The Arctic Aeromedical Laboratory S Thyroid Function Study

During the 1950s, with the Cold War looming, military planners sought to know more about how to keep fighting forces fit and capable in the harsh Alaskan environment. In 1956 and 1957, the U.S. Air Force's former Arctic Aeromedical Laboratory conducted a study of the role of the thyroid in human acclimatization to cold. To measure thyroid function under various conditions, the researchers administered a radioactive medical trace, Iodine-131, to Alaska Natives and white military personnel; based on the study results, the researchers determined that the thyroid did not play a significant role in human acclimatization to cold. When this study of thyroid function was revisited at a 1993 conference on the Cold War legacy in the Arctic, serious questions were raised about the appropriateness of the activity--whether it posed risks to the people involved and whether the research had been conducted within the bounds of accepted guidelines for research using human participants. In particular, there was concern over the relatively large proportion of Alaska Natives used as subjects and whether they understood the nature of the study. This book evaluates the research in detail, looking at both the possible health effects of Iodine-131 administration in humans and the ethics of human subjects research. This book presents conclusions and recommendations and is a significant addition to the nation's current reevaluation of human radiation experiments conducted during the Cold War.

During the 1950s, with the Cold War looming, military planners sought to know more about how to keep fighting forces fit and capable in the harsh Alaskan environment. In 1956 and 1957, the U.S. Air Force's former Arctic Aeromedical Laboratory conducted a study of the role of the thyroid in human acclimatization to cold. To measure thyroid function under various conditions, the researchers administered a radioactive medical trace, Iodine-131, to Alaska Natives and white military personnel; based on the study results, the researchers determined that the thyroid did not play a significant role in human acclimatization to cold. When this study of thyroid function was revisited at a 1993 conference on the Cold War legacy in the Arctic, serious questions were raised about the appropriateness of the activityâ€"whether it posed risks to the people involved and whether the research had been conducted within the bounds of accepted guidelines for research using human participants. In particular, there was concern over the relatively large proportion of Alaska Natives used as subjects and whether they understood the nature of the study. This book evaluates the research in detail, looking at both the possible health effects of Iodine-131 administration in humans and the ethics of human subjects research. This book presents conclusions and recommendations and is a significant addition to the nation's current reevaluation of human radiation experiments conducted during the Cold War.

Explores the links between the Cold War and the global environment, ranging from the environmental impacts of nuclear weapons to the political repercussions of environmentalism.

Between 1945 and 1970, Canada’s Department of National Defence sponsored scientific research into the myriad challenges of military operations in cold regions. To understand and overcome the impediments of the country’s cold climate, scientists studied cold-weather acclimatization, hypothermia, frostbite, and psychological morale for soldiers assigned to active duty in northern Canada. Frontier Science investigates the history of military science in northern Canada during this period of the Cold War, highlighting the consequences of government-funded research for humans and nature alike. The book reveals how under the guise of “environmental protection” research, the Canadian military sprayed pesticides to clear bushed areas, used radioactive substances to investigate vector-borne diseases, pursued race-based theories of cold tolerance, and enabled wide-ranging tests of newly developed weapons and equipment. In arguing that military research in northern Canada was a product of the Cold War, Matthew S. Wiseman tackles questions of government power, scientific authority, and medical and environmental research ethics. Based on a long and deep pursuit of declassified records, archival sources, and oral testimony, Frontier Science is a fascinating new history of military approaches to the human-nature relationship.

This report is divided into three sections: (1) "openness in government", describes steps the Administration has taken to make government records of human radiation experiments readily available to the public; (2) "protecting future human subjects", sets forth the Administration's actions to strengthen the protection of human subjects; (3) "righting past wrongs", summarizes the Administration's efforts to notify the public and individuals about past human radiation experiments and bring justice to those affected by the government's mistakes. This report presents those actions that are completed or underway.

Paralleling emerging trends in cyber-health technology, concerns are mounting about racial and ethnic disparities in health care utilization and outcomes. This book brings these themes together, challenging readers to use, promote, and develop new technology-based methods for closing these gaps. Edited by a leading urban health advocate and featuring 16 expert contributors, the book examines cyber-strategies with the greatest potential toward effective, equitable care, improved service delivery and better health outcomes for all. The rise of e-Patients and the transformation of the doctor-patient relationship are also discussed.

Named an Outstanding Academic Title for 2009 byChoice! "[A] set of almost 70 essays, all well informed and many with attitude." Harold Shapiro, PhD Professor Emeritus and Professor of Economics and Public Affairs Princeton University, Former Chair, National Bioethics Advisory Board "This most noteworthy and authoritative collection of 67 essays...represents 'the Penn way of doing bioethics' ....The Penn Center is widely known for multidisciplinary scholarship that emphasizes empirical inquiry on bioethical issues coupled with practical application(s)....The book provides excellent coverage of...both classical topics (e.g., informed consent, infertility, eugenics) and emerging issues (e.g., cloning, nonprofessional caregiving, privacy of thought in the age of brain imaging). The contributors, including the three editors, are either well-established or emerging scholars. Each essay offers historical background, an overview of relevant issues, a conclusion, and a list of references....Summing Up: Highly recommended."--Choice: Current Reviews for Academic Libraries "This well-written book addresses a wide-ranging assortment of traditional bioethics issues that persist in the field as well as contemporary bioethics concerns that have evolved with new technologies and medical advances. This is a great resource for scholars in bioethics as well as various other relevant disciplines concerned with bioethical issues." Score: 96, 4 stars--Doody's Medical Reviews The Center for Bioethics at the University of Pennsylvania is the internationally recognized leader in bioethical education and research. Its interdisciplinary faculty is drawn from the fields of medicine, law, nursing, education, philosophy, psychology, and religious studies. Arthur L. Caplan, the Center's founding director, is recognized as one of the most influential experts in bioethics. He has authored numerous books and articles, and served as the Chair of the Advisory Committee to the United Nations on human cloning. The Penn Center's leading fellows, Autumn Fiester and Vardit Ravitsky, have combined their expertise with Dr. Caplan and over 80 other contributors to create The Penn Center Guide to Bioethics--the foremost authority on both traditional and cutting-edge bioethical issues. The Penn Guide navigates uncharted ethical terrains, undoubtedly shaping both academic and public discourses on the challenging controversies generated by new technologies, theories, and medical advances. This volume represents the Penn Center's distinct, pioneering approach to bioethics, one that emphasizes empirical treatment of bioethical issues, and the integration of bioethical scholarship with practical application. Learn what the Penn Center has to say about: Neuroethics and brain imaging: Is my mind mine? Choosing future people: reproductive technologies and identity Eugenics and survival of the fittest in the modern world Bioethics and national security Vaccination, abortion, nanotechnology, organ transplantation, end-of-life issues, and more The Penn Guide will be the definitive text for policy makers, health practitioners, researchers, and students. This book will also inform the general public, patients, and family members as they seek answers to the bioethical issues of the day.

This is a new treatment of clinical research ethics in an African context, and an indispensable resource for researchers, students, policy makers and research institutions interested in African research ethics. In re-appraising the African philosophical notion of selfhood, it argues for the need to re-conceptualize responsibility in clinical trials, pushing researchers to go beyond autonomy-based considerations based on the individual only, and to develop clinical trials that appropriately embed research subjects within their community and their environment. The African standpoint stresses communalism and communitarianism. As such, responsibility for, and by, the individual can only make sense through the community in which the individual is rooted. The book emphasizes the African viewpoint by making explicit the importance of the self in the re-contextualized arena of the community. It forces research ethicists to go beyond autonomy-based considerations for the individual only, and to appropriately embed research subjects within their community and their environment.