Place Randomized Trials
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Field Trials of Health Interventions
Author | : Peter G. Smith,R. H. Morrow,Richard H. Morrow,David A. Ross |
Publsiher | : Oxford University Press, USA |
Total Pages | : 479 |
Release | : 2015 |
Genre | : Medical |
ISBN | : 9780198732860 |
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"IEA, International Epidemiological Association, Welcome Trust."
Cluster Randomised Trials
Author | : Richard J. Hayes,Lawrence H. Moulton |
Publsiher | : CRC Press |
Total Pages | : 466 |
Release | : 2017-07-06 |
Genre | : Mathematics |
ISBN | : 9781315353234 |
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Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects. In the time since the publication of the first edition, the use of cluster randomised trials (CRTs) has increased substantially, which is reflected in the updates to this edition. There are greatly expanded sections on randomisation, sample size estimation, and alternative designs, including new material on stepped wedge designs. There is a new section on handling ordinal outcome data, and an appendix with descriptions and/or generating code of the example data sets. Although the book mainly focuses on medical and public health applications, it shows that the rigorous evidence of intervention effects provided by CRTs has the potential to inform public policy in a wide range of other areas. The book encourages readers to apply the methods to their own trials, reproduce the analyses presented, and explore alternative approaches.
Introduction to Randomized Controlled Clinical Trials
Author | : John N.S. Matthews |
Publsiher | : CRC Press |
Total Pages | : 304 |
Release | : 2006-06-26 |
Genre | : Mathematics |
ISBN | : 9781420011302 |
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Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification, design, and analysis. This second edition of Introduction to Randomized Controlled Clinical Trials prov
Randomization in Clinical Trials
Author | : William F. Rosenberger,John M. Lachin |
Publsiher | : John Wiley & Sons |
Total Pages | : 284 |
Release | : 2015-11-23 |
Genre | : Mathematics |
ISBN | : 9781118742242 |
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Praise for the First Edition “All medical statisticians involved in clinical trials should read this book…” - Controlled Clinical Trials Featuring a unique combination of the applied aspects of randomization in clinical trials with a nonparametric approach to inference, Randomization in Clinical Trials: Theory and Practice, Second Edition is the go-to guide for biostatisticians and pharmaceutical industry statisticians. Randomization in Clinical Trials: Theory and Practice, Second Edition features: Discussions on current philosophies, controversies, and new developments in the increasingly important role of randomization techniques in clinical trials A new chapter on covariate-adaptive randomization, including minimization techniques and inference New developments in restricted randomization and an increased focus on computation of randomization tests as opposed to the asymptotic theory of randomization tests Plenty of problem sets, theoretical exercises, and short computer simulations using SAS® to facilitate classroom teaching, simplify the mathematics, and ease readers’ understanding Randomization in Clinical Trials: Theory and Practice, Second Edition is an excellent reference for researchers as well as applied statisticians and biostatisticians. The Second Edition is also an ideal textbook for upper-undergraduate and graduate-level courses in biostatistics and applied statistics. William F. Rosenberger, PhD, is University Professor and Chairman of the Department of Statistics at George Mason University. He is a Fellow of the American Statistical Association and the Institute of Mathematical Statistics, and author of over 80 refereed journal articles, as well as The Theory of Response-Adaptive Randomization in Clinical Trials, also published by Wiley. John M. Lachin, ScD, is Research Professor in the Department of Epidemiology and Biostatistics as well as in the Department of Statistics at The George Washington University. A Fellow of the American Statistical Association and the Society for Clinical Trials, Dr. Lachin is actively involved in coordinating center activities for clinical trials of diabetes. He is the author of Biostatistical Methods: The Assessment of Relative Risks, Second Edition, also published by Wiley.
Place Randomized Trials
Author | : Robert F. Boruch |
Publsiher | : Wm. B. Eerdmans Publishing |
Total Pages | : 296 |
Release | : 2005-05 |
Genre | : Political Science |
ISBN | : 1412925827 |
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The phrase "evidence-based policy" is frequently used, but it's crucial that such claims are scrutinized and validated. When the data on social and behavioral interventions are presented, high-quality evidence must be clearly defined and the methodology behind such studies held to rigorous standards. Both the Cochrane Collaboration –focusing on healthcare – and the international Campbell Collaboration – concentrating on criminal justice, education, and social services – were created to develop, maintain and improve detailed guidelines for producing high-quality systematic reviews. And both organizations emphasize randomized controlled trials to evaluate the effectiveness of various interventions. As a springboard from the Campbell Collaboration initiative and supported by the Rockefeller Foundation, this special issue of The Annals includes a thorough review of randomized tests across a variety of studies. Exploring significant dimensions of place randomized trials (also called cluster randomized trials or group randomized trials), these papers shed light on recent efforts to enhance the quality of designing such trials as well as on results reporting. The research topics included in this volume are diverse. Taken together, these papers offer important insight into the nuts and bolts of conducting randomized trials: the significance of place in trials; how such studies are initiated; the incentives and justifications needed by participants; how to overcome challenges of implementation; and where to find out what studies have already been conducted or are currently underway. While providing far-reaching insight into the topic of randomized testing, these papers also identify new issues and key questions to be further addressed in future research. Scholars and policymakers alike will find this collection of rigorous research essential in understanding the implications of current evidence-based policies as well as a guidepost for designing and conducting new studies.
Designing Randomised Trials in Health Education and the Social Sciences
Author | : D. Torgerson |
Publsiher | : Springer |
Total Pages | : 226 |
Release | : 2008-03-13 |
Genre | : Social Science |
ISBN | : 9780230583993 |
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The book focuses on the design of rigorous trials rather than their statistical underpinnings, with chapters on: pragmatic designs; placebo designs; preference approaches; unequal allocation; economics; analytical approaches; randomization methods. It also includes a detailed description of randomization procedures and different trial designs.
Taming Randomized Controlled Trials in Education
Author | : Keith Morrison |
Publsiher | : Routledge |
Total Pages | : 203 |
Release | : 2020-07-07 |
Genre | : Computers |
ISBN | : 9781000089929 |
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There is a recent surge in the use of randomized controlled trials (RCTs) within education globally, with disproportionate claims being made about what they show, ‘what works’, and what constitutes the best ‘evidence’. Drawing on up-to-date scholarship from across the world, Taming Randomized Controlled Trials in Education critically addresses the increased use of RCTs in education, exploring their benefits, limits and cautions, and ultimately questioning the prominence given to them. While acknowledging that randomized controlled trials do have some place in education, the book nevertheless argues that this place should be limited. Drawing together all arguments for and against RCTs in a comprehensive and easily accessible single volume, the book also adds new perspectives and insights to the conversation; crucially, the book considers the limits of their usefulness and applicability in education, raising a range of largely unexplored concerns about their use. Chapters include discussions on: The impact of complexity theory and chaos theory. Design issues and sampling in randomized controlled trials. Learning from clinical trials. Data analysis in randomized controlled trials. Reporting, evaluating and generalizing from randomized controlled trials. Considering key issues in understanding and interrogating research evidence, this book is ideal reading for all students on Research Methods modules, as well as those interested in undertaking and reviewing research in the field of education.
Design and Analysis of Group randomized Trials
Author | : David M. Murray |
Publsiher | : Monographs in Epidemiology and |
Total Pages | : 481 |
Release | : 1998 |
Genre | : Medical |
ISBN | : 9780195120363 |
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Community or group-randomized trials, which are usually done to evaluate the effect of health promotion effors. It reviews the underlying issues, describes the most widely used research design, and presents the many approaches to analysis that are now available.