Proteomics In Domestic Animals From Farm To Systems Biology

Proteomics, like other post-genomics tools, has been growing at a rapid pace and has important applications in numerous fields of science. While its use in animal and veterinary sciences is still limited, there have been considerable advances in this field in recent years, in areas as diverse as physiology, nutrition and food of animal origin processing. This is mainly as a consequence of a wider availability and better understanding of proteomics methodologies by animal and veterinary researchers. This book provides a comprehensive, state-of-the-art account of the status of farm-animal proteomics research, focusing on the principles behind proteomics methodologies and its specific applications and offering clear example.

The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction research. This text will be written by leading international proteomics experts and essential for researchers in the fields of animal biology and veterinary medicine.

Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.

This book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle. These emerging technologies help to extensively enhance our understanding of the etiology and pathogenesis of periparturient diseases of transition dairy cows. The book includes a chapter dedicated to ‘omics’ sciences and one that discusses the myths established in animal and veterinary sciences in recent decades and emerging, new paradigms. The diseases discussed include metritis, mastitis, laminitis, ketosis, rumen acidosis, periparturient immunosuppression, gastrointestinal microbiota and their involvement in disease, infertility, fatty liver, milk fever, and retained placenta. This book is intended for academics, veterinarians, animal nutritionists, researchers, and graduate students working in the field of ‘omics sciences’ with a special interest in dairy cattle health.

Food Proteomics: Technological Advances, Current Applications and Future Perspectives addresses many of the food proteomic issues in the industry today. Food proteomics continues to be an emerging field, becoming increasingly important in product innovation, food safety, food quality and health. The book is divided into sections describing the role of proteomics in the field of food science, conceptual background methodological aspects, and bioinformatic tools employed in the field. The book describes proteomic studies collected from the most relevant animal and vegetables species in food production and discusses important food challenges from a proteomic point-of-view. This is an essential and practical reference that provides analytical tools to help introduce technical innovations in the food industry with the latest scientific information useful and accessible to new researchers in the field as well as advanced. Includes precise proteomic information on a specific category Provides proteomic studies of the most common vegetable and animal species Presents proteomic methodologies, including bioinformatics for effective analysis in food science Discusses food challenges such as allergens, authentication and food safety

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Proteomics is the large-scale study of the proteome, i.e. a set of proteins being expressed in a certain fluid, tissue, organ or organism. The value of this advanced technology is being recognised in farm animal and veterinary sciences from 'farm to fork'. The potential of proteomics is unequivocal in holding a significant promise in applications such as vaccine and drug development, physiology, toxicology, animal product quality and food safety. Proteomics has been growing steadily during the last 3-4 years and, as time goes by, proteomics-based studies are more and more common, not just to scientists but to the general public as well, unravelling the full potential of this innovative technology. This book reflects the will of a group of multi-disciplinary scientists that merge innovation with excellence of research and to whom the dissemination of knowledge and discovery through cooperation is a key point. It is of interest to scientists at the early stages of their careers as well as to researchers well established in the field and to whom proteomics may be the necessary next step towards more in-depth research activities. By providing a collection of diverse scientific interests, 'Farm Animal Proteomics 2014' demonstrates the vitality of the area and the importance it holds to animal and food research, to science, industry, government agencies, the consumer and ultimately the society as a whole.

"Proteomics is a field with growing interest in almost every area of life sciences. Proteomic techniques, along with potential and obtained results have long been key components of biomedical and pharmaceutical research. In agriculture, animal and veterinary research however, use of proteomics is still limited, despite the large number of potential applications. As a result, there is a pressing need for wider use and dissemination of proteomics in animal and veterinary science research. This book meets this need by bridging the gap between experts in the technology of proteomics and those at the forefront of research into many facets of animal physiology and pathophysiology. The book encompasses a wide range of topics: from muscle and meat proteomics to acute phase proteins and proteomics in aquaculture, to name but a few. The book summarily presents the state of the art in farm animal proteomics research in Europe, providing readers with interesting examples of the applications of this set of advanced technologies as well as useful contact details of colleagues with expertise in the field. The book will be of interest to scientists at the cutting edge of animal and veterinary research who are currently, or are considering, analytical investigation and identification of protein in animal tissue and in pathogens in health and disease. Furthermore the book will provide an insight for proteomic specialists in demonstrating the breadth of applications that their technology can have in animal and food research."