Procurement And Transplantation Of Abdominal Organs In Clinical Practice

This practical guide provides a full but concise account of the organ donation and transplantation process, from the management of the donor and organ preservation to perioperative management and surgical techniques. Readers will learn about various aspects of multi-organ retrieval such as different types of donors and evaluation of organ donors, as well as the retrieval process itself and ethical aspects of transplantation. Written in a consistent format, each of the themed parts examines the different types of solid organ transplantation, namely kindey, pancreas and liver. Each part discusses the indications for transplantation, organ allocation, surgical technique, post-operative management outcomes and professional skills for the surgeon. This is an essential guide for the transplant surgeon offering a unique summary of the critical issues in abdominal organ transplantation.

This practical guide provides a full but concise account of the organ donation and transplantation process, from the management of the donor and organ preservation to perioperative management and surgical techniques. Readers will learn about various aspects of multi-organ retrieval such as different types of donors and evaluation of organ donors, as well as the retrieval process itself and ethical aspects of transplantation. Written in a consistent format, each of the themed parts examines the different types of solid organ transplantation, namely kindey, pancreas and liver. Each part discusses the indications for transplantation, organ allocation, surgical technique, post-operative management outcomes and professional skills for the surgeon. This is an essential guide for the transplant surgeon offering a unique summary of the critical issues in abdominal organ transplantation.

The book encompasses Dr Baranski’s 20 year experience in the field of abdominal organ donation. It is a step-by-step guide with photographs and drawings with clear explanations highlighting pitfalls. The book quickly and easily guides the reader through the difficult steps during organ procurement. It is mainly illustration-based, without much text, and covers surgical technical mistakes and organ damage.

This well-illustrated handbook provides answers to important questions that may arise during the retrieval of multiple organs for transplantation and offers step-by-step descriptions of current surgical techniques for procurement of the various thoracic and abdominal organs, including heart, lung, liver, intestine, pancreas, and kidney. The coverage includes detailed instruction on liver splitting techniques and on living donor liver hepatectomies and laparoscopic and robot-assisted nephrectomy for transplantation. In addition, guidance is provided on preoperative evaluation for multiorgan donation, contraindications, management for organ retrieval in deceased donors, and organ preservation. The advice offered and the questions addressed will be of relevance not only to transplant surgeons, trainees, and fellows but also to all other professionals involved in organ transplantation, including nursing staff in intensive care units and emergency rooms.

Advances in the science of immunology have improved the success rate of organ transplantations since the mid twentieth century. Organ transplantation is now a lifesaving medical procedure for thousands of patients around the world with end-organ diseases. The lifesaving potential of transplantation has been limited by the number and quality of appropriate organ donors. The evolution of brain death criteria by the Harvard Ad-Hoc Committee Report has opened the door to understanding the importance of medical, legal and ethical challenges of organ donation in support of the growth of the transplant science. The possibility of organ donation from living donors has enhanced organ availability for patients with kidney failure. Modern inotropes and immunosuppression regimens have been critical to the success of other organ transplant procedures. However, the cornerstone of successful transplantation continues to be the appropriate selection, evaluation, preservation of organ tissues and the successful surgical procurement process to mitigate the impact of tissue ischemia and reperfusion. In this textbook, the art and science of organ donation and tissue preservation is examined. Through this authoritative text by leaders in the field, the editors provide a state of the art review of modern preservation techniques, patient selection and screening criteria, as well as best practices for multi-organ procurement. Information presented in the book will familiarize readers with the initial steps of determining organ availability which ultimately enables health care professionals to realize the extraordinary potential of successful multi-organ transplant procedures. This guide is intended to be a fundamental resource for students, residents, faculty and staff for all disciplines allied to health care delivery and organ donation.

Non-heart-beating donors (individuals whose deaths are determined by cessation of heart and respiratory function rather than loss of whole brain function) could potentially be of major importance in reducing the gap between the demand for and available supply of organs for transplantation. Prompted by questions concerning the medical management of such donors--specifically, whether interventions undertaken to enhance the supply and quality of potentially transplantable organs (i.e. the use of anticoagulants and vasodilators) were in the best interests of the donor patient--the U.S. Department of Health and Human Services asked the Institute of Medicine to examine from scientific and ethical points of view "alternative medical approaches that can be used to maximize the availability of organs from [a] donor [in an end-of-life situation] without violating prevailing ethical norms...." This book examines transplantation supply and demand, historical and modern conceptions of non-heart-beating donors, and organ procurement organizations and transplant program policies, and contains recommendations concerning the principles and ethical issues surrounding the topic.

Each day, nearly 60 Americans receive a transplanted kidney, liver, or other organâ€"a literal "second chance at life"â€"but 11 others die waiting for an organ transplant. The number of donors, although rising, is not growing fast enough to meet the increasing demand. Intended to improve the current system of organ procurement and allocation, the "Final Rule," a 1998 regulation issued by the U.S. Department of Health and Human Services, sparked further controversy with its attempts to eliminate the apparent geographic disparities in the time an individual must wait for an organ. This book assesses the potential impact of the Final Rule on organ transplantation. It also presents new, original analyses of data, and assesses medical practices, social and economic observations, and other information on: access to transplantation services for low-income populations and racial and ethnic minority groups; organ donation rates; waiting times for transplantation; patient survival rates and organ failure rates leading to retransplantation; and cost of organ transplantation services.

This book is a comprehensive and innovative guide to abdominal solid organ transplantation (SOT). It explains the main immunological problems involved in abdominal SOT, reviews indications for liver, kidney, and small bowel transplantation, and provides detailed descriptions of techniques for procurement and transplantation. In addition, technical, infectious, and immunological complications and their treatment are fully described. Special attention is devoted to the indications for and outcomes of combined kidney-liver and kidney-pancreas transplantation. Clear advice is provided on donor selection and donor safety, and the book concludes by examining medical disease and the risk of solid and hematologic malignancies after transplantation. Abdominal SOT has become the treatment of choice for various end-stage chronic diseases of the liver, kidney, and foregut. Improved knowledge of immunology, the introduction of new immunosuppressive agents, and advances in surgical techniques have all increased the number of potential candidates and led to better outcomes. It is therefore unsurprising that more and more surgeons, physicians, and scientists, as well as students and nurses, are becoming interested in abdominal SOT. This book will provide all practitioners with an excellent, up-to-date summary of knowledge in the field.