Perspectives Of Pediatric Inflammatory Bowel Disease

Chronic inflammatory bowel disease (IBD) encompasses Crohn's disease, ulcerative colitis and indeterminate colitis. The distinct phenotype in pediatric and adolescent patients and the difference from adult IBD make early-onset IBD a unique subgroup requiring specific therapeutic considerations. In this book, leading experts from the USA, Europe and Israel present new data on the genetics, epidemiology, pathology and pathogenesis of pediatric IBD. Imaging and endoscopy in the diagnosis of IBD are also discussed. Extensive coverage is given to disease management, i.e. pharmacological, nutritional and surgical approaches, with special emphasis on growth failure and delayed puberty. The important topic of transition from pediatric to adult medical care is highlighted and a clinical and developmental timeline is proposed. Offering practical information on IBD in infants, toddlers, children, adolescents and young adults, this book is essential reading for gastroenterologists, in particular pediatric gastroenterologists and trainees, as well as general pediatricians and nutritionists.

Chronic inflammatory bowel disease (IBD) encompasses Crohn's disease, ulcerative colitis and indeterminate colitis. The distinct phenotype in pediatric and adolescent patients and the difference from adult IBD make early-onset IBD a unique subgroup requiring specific therapeutic considerations. In this book, leading experts from the USA, Europe and Israel present new data on the genetics, epidemiology, pathology and pathogenesis of pediatric IBD. Imaging and endoscopy in the diagnosis of IBD are also discussed. Extensive coverage is given to disease management, i.e. pharmacological, nutritional and surgical approaches, with special emphasis on growth failure and delayed puberty. The important topic of transition from pediatric to adult medical care is highlighted and a clinical and developmental timeline is proposed.Offering practical information on IBD in infants, toddlers, children, adolescents and young adults, this book is essential reading for gastroenterologists, in particular pediatric gastroenterologists and trainees, as well as general pediatricians and nutritionists.

Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.

This textbook focuses on the pediatric aspects of Inflammatory Bowel Disease (IBD). It covers diagnostic approaches, special nutrition, growth, and bone density, as well as psychosocial considerations that are specific to the young and may thus not exist in adults. Chapters discuss the full range of topics from IBD genetics right through to nutritional and growth aspects and condition management. The book features many visual aids as well as endoscopy and surgery images.

In this issue of Gastroenterology Clinics, guest editor Dr. Marla Dubinsky brings her considerable expertise to the topic of Pediatric Inflammatory Bowel Disease. Pediatric patients with IBD become adult patients with IBD, making it imperative that children receive early, effective intervention to optimize their growth and development, minimize disease complications, and support patients on their journey from childhood to adulthood. In this issue, top experts provide up-to-date information that helps provide an evidence-based approach for each patient. Contains 11 practice-oriented topics including optimizing the transition and transfer of care in pediatric IBD; building a self-management toolkit for pediatric IBD patients; choosing the right therapy at the right time for pediatric IBD: does sequence matter?; the state of clinical trials in pediatric IBD; the role of diet in pediatric IBD; and more. Provides in-depth clinical reviews on pediatric inflammatory bowel disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

These negative regulatory mechanisms of the intestinal immune system are disturbed in certain disease conditions, causing the immunocompetent cells to respond to food components and commensal bacteria by becoming activated and to overproduce inflammatory cytokines and chemokines. These disease conditions include food allergies, such as celiac disease, and the inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, although their exact etiological mechanisms remain to be revealed. --Book Jacket.

This book describes an up-to-date practical strategy for the use of endoscopy in the evaluation and management of pediatric patients with inflammatory bowel disease (IBD). All aspects of the role of endoscopy in Crohn's disease (CD) and ulcerative colitis (UC) - the two most common types of IBD - are addressed. Readers will find detailed information on its use in the initial diagnosis of IBD, differentiation between CD and UC, assessment of disease extent and activity, monitoring of response to therapy, and surveillance for cancer and dysplasia. Attention is drawn to specific clinical and endoscopic features of CD and UC in the pediatric age group that serve to illustrate why the child is not to be regarded merely as a small adult. Helpful information is also supplied on equipment, patient and parent preparation, and sedation. Endoscopy is considered the best means of obtaining a definite diagnosis in children who may have IBD, and this book will be of value to practitioners at all levels of experience.