Pyrantel Parasiticide Therapy In Humans And Domestic Animals

Pyrantel Parasiticide Therapy in Humans and Domestic Animals presents a single source history and reference on the parasiticide activity and pharmacology of the tetrahydropyrimidines and their salts in humans and domestic animals, also collating evidence that resistance to pyrantel has developed in human and domestic animal nematodes. Other books of this nature have been compiled historically for specific anthelmintic compounds, but none has been written to date for the pyrantel family of drugs. Pyrantel, a nicotinic receptor agonist, has been used in domestic animal and human medicine since the 1970’s to control two important nematode groups, the hookworms and the roundworms. Given the zoonotic potential of these parasites, pyrantel has served a dual role in helping to protect the health of both domestic animals and the public for more than 45 years. Easy-to-use reference guide on the anthelmintic pyrantel for clinicians, parasitologists, and researchers in human and veterinary medicine Addresses current issues of resistance, along with combination uses against anthelmintic resistant parasites Presents useful, authoritative information (chemical, pharmaceutical, clinical, etc.) for the pyrantel family of compounds Includes a discussion on pyrantel’s potential role in combination therapies Provides cutting-edge material, and will be an evolving area of scientific discussion of treatment options in the future

Canine Parasites and Parasitic Diseases offers a concise summary, including the distribution, epidemiology, lifecycle, morphology, clinical manifestations, diagnosis, prophylaxis and therapeutic measures on the most important parasites affecting dogs. The book includes their classification, structure, lifecycles, occurrence, and the diagnosis and treatment of infestations. Chapters are presented in a consistent and logical format with extensive use of tables, photographs and line drawings that help veterinarians and students quickly find answers to questions. The book informs on 100 different species of parasite related to the canine world and is is aimed not only at veterinary practitioners but also in dog enthusiasts, pharmacies and laboratories. Fully illustrated with high-quality figures and illustrations Provides insights on the risk factors and prevention of parasite infections in dogs and gives guidelines for anthelmintic treatment Serves professionals, students, parasitologists and veterinary scientists Present an easy-to-use handbook on the identification of canine parasites and the diseases associated with parasitic infection

Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods, Volume Two presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds. Addresses current issues of resistance, along with combination uses for resistant parasites Presents useful, authoritative information (chemical, pharmaceutical, clinical, etc.) for the pyrantel family of compounds Includes a discussion on screening methods in combination therapies Provides cutting-edge material for an evolving area of scientific discussion Includes in vitro and in vivo screens and parasite maintenance and culture methods

Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods, two-volume set, presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds. Addresses current issues of resistance, along with combination uses for resistant parasites Presents useful, authoritative information (chemical, pharmaceutical, clinical, etc.) for the pyrantel family of compounds Includes a discussion on screening methods in combination therapies Provides cutting-edge material for an evolving area of scientific discussion Includes in vitro and in vivo screens and parasite maintenance and culture methods

Publishers Weekly Most Anticipated Books of Fall 2019 A New York Times Editor’s Pick People Best Books Fall 2019 Chicago Tribune 28 Books You Need to Read Now Booklist’s Top Ten Sci-Tech Books of 2019 “It blew my mind to discover that teenage animals and teenage humans are so similar. Both are naive risk-takers. I loved this book!” —Temple Grandin, author of Animals Make Us Human and Animals in Translation A revelatory investigation of human and animal adolescence and young adulthood from the New York Times bestselling authors of Zoobiquity. With Wildhood, Harvard evolutionary biologist Barbara Natterson-Horowitz and award-winning science writer Kathryn Bowers have created an entirely new way of thinking about the crucial, vulnerable, and exhilarating phase of life between childhood and adulthood across the animal kingdom. In their critically acclaimed bestseller, Zoobiquity, the authors revealed the essential connection between human and animal health. In Wildhood, they turn the same eye-opening, species-spanning lens to adolescent young adult life. Traveling around the world and drawing from their latest research, they find that the same four universal challenges are faced by every adolescent human and animal on earth: how to be safe, how to navigate hierarchy; how to court potential mates; and how to feed oneself. Safety. Status. Sex. Self-reliance. How human and animal adolescents and young adults confront the challenges of wildhood shapes their adult destinies. Natterson-Horowitz and Bowers illuminate these core challenges through the lives of four animals in the wild: Ursula, a young king penguin; Shrink, a charismatic hyena; Salt, a matriarchal humpback whale; and Slavc, a roaming European wolf. Through their riveting stories—and those of countless others, from adventurous eagles and rambunctious high schooler to inexperienced orcas and naive young soldiers—readers get a vivid and game-changing portrait of adolescent young adults as a horizontal tribe, sharing behaviors and challenges, setbacks and triumphs. Upending our understanding of everything from risk-taking and anxiety to the origins of privilege and the nature of sexual coercion and consent, Wildhood is a profound and necessary guide to the perilous, thrilling, and universal journey to adulthood on planet earth.

Parasitology: An Integrated Approach, provides a concise, student-friendly account of parasites and parasite relationships that is supported by case studies and suggestions for student projects. The book focuses strongly on parasite interactions with other pathogens and in particular parasite-HIV interactions, as well as looking at how host behaviour contributes to the spread of infections. There is a consideration of the positive aspects of parasite infections, how humans have used parasites for their own advantage and also how parasite infections affect the welfare of captive and domestic animals. The emphasis of Parasitology is on recent research throughout and each chapter ends with a brief discussion of future developments. This text is not simply an updated version of typical parastitology books but takes an integrated approach and explains how the study of parasites requires an understanding of a wide range of other topics from molecular biology and immunology to the interactions of parasites with both their hosts and other pathogens.

This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.

Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer and pet owner. These advantages have resulted in them growing in popularity in recent years. The pharmaceutical scientist is faced with many challenges when innovating new products in this demanding field of controlled release. This book provides the reader with a comprehensive guide on the theories, applications, and challenges associated with the design and development of long acting veterinary formulations. The authoritative chapters of the book are written by some of the leading experts in the field. The book covers a wide scope of areas including the market influences, preformulation, biopharmaceutics, in vitro drug release testing and specification setting to name but a few. It also provides a detailed overview of the major technological advances made in this area. As a result this book covers everything a formulation scientist in industry or academia, or a student needs to know about this unique drug delivery field to advance health, production and reproduction treatment options and benefits for animals worldwide.