Sex Steroids Effects On Brain Heart And Vessels

This book analyzes the effects of estrogens and progesterone on brain cells, the immune system, neuro inflammation, myelin formation and steroid receptor distribution, as well as their clinical impacts. It also explores the relationship between sex-steroid withdrawal and the development of brain symptoms such as hot flushes, sleep disorders, mood changes, depression and also cognitive disorders and dementia, as well as the effects of hormone menopause therapy on such symptoms and diseases. Starting with obstetrical history and cardiovascular risk in later life, the second part of the book examines the effects of estrogens and progestogens on vascular tissues, atherosclerosis and coronary heart diseases, as well as the impact of hormone replacement therapies on cardiovascular risks and mortality. This volume is a useful, clear and up-to-date tool for gynecologists, endocrinologists, neurologists and cardiologists, and serves as a valuable source of information for all physicians involved in women’s health.

Neurobiological Effects of Sex Steroid Hormones describes the neurobiological basis for the understanding of how sex steroid hormones, oestrogen and testosterone, interact with parts of the brain. The contributors have all made significant advances in the understanding of how these steroids regulate neural function, and how this activity is translated into reproductive behaviours necessary for the propagation of the species. This book covers a broad range of topics, extending from the molecular and cellular processes, through the action of steroids on neurotransmission, all the way to defining the brain circuitry involved in both male and female behaviour. This volume presents a snapshot of the rapidly advancing field of reproductive neuroendocrinology by the investigators who are most intimately involved with the discoveries.

This volume comprehensively focuses on polycystic ovary, metabolic syndrome and obesity and their impact on women’s health, reproduction and quality of life from adolescence to old age. PCOS is analyzed form the early origins - highlighting the importance of diagnosis, management and treatment starting from the high-risk period of adolescence - throughout infertility PCOS-related issues, pregnancy and menopause transition. All aspects of this syndrome are covered also in relation with endocrine and metabolic features that affects women’s health. This book is a very useful tool for gynecologists, endocrinologists, obstetricians, reproductive medicine and general practitioners and is an important resource for all physicians involved in women’s health.

Exploring Health Psychology provides comprehensive yet student-friendly coverage of both traditional topics in the field and important contemporary issues relating to reproductive, sexual, and psychological health. Using an informal, sometimes humorous narrative, the authors engage students of all interest levels, abilities, and learning styles by emphasizing the application of health and wellbeing psychology in their daily lives. Balancing depth and accessibly, each chapter describes the body systems relevant to a particular topic, incorporates up-to-date information and research, and contains relatable examples, real-world applications, compelling discussion and review questions, personal stories and vignettes, a running glossary, and more. Broad in scope, Exploring Health Psychology examines the interactions between biological, psychological, and sociocultural factors in psychological disorders and discusses their psychological and medical treatment. Critical psychological health issues such as anxiety and depression, the health of sexual and gender minorities, and the psychological dangers and pitfalls of the digital age are addressed to meet the needs of today’s students. An array of active learning features based on the SQ4R pedagogy—Survey, Question, Read, Recite, Reflect, and Review—enables students to take an active role in the learning process, develop effective study habits, strengthen critical and scientific thinking, and comprehend, retain, and apply the material.

The story of doctor Ferdinand Peeters (1918-1998) and his role in the development of the pill has held Belgium in thrall for almost a decade. It is time to introduce the real father of the contraceptive pill to the rest of the world. After years of research, Belgian journalist Karl van den Broeck concluded that not the American Gregory Pincus was the inventor of the pill. His prototype had so many adverse effects that it wasn’t a viable option in the long term. It was the Belgian doctor Ferdinand Peeters who, in 1959-1960, created the first clinically applicable contraceptive pill: Anovlar. It was this pill that set the standard for all future pills to follow. Ferdinand – Nand – Peeters was a devout Catholic and during an audience with pope John XXIII, he urged that the church should sanction the use of the Pill. But when Paul VI decided in 1968 that birth control other than the practice of periodic abstinence would remain forbidden, doctor Peeters didn’t breathe a word about his role in the development of the pill. Even his family was barely aware of it. In The Real Father of the Pill, Karl van den Broeck tells the long hidden story behind this invention, a story of innovation and threats, of grateful women and papal ambivalence. With this book doctor Peeters is finally given the recognition he deserves. This book includes the documentary The Real Father of the Pill. More information can be found in the book.

The book systematically describes the clinical and scientific aspects of cardiovascular calcification. Chapters detail the mechanisms associated with arterial and valve calcification, relevant risk factors, pathophysiology and the latest therapeutic techniques. Recent diagnostic technological developments including how computed tomography (CT) scanning can be utilized along with Agatston score to quantify coronary arterial calcification when investigating whether a patient for sub-clinical atherosclerosis are covered. The correlation with the presence of arterial calcification and extent of coronary stenosis is also explored. Cardiovasular Calcification details relevant aspects of the basic science and reviews the latest pathological and therapeutic techniques used in treating patients with cardiovascular calcification. It is therefore an essential resource for practicing cardiologists, cardiac surgeons, vascular specialists and radiologists.

This book comprehensively addresses female and male fertility preservation. It discusses in detail all major aspects of fertility preservation in both sexes, explains the basis of fertility preservation, and highlights the currently available techniques; further chapters are dedicated to specific diseases. The book offers an essential reference guide for all physicians, specialists or not, seeking to improve their grasp of female and male fertility preservation.

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.