Point Of Care Biosensors For Infectious Diseases

Point-of-Care Biosensors for Infectious Diseases Comprehensive resource covering key developments in biosensor-based diagnostics for infectious diseases With its overview of currently available technologies, Point-of-Care Biosensors for Infectious Diseases serves as a starting point for the successful development and application of pathogen biosensors in a point-of-care setting. Here, expert authors review current challenges in pathogen detection and the selection of suitable biomarkers, detail currently available biosensor platforms including electrochemical, piezoelectric, magnetic, and optical sensors, and cover technology development for point-of-care biosensors for viral, bacterial, and parasitic infections. Point-of-Care Biosensors for Infectious Diseases covers key topics such as: Fundamentals of biosensor detection, with a focus on optical and electrochemical techniques Organic and inorganic based nanomaterials for healthcare diagnostics Strategies for miniaturizing biosensor devices, and state-of-the-art integrated sensing platforms Latest trends in point-of-care biosensing systems to detect, diagnose, and monitor infectious diseases Providing comprehensive coverage of the subject, Point-of-Care Biosensors for Infectious Diseases is an excellent reference for all developers, researchers, and technology managers in the areas of molecular diagnosis, infectious diseases, biosensors, and related fields.

Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications Includes contributions from leading international researchers with extensive experience in developing medical biosensors Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care

Biosensors for Emerging and Re-Emerging Infectious Diseases provides a review of how cornerstone optical, electronic, nanomaterial and data processing technologies can address detection issues occurring in a pandemic event. This book gives insights into the fundamental physical, chemical and biological mechanisms needed for such a type of detection. The content covers potential biomarkers which can be used for the infectious disease diagnostic, helping readers find the appropriate approach for the diagnosis of infectious diseases. It presents a novel approach to transferring the sensing platform from lab to application in clinics and to point of care detection. The book then moves on to discuss the function and efficiency of the biosensing platform in early diagnosis of infectious diseases compared to the standard methods. The required time, the technician skills and the steps which must be performed are other key factors of the biosensing platform which are well explained. Covers applications of biosensors in diagnostics and detection of infection, and in the application of new materials in biosensor development Presents nano-biosensor based point-of-care technologies Introduces readers to the fundamentals of biosensors for infectious diseases

Point-of-Care Biosensors for Infectious Diseases Comprehensive resource covering key developments in biosensor-based diagnostics for infectious diseases With its overview of currently available technologies, Point-of-Care Biosensors for Infectious Diseases serves as a starting point for the successful development and application of pathogen biosensors in a point-of-care setting. Here, expert authors review current challenges in pathogen detection and the selection of suitable biomarkers, detail currently available biosensor platforms including electrochemical, piezoelectric, magnetic, and optical sensors, and cover technology development for point-of-care biosensors for viral, bacterial, and parasitic infections. Point-of-Care Biosensors for Infectious Diseases covers key topics such as: Fundamentals of biosensor detection, with a focus on optical and electrochemical techniques Organic and inorganic based nanomaterials for healthcare diagnostics Strategies for miniaturizing biosensor devices, and state-of-the-art integrated sensing platforms Latest trends in point-of-care biosensing systems to detect, diagnose, and monitor infectious diseases Providing comprehensive coverage of the subject, Point-of-Care Biosensors for Infectious Diseases is an excellent reference for all developers, researchers, and technology managers in the areas of molecular diagnosis, infectious diseases, biosensors, and related fields.

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2. In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization. Deals with biosensors-based approaches that could be exploited to design and develop high throughput, rapid and cost-effective diagnostics technologies for the early detection of viral infections Illustrates the development of multiplexed, miniaturized analytical systems for point-of-care applications Provides information about fabrication protocols for various biosensor based diagnostic approaches that could be directly implemented to develop a novel biosensor Includes the past, present and future status of biosensors, along with information about biosensors currently under clinical trials

Point-of-care testing devices for early detection, screening and diagnosis have been proven to significantly improve patient survival rates and quality of life, as well as to significantly reduce the cost and complexity of disease treatment. Providing a timely update on the current understanding of paper-based biosensors, this book aims to deal with the current state-of-the-art of paper-based biosensors technology and addresses its future prospects for the detection of infectious diseases, with particular relevance and applications for low-income and developing countries. This book focuses on the design and fabrication strategies of paper-based devices for the detection of various biomolecules in biomedicine. This comprehensive research and reference text would be suitable for researchers, scholars, and manufacturers in multiple disciplines, such as medical device design.

This book comprehensively reviews various nanodiagnostic approaches for the detection of bacterial pathogens. The initial chapter of the book discusses receptors present on bacterial cell surfaces that can be targeted for diagnostic applications. The book then presents different fluorescent nanoparticle systems that are used for bacterial detection. Further, it covers surface plasmon resonance (SPR), ELISA, and QCM-based nanosensors to detect pathogenic bacteria. It examines different nanosensors used for the microfluidic-based detection of bacterial pathogens, including microfluidic paper-based analytical devices (μPADs), lateral flow devices, and miniaturized PCR devices. The book also covers the current electrochemical, voltammetric, and amperometric nanosensors-based microorganism recognition approaches. Lastly, the book summarizes the current challenges and the futuristic application of nanosensors to detect bacterial pathogens. This book is an invaluable resource for all medical laboratories and clinical institutions dealing with infectious diseases.

Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient’s life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer