Phenolic Acids

This book aims at introducing the non-specialist as well as the professionals in the fields of chemistry, biochemistry, biotechnology, food science and biomedical sciences into the biochemistry, applications and health benefits of an important group of natural products, phenolic acids. The book shows how phenolic acids display a potent antioxidant capacity and therefore health promoting effects and describe the phenolic acid composition in fruits and vegetables. The book also covers industrial applications related to phenolic acids. Furthermore, the book discusses the application of phenolic acids as food additives, since the preparation of foods with a high content of phenolic acids can lead to a reduction in the use of synthetic additives, resulting in healthier foods that can be included in the functional foods group. The book is of interest to specialists in the field but also to graduate or postgraduate students that are interested in this particular group of natural products.

Phenolic acids (PhAs), including hydroxybenzoic and cinnamic asids and their derivatives, are the products of secondary metabolism in plants and play important role in their growth and development. In this book, Chapter One discusses the phenolic acids during growth and development of xylem cells in Pinus sylvestris L. stems. Chapter Two evaluates the possible synergism or antagonism of several phenolic acids allowed to concomitantly react in an antioxidant capacity. Chapter Three evaluates the effect of different solvents on the extraction of major phenolic acids from aerial part of wild and greenhouse cultivated heather. Chapter Four focuses on quantification of the antioxidant activity on five varieties of mole produces in the Huichapan region in Mexico. Chapter Five examines antioxidant and cytotoxic activities of phenolic acids and their role in anticancer therapies. Chapter Six reviews the quantification and characterisation of phenolic acids in foods. Chapter Seven presents an overview on the physiological effects of phenolic acid in tea and coffee on human health.

This book aims at introducing the non-specialist as well as the professionals in the fields of chemistry, biochemistry, biotechnology, food science and biomedical sciences into the biochemistry, applications and health benefits of an important group of natural products, phenolic acids. The book shows how phenolic acids display a potent antioxidant capacity and therefore health promoting effects and describe the phenolic acid composition in fruits and vegetables. The book also covers industrial applications related to phenolic acids. Furthermore, the book discusses the application of phenolic acids as food additives, since the preparation of foods with a high content of phenolic acids can lead to a reduction in the use of synthetic additives, resulting in healthier foods that can be included in the functional foods group. The book is of interest to specialists in the field but also to graduate or postgraduate students that are interested in this particular group of natural products.

In an effort to implement conservation measures farmers have used a variety of production methods, including the use of reduced or zero tillage and cover crops. One benefit of these production methods has been early season weed control. The literature suggests that a variety of mechanisms may be involved, among them the allelopathic effects of phenolic acids. This retrospective analysis addresses the following: How likely are phenolic acid concentrations and environmental conditions in wheat no-till cropping systems for the inhibition of annual broadleaf weed emergence? and Do phenolic acids have a dominant role or are they just one component of a larger promoter/modifier/inhibitor complex? The book covers allelopathic plant-plant interactions, laboratory and field experiments, and future research. It uses a journal format, provides justifications for procedures used, if-then hypotheses, and cons and pros so that readers can reach their own conclusions.

Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids. Highlights fundamental concepts with advanced exploration of phenolic acids Provides in-depth coverage on the design and development of novel drugs from natural phenolic acids Reviews the changing role of phenolic acids

This book is mainly based on the latest research results and applications of phenolic and polyphenolic compounds. Phenolic compounds, ubiquitous in plants, are an essential part of the human diet and are of considerable interest due to their antioxidant properties and potential beneficial health effects. These compounds range structurally from a simple phenolic molecule to complex high-molecular-weight polymers. There is increasing evidence that consumption of a variety of phenolic compounds present in foods may lower the risk of health disorders because of their antioxidant activity. When added to foods, antioxidants control rancidity development, retard the formation of toxic oxidation products, maintain nutritional quality and extend the shelf-life of products. Due to safety concerns and limitation on the use of synthetic antioxidants, natural antioxidants obtained from edible materials, edible by-products and residual sources have been of increasing interest. This contribution summarizes both the synthetic and natural phenolic antioxidants, emphasizing their mode of action, health effects, degradation products and toxicology. In addition, sources of phenolic antioxidants are discussed in detail.

This book is a printed edition of the Special Issue "Phenolic Compounds in Fruit Beverages" that was published in Beverages

This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.