Polyphenolics

Polyphenols in Plants assists plant scientists and dietary supplement producers in assessing polyphenol content and factors affecting their composition. It also aids in selecting sources and regulating environmental conditions affecting yield for more consistent and function dietary supplements. Polyphenols play key roles in the growth, regulation and structure of plants and vary widely within different plants. Stress, growth conditions and plant species modify polyphenol structure and content. This book describes techniques to identify, isolate and characterize polyphenols, taking mammalian toxicology into account as well. Defines conditions of growth affecting the polyphenol levels Describes assay and instrumentation techniques critical to identifying and defining polyphenols, critical to researchers and business development Documents how some polyphenols are dangerous to consume, important to dietary supplement industry, government regulators and lay public users

This book describes the scientific basis for the action of plant polyphenols in a wide range of phenomena.

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

This Special Issue is focused on natural polyphenols and their synthetic bioactive analogues. It is composed of one review on aza- and azo-stilbenes as bioisosteric analogs of the stilbenoid resveratrol and four original articles, including studies on synthetic (bisphenol neolignans inspired by honokiol, multicomponent synthesis of polyphenols), and natural polyphenols (polyphenols from Tamarix ramosissima and Melanoleuca styphelioides) as antiproliferative, anti-Alzheimer’s, antioxidant, antimicrobial, or anti-inflammatory agents.

"Polyphenolics are compounds found in plants, such as phenolic acid and flavonoids, that have positive effects on human health and help fight disease. As such, studies of these compounds are valuable for those looking to improve their own health or the health of others. Chapter One addresses the role that polyphenolics plays in the assessment of food integrity and authenticity. Chapter Two studies the potential of regular long-term consumption of various fruit species for reducing diabetes mellitus. Chapter Three provides a platform for the selection of solvent for extraction, column and mobile phase for better separation of polyphenol compounds. Chapter Four presents extraction with subcritical water as a technique for polyphenol isolation. Lastly, Chapter Five attempts to bridge the gap between the different ethnomedical and folklore claims of utilization of Amaranth germplasms against degenerative diseases with matching polyphenol-based chemical data having antioxidant and anti-inflammatory properties"--

Polyphenolic compounds are part of a division of secondary metabolites with high antioxidant capacity, found naturally in most edible and inedible plants. These compounds are responsible for pigmentation and plants defense of pathogens agents. Its molecular structure includes phenolic hydroxyl groups and aromatic rings. Polyphenols are increasingly studied because of the benefits to human health, introducing the ability to eliminate free radicals generated by oxidation, reducing risk of cancer, anti-aging, anti-diabetic, among others. This book provides new research on food sources of polyphenolic compounds, and their biochemistry and health benefits.