contraindications and adverse effects of selected drugs have been provided. Trade names of formulations from standard pharmaceutical companies along with their products and strengths are also given.

This book provides a comprehensive overview of all of the issues pharmacists serving pediatric patients must consider. Chapters relating to pharmacogenomics, medication error prevention, compounding, and government regulations are extremely informative.