Principles Of Endocrinology And Hormone Action

This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

Established as the foremost text in the field, Principles and Practice of Endocrinology and Metabolism is now in its thoroughly revised, updated Third Edition. This practical, clinically relevant, and comprehensive text covers the entire field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and much more. The Third Edition contains new chapters reflecting the latest advances and features expanded coverage of genetics and the endocrinology of sepsis. More than 1,400 illustrations complement the text. A drug formulary appears at the back of the book.

Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, this new edition succinctly summarizes in 450 pages the latest findings on hormone secretion and hormone action, as well as all the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in man and the lower species, and the mechanisms subserving hormone secretion.

Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The principles of endocrinology and metabolism clearly and simply explained on a system-by-system, organ-by-organ basis ESSENTIAL FOR USMLE® STEP 1 REVIEW! A Doody’s Core Title for 2020! Applauded by medical students for its clarity, comprehensiveness, and portability, Endocrine Physiology, Fifth Edition delivers unmatched coverage of the fundamental concepts of hormone biological actions. These concepts provide a solid foundation for first-and-second year medical students to understand the physiologic mechanisms involved in neuroendocrine regulation of organ function. With its emphasis on must-know principles, Endocrine Physiology is essential for residents and fellows, and is the single-best endocrine review available for the USMLE® Step 1. Here’s why this is essential for USMLE® Step 1 review: •Informative first chapter describes the organization of the endocrine system, as well as general concepts of hormone production and release, transport and metabolic rate, and cellular mechanisms of action •Boxed case studies help you apply principles to real-world clinical situations •Each chapter includes bulleted Objectives, Key Concepts, Study Questions, Suggested Readings, and diagrams encapsulating key concepts If you’ve been looking for a student-tested, basic yet comprehensive review of endocrinology and metabolism, your search ends here.

The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today’s systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout. Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation. The Endocrine System provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases. Introduction Receptors and Hormone Action The Hypothalamus and Pituitary Part I: The Hypothalamus and Posterior Pituitary4 The Hypothalamus and Pituitary Part II: The Anterior Pituitary The Adrenal Glands Part I: The Adrenal Medulla The Adrenal Glands Part II: The Adrenal Cortex The Thyroid Gland Hormonal Control of Reproduction Part I: Male Reproductive System Hormonal Control of Reproduction Part II: Female Reproductive System Hormonal Control of Reproduction Part III: Development and Fertility Insulin and the Regulation of Plasma Glucose Hormonal Regulation of Plasma Calcium and Calcium Metabolism Miscellaneous Hormones Systems of the Body Series: The Renal System The Musculoskeletal System The Nervous System The Digestive System The Endocrine System The Respiratory System The Cardiovascular System

Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, this new edition succinctly summarizes in 450 pages the latest findings on hormone secretion and hormone action, as well as all the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in man and the lower species, and the mechanisms subserving hormone secretion.

This concise overview of hormone biological actions introduces basic science principles and their relevance in the clinical expression of disease. Each chapter incorporates a wealth of pedagogical aids including: study questions, learning objectives, and clinical examples.