Recent Advances In The Treatment Of Colorectal Cancer

This book examines the latest indications and techniques for various endoscopic and surgical colorectal cancer treatments, discussing not only on the standard lymph node dissection technique, but also on laparoscopic and robotic surgery. It particularly focuses on the treatment of rectal cancer, with chapters on radiation therapy and sphincter preservation, which is analyzed from Asian perspectives that differ from those of Western treatment. Further, it presents the results of combining chemotherapy and oral drugs, as well as the treatment of hereditary cancer using next-generation sequencing for genetic diagnosis. Edited by surgeons who have pioneered the research and treatment of colorectal cancer, Recent Advances in the Treatment of Colorectal Cancer presents extensive information for clinicians such as endoscopic surgeons, colorectal surgeons, as well as oncologists and researchers specializing in this field. Providing a foundation for new ideas, it enables advanced surgeons to further develop their skills and offers thought-provoking, instructive and informative reading for residents, students and medical staff.

Colorectal cancer is one of the commonest cancers affecting individuals across the world. An improvement in survival has been attributed to multidisciplinary management, better diagnostics, improved surgical options for the primary and metastatic disease and advances in adjuvant therapy. In this book, international experts share their experience and knowledge on these different aspects in the management of colorectal cancer. An in depth analysis of screening for colorectal cancer, detailed evaluation of diagnostic modalities in staging colorectal cancer, recent advances in adjuvant therapy and principles and trends in the surgical management of colorectal cancer is provided. This will certainly prove to be an interesting and informative read for any clinician involved in the management of patients with colorectal cancer.

Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.

The latest guidance on challenging and controversial aspects of colorectal cancer Colorectal cancer is one of the most common forms of cancer in the US and Europe. Thousands of people are diagnosed with the disease every year and nearly half of these die as a result. As colorectal cancer is curable when detected early, a significant proportion of these deaths could be prevented by earlier diagnosis. Much has changed since the publication of the first edition of this book in 2001: introduction of screening programs, improved diagnosis and surgery for rectal cancer, and advances in adjuvant and palliative medical therapy to name but a few. Challenges in Colorectal Cancer provides the most up-to-date information on the new and emerging treatments. The second edition looks at the total patient management of this condition and is aimed at the entire medical team caring for those with colorectal cancer. It also contains the latest guidelines on epidemiology and prevention of colorectal cancer, and the application of molecular genetics. The expanded international editor team present advice on surgical management, including new laparoscopic and endoscopic techniques and the role of the pathologist. They also review hot topics in colorectal cancer treatment, including the role of radiotherapy, options for chemotherapy and new developments in vaccines and immunotherapy.

With international experts sharing their experience and knowledge on these different aspects in the management of colorectal cancer, this book has this opportunity to offer all physicians treating colorectal cancer, as well as researchers, updated information concerning the biology, diagnosis, screening, and treatment of colorectal carcinoma. This book provides a detailed evaluation of diagnostic modalities, in-depth analysis of screening for colorectal cancer, recent advances in treatment, and principles and trends in the management of colorectal cancer. This updated knowledge will be an interesting and informative read for any clinician involved in the management of patients with colorectal cancer. In addition, readers such as related physicians, researchers, and colorectal cancer patients are potential beneficiaries of this book.

Colorectal Cancer is a complex disease caused by the interaction of hereditary and environmental factors that can be classified based on their importance. Colorectal Cancer Diagnosis and Therapeutic Updates provides comprehensive information about the diagnosis and treatment of colorectal cancer. Chapters first cover the fundamentals of colorectal cancer diagnosis, progressing further towards explaining therapeutic modalities and recent advances in the understanding of the disease. Key Features - 11 organized, reader-friendly chapters that provide a complete overview of colorectal cancer - Covers the colorectal cancer diagnosis, screening and histopathology - Covers multimodal treatment of colorectal cancer, including chemotherapy, radiotherapy and robotic surgery - Covers the management and surveillance of colorectal cancer - Explains the key biochemical mechanisms involved in colorectal cancer treatment - Covers recent information about colorectal cancer theranostics and drug delivery - Includes references for further reading in every chapter The book serves as an introductory reference for medical students and residents on the subject of colorectal cancer. It also serves as a quick reference on the disease for the practicing general physician.