The Cox 2 Connection

In this innovative text, James LaValle clearly explains what can cause joint and muscle inflammation, then sets forward mutliple treatments, with step-by-step instructions on how to use these treatments most effectively. Futhermore, he writes about exciting new studies that indicate the possible effectiveness of Cox-2 inhibitors in treating diseases such as cancer and Alzheimer's.

Ergebnisse von in vitro-Studien lassen vermuten, dass sich der pH-Wert in einem Tumor auf die Wirksamkeit von Chemo- oder Strahlentherapien auswirken kann. Wie aber sieht die Beziehung zwischen der Tumorentwicklung und dem pH-Wert aus? Können ein niedriger pH-Wert oder ein Sauerstoffmangel die Carcinogenese hemmen? Wo bieten sich therapeutische Ansätze? Anwort auf diese und andere Fragen finden Sie in diesem Band. In interdisziplinärer Weise wurden Beiträge aus der Grundlagenforschung und der klinischen Praxis zusammengetragen.

Empowers women to make informed decisions about autoimmune disorders More than 50 million Americans, most of them women, suffer from a constellation of mysterious, often misdiagnosed diseases that can result in disability, disfigurement, and death. Called "autoimmune diseases," they arise when the immune system attacks healthy tissues in almost any area of the body, and include lupus rheumatoid arthritis, Crohn's disease, scleroderma, and Graves' disease. Now Jill Buyon, a doctor working on the cutting edge of research into these diseases, and Rita Baron-Faust, an award-winning medical journalist, arm women with the knowledge they need to obtain accurate diagnoses and the best possible treatments. In The Autoimmune Connection readers learn about the recent groundbreaking discovery of the links between the different autoimmune diseases and why women are more likely to develop them. The authors offer the most up-to-date information on diagnosis, treatments, and risks for women with one or more autoimmune disease.

COX-2 Inhibitors are newly developed drugs for inflammation that selectively block the COX-2 enzyme. Blocking this enzyme impedes the production of the chemical messengers (prostaglandins) that cause the pain and swelling of arthritis inflammation. Cox-2 inhibitors are a new class of nonsteroidal anti-inflammatory drugs (NSAIDS). Because they selectively block the Cox-2 enzyme and not the Cox-1 enzyme, these drugs are uniquely different from traditional NSAIDS. This book explores new research in this field.

Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders. This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants – including vitamin D, tocotrienol and coenzyme Q10 – against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection. Key Features: Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods. Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions. Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods. The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.

The information surveyed in this volulme is designed to provide the clinician with an expert overview of the current state of the art in breast cancer management. It should provide at least a flavor of the major paradigm shift that is occurring in this rapidly evolving field. Breast cancer management is moving away from a "kill or cure" model and advancing toward a model focused on strategies of prevention and of long-term management of breast cancer as a chronic disease. The acceptance of this new paradigm by patients and clinicians alike will represent a major focus for the twenty-first century.

You can breathe a little easier knowing there’s a proven way to master respiratory pharmacology! For over 30 years, Rau’s Respiratory Care Pharmacology has been considered the preeminent text on the subject. With easy to grasp terminology, relatable explanations, and reader-friendly writing, the 10th edition simplifies the process of learning pharmacology material like never before. As in previous editions, Rau’s is organized into three logical sections, covering the basics of respiratory care, frequently used drugs, and critical care medications. New to this edition is a Clinical Connections feature that helps you to connect lessons from the book with the clinical setting. Rau’s truly is the best source for preparing you for success on your exams and in professional practice! Learning objectives parallel the levels tested by the NBRC exams to help you to identify important information that goes beyond memorization and recall. Key terms with definitions provide easy access to the pharmacologic vocabulary you should embrace. Key points boxes in each chapter highlight important concepts in the lesson. Full-color design makes the text more reader-friendly and helps you to identify relevant details within an illustration. Self-assessment questions give you the opportunity to test yourself on content learned with thought-provoking questions that require short answers. Clinical scenarios with follow-up SOAP assessment help you to assess your comprehension of the material. Glossary of all key terms in the text aids you in understanding the terminology associated with respiratory care pharmacology. Appendices on common units, systems of measurement, and acceptable mixtures provides references to need-to-know information such as abbreviations, conversion charts for temperatures, liquid metric and solids, and a simple drug compatibility chart for drug mixtures. Alphabetical drug index offers a direct index to look up information based on drug name. NEW! Recently-approved FDA medications help familiarize you with current information. UPDATED All asthma (GINA & NAEPP) and COPD (Gold guidelines) protocols to the latest editions. UPDATED Enhanced readability helps you to more easily understand difficult material. NEW! Clinical Connection boxes helps you to connect what you’ve learned with the clinical setting.