Symmetry Breaking In Cells And Tissues

“Symmetry Breaking in Cells and Tissues” presents a collection of seventeen reviews, opinions and original research papers contributed by theoreticians, physicists and mathematicians, as well as experimental biologists, united by a common interest in biological pattern formation and morphogenesis. The contributors discuss diverse manifestations of symmetry breaking in biology and showcase recent developments in experimental and theoretical approaches to biological morphogenesis and pattern formation on multiple scales.

“Symmetry Breaking in Cells and Tissues” presents a collection of seventeen reviews, opinions and original research papers contributed by theoreticians, physicists and mathematicians, as well as experimental biologists, united by a common interest in biological pattern formation and morphogenesis. The contributors discuss diverse manifestations of symmetry breaking in biology and showcase recent developments in experimental and theoretical approaches to biological morphogenesis and pattern formation on multiple scales.

In biology, symmetry breaking refers to the process of breaking of uniformity or reducing the number of points to view invariance in order to produce a more improbable and structured state. It occurs when symmetry with a specific axis is lost in order to create polarity. This polarity helps the biological system in differentiating between different poles along an axis. Cells must first establish polarity by a symmetry-breaking event, before organs and tissues become polar. The fact that symmetry breaking occurs at all scales reflects its importance in biology. It can be found at the subcellular level, macromolecular level, and even at the organ and tissue levels. This book provides significant information to help develop a good understanding of symmetry breaking in biology. It presents researches and studies performed by experts across the globe. Those in search of information to further their knowledge will be greatly assisted by this book.

Experts examine the mechanisms by which cells polarize, divide asymmetrically, and produce asymmetric structures, providing examples from bacteria, yeast, plants, invertebrates, and mammals. Discussion include the molecular basis of polarization, mechanisms, and more.

Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout

This book proposes the foundation of the relational approach to biology, rejecting the deterministic and reductionist approach of molecular biology. Although biology has made enormous progress in the last seventy years, onto genesis is still conceived as a “revelation” of information (DNA). Recovering the geometric tradition, relational biology conceives scientific and epistemological tools (cause, probability, space etc.) of science in a new way. If probabilistic biology and organicism still proposes a biology based on physics, with a fundamental invariant, relational biology is based on variation: its fundamental invariant is variation, one of the most important elements of life. This is an indispensable book for academics who consider biology from a new theoretical approach, in particular for those working in the domains of cancer, ontogenesis and evolution.

Cell Polarity in Development and Disease, Volume 154 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Cell polarity in the protist-to-animal transition, Polarized actin networks in development: Case studies from Drosophila, Protein clustering and cell polarization, Polarity in the Drosophila female germline, Context Matters: Mechanisms governing epithelial polarization in C. elegans, Epithelial polarity in the fly: Principles and diversity, Polarizing epithelial expulsion and expulsion driven by mispolarization, The Role of Apical-Basal Polarization in the Mammalian First Cell Fate Decision, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Cell Biology series Updated release includes the latest information on Cell Polarity in Development and Disease

Gradients and Tissue Patterning, Volume 137 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on gradients and tissue patterning