Procedures Of Resistance

The equipment and procedures used at NBS for the precise measurement of d-c resistance are explained in detail. The specific application of these procedures to the calibration of bridges and potentiometers is explained. It is expected that this paper will be of considerable help to the many company and governmental standardizing laboratories now being established.

Resistance to chemotherapy, and especially multi-drug resistance, represents a significant barrier to the successful treatment of cancer. This multi-author volume brings together a wide range of up-to-date reviews on different aspects of our knowledge of drug-resistance mechanisms, written by experts in the different areas. Particular attention is paid to recently discovered mechanisms relating to oncogene expression and in particular to proteins involved in regulation and execution of apoptosis. Other important topics covered include DNA repair, topoisomerases, cell cycle control, oxygenation and vascularisation of tumours, LRP, intermediate filament proteins and low-level resistance. Recent developments in understanding the role of efflux pumps (P-170, MRP) in multi-drug resistance are also reviewed. This book will be useful to clinicians and scientists working in the areas of chemotherapy, drug resistance, DNA repair and apoptosis research.

A collaborative effort of 150+ clinical microbiologists, medical laboratory technologists, and laboratory supervisors. • Provides step-by-step protocols and descriptions to enable clinical microbiologists and laboratory staff personnel to perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation. • Emphasizes areas such as molecular approaches, bioterrorism, safety, and epidemiology/infection control in medical facilities. • Includes procedures that are formatted to adhere to the GP02-5A (2006) document of the National Committee for Clinical Laboratory Standards/Clinical and Laboratory Standards Institute (NCCLS/CLSI).

The 4th edition of Viral Hepatitis covers comprehensively the entire complex field of infections caused by all of the different hepatitis viruses, which affect many millions of people throughout the world with considerable morbidity and mortality. Howard Thomas and Arie Zuckerman are joined by Anna Lok from the USA and Stephen Locarnini from Australia as Editors. They have recruited leading researchers and physicians from many countries, who have produced an authoritative account of current knowledge and research on this important infection, including new insights into immune response to HBV and HCV. The result is a comprehensive account on all aspects of viral hepatitis, including rapid advances in the diagnosis, management, treatment and prevention of a complex infection, which in the case of hepatitis B, C and D may lead to severe complications including chronic hepatitis, cirrhosis and hepatocellular carcinoma. The latest edition of Viral Hepatitis offers an essential resource of current information for hepatologists, gastroenterologists, infectious diseases specialists and other clinicians, researchers, public health physicians and National and International Health Authorities.

Based on a symposium sponsored by the Board on Agriculture, this comprehensive book explores the problem of pesticide resistance; suggests new approaches to monitor, control, or prevent resistance; and identifies the changes in public policy necessary to protect crops and human health from the ravages of pests. The volume synthesizes the most recent information from a wide range of disciplines, including entomology, genetics, plant pathology, biochemistry, economics, and public policy. It also suggests research avenues that would indicate how to counter future problems. A glossary provides the reader with additional guidance.