Steroid Biochemistry

Advances in Steroid Biochemistry and Pharmacology, Volume 4 provides information pertinent to the fundamental aspects of steroid biochemistry and pharmacology. This book covers a variety of topics, including cellular biochemistry, pituitary hormones, corticosteroids, and steroid hormones. Organized into seven chapters, this volume begins with an overview of the potential effects of steroids on cellular biochemistry. This text then examines the development of sleep-monitoring methods, together with methods of plasma sampling that enable very frequent specimen to be taken without disturbing the subject. Other chapters consider the usefulness of sleep-related growth hormone release in diagnosis in both children and adult. This book discusses as well the versatile effect of corticosteroids on the cellular components of the connective tissue. The final chapter deals with the functioning of the adrenal cortex and its control by adrenocorticotropic hormone (ACTH). This book is a valuable resource for biochemists, histochemists, biologists, pharmacologists, clinicians, and experimental endocrinologists.

An attempt has been made to attract contributions which illustrate the importance of certain enzymatic processes involved in steroid biosynthesis and metabolism and, in some cases, leading to steroidal action in target sites. Investigators actively engaged in research in such areas were invited to present their material in a manner which they considered fitting. It is hoped that as a result if this, the publication will possess sufficient depth to warrant approval. The blend of review material and experimental data originating in the author laboratories will, it is felt, make for useful reading.

An attempt has been made to attract contributions which illustrate the importance of certain enzymatic processes involved in steroid biosynthesis and metabolism and, in some cases, leading to steroidal action in target sites. Investigators actively engaged in research in such areas were invited to present their material in a manner which they considered fitting. It is hoped that as a result if this, the publication will possess sufficient depth to warrant approval. The blend of review material and experimental data originating in the author laboratories will, it is felt, make for useful reading.

Recent Advances in Steroid Biochemistry contains the proceedings of the Second International Symposium of the Journal of Steroid Biochemistry. Separating 38 papers as chapters, this book discusses the partial purification of steroid-receptor complexes; enzymatic techniques in steroid assay; mass fragmentography of steroid hormones; biological consequences of 18-hydroxylation; and steroidogenesis in adrenal cells. This text also explores the regulation of steroidogenesis in testis; androgen binding proteins in different testis compartments; nuclear acceptor sites for glucocorticoid receptors; estrogen receptors in the pancreas; and molecular mechanisms of steroid hormone action.

Pure and Applied Biology, Volume 3: Physical Properties of the Steroid Hormones illustrates the efficiency of methodology for the solution of problems of isolation, identification and quantitative determination of the physical properties of steroids. This volume is composed of five chapters, and begins with a survey of the factors that influence the partition coefficient of steroid hormone, along with the consideration of the types and preparation of solvent systems for determination. The next chapter describes the chromatographic mobilities of steroids using several chromatographic methods, such as paper chromatography. A chapter presents the ultraviolet absorption data on structural correlations of steroids. Another chapter highlights the conversion of a steroid into a fluorescent compound through the steroid-acid interaction mechanism. The final chapter deals with the selective absorption spectra of steroids in concentrated sulfuric acid without heating. This book is directed primarily toward steroid chemists and researchers.

reviews of the first edition -- `...this is an excellent, comprehensive book and can be highly recommended to those who want an up-to-date reference on steroid analysis.' Analyst