Pharmacology Of Diabetes

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DIABETES DRUG NOTES Diabetes is becoming more common in both older and younger generations and in keeping with this escalation in cases, there are an ever increasing number of drugs and drug classes that are suitable to treat hyperglycaemia. In a unique blend of diabetes practice, clinical pharmacology, and cardiovascular medicine, Diabetes Drug Notes describes the principles of clinical pharmacology with regards to diabetes prescribing. Each drug class for the treatment of diabetes is covered in detail, along with the effect on the cardiovascular and renal systems caused by each drug. Building upon the success of their “Drug Notes” series for Practical Diabetes and their “Drugs for Diabetes” series in the British Journal of Cardiology, the team of experts focuses on the glycaemic management of type 1 and type 2 diabetes, with other effects of antidiabetic drugs covered as well. Diabetes Drug Notes also includes: Comprehensive and up-to-date coverage of the drugs for the glycaemic management of patients with type 1 or type 2 diabetes Expert reflection on prescribing considerations for special groups, as well as common pitfalls in prescribing Detailed case histories to illustrate relevant information Summaries of recent guidelines related to diabetic intervention Diabetes Drug Notes is a user-friendly guide for a general diabetes medical, nursing, and pharmacology readership, as well as those who support them.

This book is designed to be a ready reckoner on commonly used medications for the treatment of diabetes mellitus. Divided into 17 sections, topics include incretin-based therapies, insulin, chloroquine, metformin, colesevelam, drugs targeting renal excretion of glucose, management of dyslipidaemia, and more. The book concludes with discussion on associated comorbidities such as hypertension and diabetes in the elderly. Drug classes featured are all approved in-line with FDA (United States Food and Drug Administration) guidelines. Authored by recognised, US-based experts in the field, the comprehensive text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to pharmaceutical treatments for diabetes mellitus Features approved drugs in-line with FDA (United States Food and Drug Administration) guidelines Includes discussion on commonly associated comorbidities such as hypertension, and diabetes in the elderly Internationally recognised, US-based author team

Volume 27, the first thematic volume in the Series, provides an overview of present knowledge with regard to the pharmacological and clinical aspects of antidiabetic drugs. It aims to stimulate further consideration of possible concepts in the development of new antidiabetic drugs.

An expert guide to diabetes medications. Full details on each class of drugs and their role in treatment as well as fast references on everything from insulin analogs to the next metformin-glyburide combination. Eleven information-packed chapters also cover mixing and administering drugs, contraindications, and side effects. Each chapter’s Quick Reference section includes such areas as mechanism of action, pharmacokinetics, dosage forms and dose, and precautions/side effects. Topics Include: Sulfonylureas a-Glucosidase Inhibitors Glitazones Treatment of Hypertension in Patients with Diabetes Treatment of Hyperlipidemia in Patients with Diabetes Biguanides Overview of Medications Used to Treat Type 1 Diabetes

Type 2 diabetes (T2D), also known as non-insulin-dependent diabetes mellitus (NIDDM), is a condition in which cells fail to respond to insulin properly. As the disease progresses, the body does not produce enough insulin. There are several classes of anti-diabetic medications available, including the oral agent metformin. This medication is recommended as first-line treatment for T2D, except for those patients with severe kidney or liver problems. This book discusses the molecular mechanism, pharmacokinetics, and uses of metformin, as well as presents information on adverse drug reactions, drug interactions, and the potential use of metformin in tuberculosis.

Pharmacological and Molecular Perspectives on Diabetes is a compilation of reviews on clinical and scientific aspects of diabetes mellitus. It presents 11 contributions by eminent scholars that give the reader rational pharmacological and genetic perspectives of the disease and its treatment. The reviews approach diabetes from different angles, and highlight research that has been done to understand some questions about the molecular biology of diabetes in experimental settings. Topics of clinical significance such as the use of different hypoglycemic agents, and diabetic complications in clinical settings are also covered. Topics included in this book are: · Epigenetic alterations and type 2 diabetes mellitus · Responses to nutritional chromium supplements for type 2 diabetes mellitus · Endocrine role of osteocalcin in homeostatic regulation of glucose metabolism · Effect of diabetes on memory · Osteoarthritis in relation to type 2 diabetes mellitus: prevalence, etiology, symptoms and molecular mechanism · Infection of novel coronavirus in patients with diabetes mellitus · Role of an anti-inflammatory agent in the management of type 2 diabetes mellitus · Role of antidiabetic agents which helps regulates TCF7L2 variations in type 2 diabetes mellitus · Relationship between type 2 diabetes mellitus, PCOD and neurological disorders: role of antidiabetic drugs · Comparison of different types of insulin available for type 1 diabetes treatment · Circadian rhythm disruption: special reference to type 2 diabetes mellitus · Type 2 diabetes mellitus and its complications: pharmacogenetics based correlations and circulating microRNA as biomarkers Pharmacological and Molecular Perspectives on Diabetes should prove to be of interest to all pharmaceutical and molecular biology scientists who are involved in research in anti-diabetic drug design and discovery, and practicing endocrinologists who wish to keep abreast of recent developments in the field.

The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field.