Radiotherapy Of Intraocular And Orbital Tumors

Radiotherapy of Intraocular and Orbital Tumors presents a new approach to the role of radiation therapy in the management of ophthalmic cancer. The indications for ultrasonography, computed tomography, and magnetic resonance imaging studies are analyzed, and treatment techniques, together with their results, are described for each tumor. Particle beam and plaque irradiation are reviewed, and conservative and surgical management of radiation effects are detailed. In the past, most books on this subject included a chapter on radiotherapy but emphasized the dangers of radiation complications. However, great progress in understanding the effects of irradiation upon the tissues of the eye and orbit, new therapeutic equipment, and new imaging techniques (CT, MRI) allow for careful treatment planning. This book has taken the long overdue step of reconsidering the role of irradiation of the eye so that it may take its place as a respected, rather than feared, treatment in the combined modality approach so important today. Together with experts in relevant fields, the editors have produced a refreshingly clear and thoroughly referenced volume which will be a valuable asset to all ophthalmologists, radiation oncologists, pediatricians, endocrinologists, oncologists, and residents in training, as well as to students in these disciplines.

Radiotherapy of Intraocular and Orbital Tumors presents a new approach to the role of radiation therapy in the management of ophthalmic cancer. The indications for ultrasonography, computed tomography, and magnetic resonance imaging studies are analyzed, and treatment techniques, together with their results, are described for each tumor. Particle beam and plaque irradiation are reviewed, and conservative and surgical management of radiation effects are detailed. In the past, most books on this subject included a chapter on radiotherapy but emphasized the dangers of radiation complications. However, great progress in understanding the effects of irradiation upon the tissues of the eye and orbit, new therapeutic equipment, and new imaging techniques (CT, MRI) allow for careful treatment planning. This book has taken the long overdue step of reconsidering the role of irradiation of the eye so that it may take its place as a respected, rather than feared, treatment in the combined modality approach so important today. Together with experts in relevant fields, the editors have produced a refreshingly clear and thoroughly referenced volume which will be a valuable asset to all ophthalmologists, radiation oncologists, pediatricians, endocrinologists, oncologists, and residents in training, as well as to students in these disciplines.

Provides up-to-date information on the diagnosis and treatment of cancers of the eye and orbit. The most recent data with respect to retinoblastoma, rhabdomyosarcoma, and melanoma are included. The presenting signs and symptoms of tumors are outlined, and indications for the various imaging modalities are analyzed. Treatment techniques, together with their results in respect of survival and local tumor control, are described in detail; throughout, special attention is paid to multimodality therapy. Potential complications of radiotherapy are described, and relevant information is provided on the management of radiation effects. The emphasis is on the need for a holistic approach to the patient that recognizes the wider role of irradiation of the eye now that more careful treatment planning is possible.

This publication, a conjoint effort by ocular oncologists and radiation oncologists, comprises ten chapters covering basic and advanced radiation therapy techniques followed by specific indications by location (uveal, retinal, orbital tumors, eyelid and conjunctival tumors) and complications of radiation therapy. A chapter on investigational use of radiation therapy for age-related macular degeneration is also included.

This book discusses current controversial topics and therapeutic strategies in the treatment of malignant and benign ocular diseases, with special emphasis on ocular tumors. Written by leading specialists, the articles highlight the latest developments in the diagnosis and therapy of retinoblastomas, uveal melanomas and malignant lymphomas. Further contributions include such topics as the optimization of dosimetry and design of radioactive eye plaques, the effects and side-effects of radiotherapy of age-related macular degeneration, and new approaches for perioperative organ-preserving brachytherapy for orbital tumors. Readers will be particularly interested in the discussion of possible side-effects of photon and proton beam radiotherapy of the eye and their minimization. Extensive data from clinical studies evaluating radiotherapy in the management of endocrine orbitopathy are also provided. The final part is dedicated to radiotherapy of benign ocular diseases such as pterygium or choroidal and retinal hemangiomas. Compiling the most up-to-date and comprehensive information on ocular radiotherapy currently available and offering an interdisciplinary perspective, this book will be appreciated by ophthalmologists, radiotherapists and oncologists.

Orbital Tumors, 2nd edition discusses advances in orbital disease and their treatment, offering readers an up-to-date, single volume reference for orbital tumors. Divided into two parts, this book covers everything from advances in oncogenesis and its relationship to orbital tumors, to medical genetics and the role of imaging in diagnosis of orbital tumors. Additionally, new information on incidence and behavior of tumors resulting from environmental and social trends is included. Written and edited by leaders in the fields of ophthalmology and oncology, Orbital Tumors, 2nd edition builds upon the first edition, proving to be a useful reference for orbital specialists and of significant interest for everyone dealing with orbital pathology from a clinical and scientific point of view.

Since the publication of the first edition of Radiotherapy of Intraocular and Orbital Tumors in 1993 the treatment programs for cure have changed from the dominance of surgical resection to the utilization of radiation therapy with preservation of the eye intact and preservation of vision. In 2002 about 2,300 primary eye tumors will be diagnosed in the United states, 75% of which will be choroidal melanomas, 20% retinoblastomas, and the remainder a wide variety of tumors - malignant lymphoma, rhabdomyosarcomas, liposarcomas, meningiomas, malignant fibrous histiocytomas, etc. Even so, the majority of malignant tumors of the eye are metastatic, primarily from cancers of the lung or breast. The impact of newer imaging studies, including computed tomography, magnetic resonance imaging, and ultrasound with and without contrast medium, have allowed for better tumor definition, more precise treatment techniques, and major improvement in local control, with preservation of the eye intact and excellent survival. The better histologic definition of the tumor has selected more appropriately the cases suitable for adjuvant chemotherapy particularly demonstrated by the combined integrated multimodal treatment of rhabdomyosarcoma without enucleation. Surgical techniques are now being reserved for biopsy and for treatment failures, a dramatic change in treatment approaches since 1993. The second edition by Sagerman and Alberti clearly demonstrates this major change in treatment. The volume explores the impact of diagnostic workup, the role of surgery, the role of external beam radiation therapy, the use of radioactive plaques, photocoagulation, cryotherapy, and other less major surgical procedures.

This represents the most up-to-date text on the diagnosis and surgical treatment of orbital tumors. The heavily illustrated format uses a step-by-step approach guide which will make this the most practical and attractive reference ever published on this topic.