Silencing Heterochromatin And Dna Double Strand Break Repair
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Silencing Heterochromatin and DNA Double Strand Break Repair
Author | : Kevin D. Mills |
Publsiher | : Springer Science & Business Media |
Total Pages | : 129 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9781461543619 |
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The field of DNA repair is vast and advancing rapidly. Recent investigations have begun to focus on the involvement of chromatin in the repair of broken DNA. Although I have no doubt that many breakthroughs in our understanding of chromatin, chromatin regulation, and DNA repair lie in our future, presently this is a new line in inquiry. As such there are many, many unanswered questions. Indeed, most of the correct questions have probably not even been asked yet. Here I have attempted to present a review of some of the current body of knowledge that may prove relevant to understanding the role of chromatin in DNA repair. Because the volume of research, and the relevant findings, come from a staggering array of labs, systems, and ideas I have focused primarily on findings developed from the study of the budding yeast Saccharomyces cerevisiae. Unfortunately, this means that I have left out a great deal of information. It is my hope, however, that the information I do detail, particularly in Chapter 1, will give a flavor for the scope of the problem and perhaps highlight some of the interesting directions this field is taking, or may one day take. I would also point out that the primary research that is presented herein is not in any way meant to represent the comprehensive scope of research being performed. To understand DNA repair will require investigation from innumerable labs, performed by innumerable researchers, moving in unexpected directions.
Protecting the Code DNA Double Strand Break Repair Pathway Choice
Author | : David Maranon,Judit Jimenez Sainz,Sylvie M. Noordermeer,Matthias Altmeyer,Jenny Kaur Singh |
Publsiher | : Frontiers Media SA |
Total Pages | : 258 |
Release | : 2023-03-31 |
Genre | : Science |
ISBN | : 9782832500477 |
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Gene Regulation Epigenetics and Hormone Signaling
Author | : Subhrangsu S. Mandal |
Publsiher | : John Wiley & Sons |
Total Pages | : 656 |
Release | : 2017-05-09 |
Genre | : Science |
ISBN | : 9783527697243 |
Download Gene Regulation Epigenetics and Hormone Signaling Book in PDF, Epub and Kindle
The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, major emphasis is placed on pathological conditions, aiming at the many physiologists and developmental biologists who are familiar with the importance and mechanisms of hormone regulation but have a limited background in epigenetics.
Regulation of DNA Double Strand Break Repair by Local Chromatin Architecture
Author | : Sérgio Fernandes de Almeida,Pablo Huertas,Gaelle Legube |
Publsiher | : Frontiers Media SA |
Total Pages | : 117 |
Release | : 2020-09-02 |
Genre | : Science |
ISBN | : 9782889639687 |
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Protein Phosphorylation in Human Health
Author | : Cai Huang |
Publsiher | : IntechOpen |
Total Pages | : 0 |
Release | : 2012-09-06 |
Genre | : Medical |
ISBN | : 9535107372 |
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15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.
Advances in Chromatin Research and Application 2012 Edition
Author | : Anonim |
Publsiher | : ScholarlyEditions |
Total Pages | : 397 |
Release | : 2012-12-26 |
Genre | : Science |
ISBN | : 9781464993800 |
Download Advances in Chromatin Research and Application 2012 Edition Book in PDF, Epub and Kindle
Advances in Chromatin Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chromatin. The editors have built Advances in Chromatin Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chromatin in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Chromatin Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Histone Deacetylases
Author | : Eric Verdin |
Publsiher | : Springer Science & Business Media |
Total Pages | : 352 |
Release | : 2007-11-06 |
Genre | : Medical |
ISBN | : 9781597450249 |
Download Histone Deacetylases Book in PDF, Epub and Kindle
A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.
Plant Gene Silencing
Author | : M.A. Matzke,A.J.M. Matzke |
Publsiher | : Springer Science & Business Media |
Total Pages | : 297 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9789401141833 |
Download Plant Gene Silencing Book in PDF, Epub and Kindle
This book is an up-to-date and comprehensive collection of reviews on various aspects of epigenetic gene silencing in plants. Research on this topic has undergone explosive growth during the past decade and has revealed novel features of gene regulation and plant defense responses that also apply to animals and fungi. Gene silencing is relevant for agricultural biotechnology because stable expression of transgenes is required for the successful commercialization of genetically engineered crops. The reviews have been written by distinguished authors who have made significant contributions to plant gene silencing research. This volume supersedes other books on gene silencing by focussing on plant systems, where many pioneering experiments have been performed, and by including the latest developments from top laboratories. The book is geared toward advanced students of genetics and plant sciences as well as applied and basic research scientists who work with transgenic organisms and epigenetic regulation of gene expression.