Personalized Evolutionary And Ecological Dermatology

This book discusses the exciting potential for dermatology to embrace developments to enhance the profession’s valuable pattern recognition, diagnostic, and treatment skills. Personalized medicine (PM) and genomics are easily accessible and enable the customization of healthcare using molecular analysis to influence medical decisions, practices, and therapies for the individual patient. The evolution of the skin, and the manner in which dermatological conditions are described and managed, reveals the need to consider many aspects on a personal level. New research data are based on the use of evolutionary medicine and genomics to highlight how we can become more successful at finding the most efficacious types of antibiotic or therapy and dosage for a particular disease or pathogen and build a competitive edge by prevention and risk management against invasive viruses, bacteria, or wrongly administered drugs. As more is understood about what grows on us and how it all interacts, along with how the introduction of new antibiotics, biologics, and other therapies affect our skin’s ecological balance, this book aims to create a heightened sense of the importance and offerings of ecological dermatology.

This book is a quick reference guide to the new, more personalized approaches to the management of skin disorders that have emerged as a result of progress in our understanding of the genetic background and pathophysiology of skin diseases and the diversity of mechanisms underlying their clinical heterogeneity. A wide range of personalized and targeted therapies are described, including those for different skin cancers, chronic inflammatory skin diseases, and autoimmune diseases. In addition, readers will find that the book documents how research results in personalized medicine can be effectively transferred to dermatological practice and looks forward to future treatments that might be developed on the basis of recent research findings. The authors are all recognized experts in the field, and the text is presented in a reader-friendly format and well illustrated.

This volume brings together leading experts in comparative and evolutionary psychology. Top scholars summarize the histories and possible futures of their disciplines, and the contribution of each to illuminating the evolutionary forces that give rise to unique abilities in distantly and closely related species.

This volume synthesizes the theoretical and empirical work of leading scholars in the evolutionary sciences to produce an extensive and authoritative review of this literature.

This text is about the central role of evolution in shaping the nature and diversity of the living world. It describes the processes of natural selection, how adaptations arise, and how new species form, as well as summarizing the evidence for evolution

Full of practical advice, full-colour clinical photographs, and useful algorithms and management plans, Paediatric Dermatology is an indispensible and highly-accessible guide for all healthcare professionals faced with the assessment, diagnosis and treatment of children with skin diseases.

This book contains an overview of research on the interaction of biological and sociological processes. Issues explored include: the origins of social solidarity; religious beliefs; sex differences; gender inequality; human happiness; social stratification and inequality; identity, status, and other group processes; race, ethnicity, and discrimination; fertility and family processes; crime and deviance; cultural and social change.

Mental disorders arise from neural and psychological mechanisms that have been built and shaped by natural selection across our evolutionary history. Looking at psychopathology through the lens of evolution is the only way to understand the deeper nature of mental disorders and turn a mass of behavioral, genetic, and neurobiological findings into a coherent, theoretically grounded discipline. The rise of evolutionary psychopathology is part of an exciting scientific movement in psychology and medicine -- a movement that is fundamentally transforming the way we think about health and disease. Evolutionary Psychopathology takes steps toward a unified approach to psychopathology, using the concepts of life history theory -- a biological account of how individual differences in development, physiology and behavior arise from tradeoffs in survival and reproduction -- to build an integrative framework for mental disorders. This book reviews existing evolutionary models of specific conditions and connects them in a broader perspective, with the goal of explaining the large-scale patterns of risk and comorbidity that characterize psychopathology. Using the life history framework allows for a seamless integration of mental disorders with normative individual differences in personality and cognition, and offers new conceptual tools for the analysis of developmental, genetic, and neurobiological data. The concepts presented in Evolutionary Psychopathology are used to derive a new taxonomy of mental disorders, the Fast-Slow-Defense (FSD) model. The FSD model is the first classification system explicitly based on evolutionary concepts, a biologically grounded alternative to transdiagnostic models. The book reviews a wide range of common mental disorders, discusses their classification in the FSD model, and identifies functional subtypes within existing diagnostic categories.