Rudolf Magnus

Most medical doctors have probably during their studies heard of the `Magnus and De Kleijn reflexes' and may have been aware of their relation to posture. But they know little about their significance and nothing about the man who unravelled the complex physiology of these reflexes and about his work. Rudolf Magnus lived from 1873 until 1927. His work on the physiology of posture was initiated during a short period of work with Sherrington in Liverpool in 1908. Though Magnus was also an authority in the field of pharmacology, it was particularly his neurophysical work on posture which made him known worldwide. It led to his nomination, together with De Kleijn, for the Nobel Prize in 1927. Unfortunately he died before the decision was made. In this illustrated biography Magnus' family background and his student years are described in a lively way. Fragments of the diary of his journey to England in 1898 and the description of his scientific career in Heidelberg will enlighten those interested in the history of how science was conducted during his lifetime. His lectures on Goethe as a scientist are also included. This is followed by Magnus' life as Professor of Pharmacology in Utrecht, and his studies on animal postures and experimental pharmacology. Finally Magnus' legacy is described.

Pituitary, Adrenal and the Brain

The life and work of a scientist who spent his career crossing disciplinary boundaries—from experimental neurology to psychiatry to cybernetics to engineering. Warren S. McCulloch (1898–1969) adopted many identities in his scientific life—among them philosopher, poet, neurologist, neurophysiologist, neuropsychiatrist, collaborator, theorist, cybernetician, mentor, engineer. He was, writes Tara Abraham in this account of McCulloch's life and work, “an intellectual showman,” and performed this part throughout his career. While McCulloch claimed a common thread in his work was the problem of mind and its relationship to the brain, there was much more to him than that. In Rebel Genius, Abraham uses McCulloch's life as a window on a past scientific age, showing the complex transformations that took place in American brain and mind science in the twentieth century—particularly those surrounding the cybernetics movement. Abraham describes McCulloch's early work in neuropsychiatry, and his emerging identity as a neurophysiologist. She explores his transformative years at the Illinois Neuropsychiatric Institute and his work with Walter Pitts—often seen as the first iteration of “artificial intelligence” but here described as stemming from the new tradition of mathematical treatments of biological problems. Abraham argues that McCulloch's dual identities as neuropsychiatrist and cybernetician are inseparable. He used the authority he gained in traditional disciplinary roles as a basis for posing big questions about the brain and mind as a cybernetician. When McCulloch moved to the Research Laboratory of Electronics at MIT, new practices for studying the brain, grounded in mathematics, philosophy, and theoretical modeling, expanded the relevance and ramifications of his work. McCulloch's transdisciplinary legacies anticipated today's multidisciplinary field of cognitive science.

Topics in Neuroendocrinology

Neuropeptides and Brain Function

First multi-year cumulation covers six years: 1965-70.

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