Phenotypic Characterization Genetics And Genomics Of Livestock In Low Input Systems

These guidelines are part of a series of publications produced by FAO to support countries in the implementation of the Global Plan of Action for Animal Genetic Resources.

Over the past 15 years, there have been rapid and ever-increasing advances in science and technology, institutional and human capacities and infrastructure in the field of gene sequencing and in the associated bioinformatics (the application of information technology and computer science to the field of molecular biology) and high-performance computing. This publication provides an update on recent developments in biotechnologies relevant to the characterization, sustainable use and conservation of genetic resources for food and agriculture.

This publication provides an update on the current status of gene maps in different livestock and pet/companion animal species. The findings summarized in species specific commentaries and original articles testify the rapid advances made in the field of animal genomics. Of significant interest is the fact that current investigations are providing headways for two important and exciting research fronts: targeted high-resolution mapping leading to the application of genomic information in addressing questions of economic and biological significance in animals, and the initiation of whole genome sequencing projects for some of the animal species. Like in humans and mice, this will set the stage for a new level of research and real time complex analysis of the genomes of these species. Animal Genomics signifies the beginning of a new era in this field and celebrates the achievements of the past 20 years of genomics research. It will be of special interest to researchers involved in genome analysis - both gross chromosomal as well as molecular - in various animal species, and to comparative and evolutionary geneticists.

Animal genetic resource diversity underpins the supply livestock products and services across a wide range of production environments. It promotes resilience and serves as a basis for adapting livestock management to changing conditions. It is vital to livelihoods of many of the world’s poor people. It can contribute to the delivery of ecosystem services such as landscape management and the maintenance of wildlife habitats. However, it is often undervalued, underused and under threat. This report updates the global assessment provided in the first report on The State of the World’s Animal Genetic Resources for Food and Agriculture, published in 2007. It focuses particularly on changes that have occurred during the period since the first report was published. It serves as a basis for a review, and potential update, of the Global Plan of Action for Animal Genetic Resources, which since 2007 has provided an agreed international framework for the management of livestock biodiversity. Drawing on 129 country reports, it presents an analysis of the state of livestock diversity, the influence of livestock-sector trends on the management of animal genetic resources, the state of capacity to manage animal genetic resources, including legal and policy frameworks, and the state of the art in tools and methods for characterization, valuation, use, development and conservation.

The FAO international symposium on “The role of agricultural biotechnologies in sustainable food systems and nutrition” took place from 15 to 17 February 2016 at FAO headquarters, Rome. Over 400 people attended, including 230 delegates from 75 member countries and the European Union, as well as representatives of intergovernmental organizations, private sector entities, civil society organizations, academia/research organizations and producer organizations/cooperatives. The symposium encompassed the crop, livestock, forestry and fishery sectors and was organized around three main themes: i) climate change; ii) sustainable food systems and nutrition; and iii) people, policies, institutions and communities. The proceedings provide the main highlights of the symposium which covered a broad range of biotechnologies, from low-tech approaches such as those involving use of microbial fermentation processes, biofertilizers, biopesticides and artificial insemination, to high-tech approaches suc h as those involving advanced DNA-based methodologies and genetically modified organisms. The full report has been divided into sections and individual chapters for ease of downloading: Introduction to the Proceedings Chapter 1. Opening plenary session Chapter 2. High-level ministerial session Chapter 3. Parallel sessions: Climate change Chapter 4. Parallel sessions: Sustainable food systems and nutrition Chapter 5. Parallel sessions: People, policies, institutions and communities Chapter 6. Student interactive session: Bringing fresh perspectives Chapter 7. Side events: Reports Chapter 8. Final plenary session For more information, visit the webpage http://www.fao.org/about/meetings/agribiotechs-symposium/en/.

The history of livestock started with the domestication of their wild ancestors: a restricted number of species allowed to be tamed and entered a symbiotic relationship with humans. In exchange for food, shelter and protection, they provided us with meat, eggs, hides, wool and draught power, thus contributing considerably to our economic and cultural development. Depending on the species, domestication took place in different areas and periods. After domestication, livestock spread over all inhabited regions of the earth, accompanying human migrations and becoming also trade objects. This required an adaptation to different climates and varying styles of husbandry and resulted in an enormous phenotypic diversity. Approximately 200 years ago, the situation started to change with the rise of the concept of breed. Animals were selected for the same visible characteristics, and crossing with different phenotypes was reduced. This resulted in the formation of different breeds, mostly genetically isolated from other populations. A few decades ago, selection pressure was increased again with intensive production focusing on a limited range of types and a subsequent loss of genetic diversity. For short-term economic reasons, farmers have abandoned traditional breeds. As a consequence, during the 20th century, at least 28% of farm animal breeds became extinct, rare or endangered. The situation is alarming in developing countries, where native breeds adapted to local environments and diseases are being replaced by industrial breeds. In the most marginal areas, farm animals are considered to be essential for viable land use and, in the developing world, a major pathway out of poverty. Historic documentation from the period before the breed formation is scarce. Thus, reconstruction of the history of livestock populations depends on archaeological, archeo-zoological and DNA analysis of extant populations. Scientific research into genetic diversity takes advantage of the rapid advances in molecular genetics. Studies of mitochondrial DNA, microsatellite DNA profiling and Y-chromosomes have revealed details on the process of domestication, on the diversity retained by breeds and on relationships between breeds. However, we only see a small part of the genetic information and the advent of new technologies is most timely in order to answer many essential questions. High-throughput single-nucleotide polymorphism genotyping is about to be available for all major farm animal species. The recent development of sequencing techniques calls for new methods of data management and analysis and for new ideas for the extraction of information. To make sense of this information in practical conditions, integration of geo-environmental and socio-economic data are key elements. The study and management of farm animal genomic resources (FAnGR) is indeed a major multidisciplinary issue. The goal of the present Research Topic was to collect contributions of high scientific quality relevant to biodiversity management, and applying new methods to either new genomic and bioinformatics approaches for characterization of FAnGR, to the development of FAnGR conservation methods applied ex-situ and in-situ, to socio-economic aspects of FAnGR conservation, to transfer of lessons between wildlife and livestock biodiversity conservation, and to the contribution of FAnGR to a transition in agriculture (FAnGR and agro-ecology).