Stem Cell Repair And Regeneration

Stem cell research is one of the leading "cutting edge" areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by the field's leading scientists and covers many of the areas in which stem cells are becoming increasingly important, such as in organ repair and regeneration. Stem cells offer the possibility of cell therapy issues to treat a myriad of diseases, conditions, and disabilities including Parkinson's and Alzheimer's diseases, spinal cord injury, stroke, heart disease, and diabetes.

Stem cell research is one of the leading “cutting edge” areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by the field's leading scientists and covers many of the areas in which stem cells are becoming increasingly important, such as in organ repair and regeneration. Stem cells offer the possibility of cell therapy issues to treat a myriad of diseases, conditions, and disabilities including Parkinson's and Alzheimer's diseases, spinal cord injury, stroke, heart disease, and diabetes. Contents:An Introduction to Stem and Progenitor Cell Biology (M R Alison)Asymmetric Self-Renewal: The Mark of the Adult Stem Cell (J L Sherley)Transcriptional Regulation of Blood Stem Cells (B Göttgens)Post-natal Neovascularization — The Role of Endothelil Progenitor Cells, Growth Factors and the Extracellular Matrix (S Rahman et al.)Creating Designer Cells: Genetic Engineering of Stem Cells by Site-Specific Recombination (F Edenhofer & M Peitz)Kinetic Considerations for Stem Cell Therapy (M Gordon)Stem Cells and Tissue Engineering (A Vats et al.)Human Foetal Mesenchymal Stem Cells (J Chan et al.)Gene-Modified Mesenchymal Stem Cells as Cytoreagents for Regenerative Therapy (H Hamada)Pharmacological Characterisation of Embryonic Stem Cell-Derived Cardiomyoctye Cultures (N N Ali et al.)Adult Stem Cells in Cardiac Cellular Transplantation (I Dimarakis)Pancreas and Liver Regeneration and Neogenesis (R R Dodge)Extrahepatic Stem Cells in Liver Regeneration and Repair (A D Sharma & M Ott)Overview of Progress in the Differentiation of Embryonic Stem Cells into Pancreatic Beta-Cell Derivatives (J Jones et al.)Stem Cells and Clinical Application (N Levičar)Application of MRI to Stem Cell Imaging (K Bhakoo et al.) Readership: Life scientists, medical doctors and surgeons in academia and industry interested in stem cells and developing stem cell therapies. Scientists in biotechnology and pharmaceutical industries. Key Features:Comprehensive collection of many significant topics; from stem cell basics to stem cell therapyDefinitive and up-to-date guide to where and how stem cells can be used in repair and regenerationKeywords:Stem Cells;Cell Therapy;Tissue Engineering;Organ Regeneration;Liver;Pancreas;Heart

A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.

Annotation This second book in the Stem Cell Repair and Regeneration series provides a deeper exploration of the therapeutic potential of undifferentiated human stem cells. Regenerative medicine is an extremely fast-moving field which is evolving from the initial days of hype and excitement to a more realistic appraisal of the role of stem cells in the treatment of degenerative disorders. The series aims to keep abreast of these changes by combining new knowledge in stem cell biology and therapeutic applications. The current volume contains papers by the field's leading scientists and explores the current knowledge on cell therapy for different diseases and injured organs, including diabetes, liver and heart disease.

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Regenerative Medicine is a fastly emerging interdisciplinary field of research and clinical therapies on the repair, replacement or regeneration of cells, tissues or organs in congenital or acquired disease. This new field of research and clinical development focussing on stem cell science and regenerative biology is just starting to be the most fascinating and controversial medical development at the dawn of the 21st century. Viewing the great expectations to restructure and regenerate tissue, organs or organisms the current attempts of scientist and physicians are still in an early phase of development. This new textbook on “Regenerative Medicine – from protocol to patient” is aiming to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. The international leading experts from four continents describe the latest scientific and clinical knowledge of the field of “Regenerative Medicine”. The process of translating science of laboratory protocols into therapies is explained in sections on basic science, clinical translation, regulatory, ethical and industrial issues. The textbook is aiming to give the student, the researcher, the health care professional, the physician, and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practised therapies in Regenerative Medicine.

The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, the exploitation of the planet's natural resources has also resulted in some undesirable consequences such as diminished species biodiversity, climate change, environmental contamination, and intellectual property right and patent concerns.This book discusses the role of biological, ecological, environmental, ethical, and economic issues in the interaction between biotechnology and biodiversity, using different contexts. No other book has discussed all of these issues in a comprehensive manner. Of special interest is their impact when biotechnology is shared between developed and developing countries, and the lack of recognition of the rights of indigenous populations and traditional farmers in developing countries by large multinational corporations.