Renal Physiology And Hydrosaline Metabolism

This volume discusses renal function and the mechanisms by which the kidney regulates the composition and volume of the extracellular fluid. It also highlights the role of the kidney in the development and progression of arterial hypertension. Most textbooks of renal physiology are based in mammalians physiology and mostly human physiology of the kidney, but the authors considered that this book should also include other species to include the broad spectrum of students and researchers in the life and biomedical sciences. In this sense, we included chapters such as comparative osmoregulation in non-mammalian vertebrates and we emphasize that in vertebrates like fish, reptiles, amphibians and birds, the kidneys and extrarenal organs are vital to maintain fluid homeostasis. The purpose of the book is to provide a concise frame of knowledge in a clear and direct language, of the renal function to medical and biological sciences students. In the context of normal renal function, we provide pathophysiological basis for chronic renal diseases and hypertension with the participation of renal vasoactive hormones. This book is used as textbook in several physiology courses for medical, nursing and biological sciences students at the Pontifical Catholic University of Chile, Finis Terrae University, Universidad San Sebastian as well as other universities.

Each chapter in this authoritative volume is written by a well-known physiologist who has contributed to our current understanding of renal function. Together the authors offer a unique, inside perspective on the historical record of the discipline, from its roots in the ancient world to the most recent findings of modern times. Among the many topics discussed are renal blood flow and the dynamics of glomerular filtration; the clearance concept in renal physiology; micropuncture and microperfusion; transport of electrolytes across renal tubules; and diuretics and renal drug development.

This revised edition of a monograph which introduces the student to the basic science principles and clinical applications of renal physiology begins with structure and function of the kidneys and a step-by-step review of renal processes. The text emphasizes the core body of information needed to fully understand renal haemodynamics, sodium and water excretion, renal regulation of potassium, hydrogen ion and calcium/phosphate balance.

The complexity and copious number of details that must be mastered in order to fully understand renal physiology makes this one of the most daunting and intimidating topics covered in the first year of medical school. Although this is often only a 2-4 week module during the general physiology course, it is essential that students understand the foundations of renal physiology, and general physiology texts are often not detailed enough to provide students with what they need to master this difficult subject. This first edition, and third volume in the Integrated Physiology Series, offers students a clear, clinically oriented overview of renal physiology. The lecture-style format, conversational tone, and final Integration chapter offset the difficult and intimidating nature of the subject. Chapter outlines, learning objectives, and end-of-chapter summaries highlight key concepts for easier assimilation. Other pedagogical features include clinical cases, Thought Questions, Putting It Together sections, Editor's Integration boxes, review Q&A, and online animations -- all designed specifically to reinforce clinical relevance and to challenge the student in real-world problem-solving.

The first edition of this book was well received by updated. The two of us have made further collab orative efforts to present a better understanding of medical students, graduate students, and clinicians interested in furthering their understanding of basic the function of the kidney in conjunction with the principles of renal physiology. Most of the reviews most recent anatomical findings. of the first edition and comments from the various The second edition consists of 13 Chapters and 3 instructors who used the book were very positive Appendices. As in the first edition, the anatomical and complimentary with regard to the presentation description of the kidney is incorporated into the of the physiological information and the use of the various chapters dealing with kidney functions. Most system analysis approach to describe renal function. of the anatomical information was written by Wil These positive and encouraging comments over the helm Kriz. The physiological information was writ past nine years, since the publication of the first ten by Esmail Koushanpour, except for Chapter 12 edition, gave us the impetus to consider the prepa which was jointly written. Chapters 1 through 3 were ration of a second edition.

A classic nephrology reference for over 25years, Seldin and Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin and Giebisch’s The Kidney is your number one source for information. Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions

Knowledge of renal physiology and pathophysiology has expanded enormously in the past decade. Kidney Physiology provides a clear understanding of normal kidney function, with a focus on information that is immediately applicable to clinical practice.