The Graft Theory Of Disease Being An Application Of Mr Darwin S Hypothesis Of Pangenesis To The Explanation Of The Phenomena Of The Zymotic Diseases

Darwin’s Pangenesis and Its Rediscovery Part A highlights the findings of Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation that strengthened his theory of evolution and explained many phenomena of life. Now, new advances and the discovery of circulating cell-free DNA, mobile RNAs, prions and extracellular vesicles are providing new breakthroughs, thus increasing evidence on the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis suggests. Sections of note in this volume include the rationale, criticisms, influence and recent molecular evidence of Darwin's Pangenesis, as well as its relation to the inheritance of acquired characters, which is often included under the blanket term "transgenerational epigenetic inheritance." Presents a comprehensive approach to Darwin’s Pangenesis, which is so little understood that few have recognized its far-reaching importance, but seems today surprisingly modern Links Darwin's hypothetical gemmules with circulating cell-free DNA, mobile RNAs, prions and extracellular vesicles, shedding new light on an old theory Includes section on Darwin's Pangenesis in relation to the Lamarckian inheritance of acquired characters, a central debate in the history of genetics

Darwin’s Pangenesis and its Rediscovery Part B explores Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation from over 150 years ago that strengthened his theory of evolution and explained many phenomena of life. Now, new discoveries on circulating DNA, mobile RNAs, prions and extracellular vesicles are providing striking evidence for the chemical existence of Darwin’s imaginary gemmules. In addition, new evidence for the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis supposedly explains are progressing, and are hence explored in this comprehensive volume. Specific chapters in this new volume include Darwin and Mendel: The Historical Connection, Darwin’s Pangenesis and Graft Hybridization, Darwin’s Pangenesis and Medical Genetics, Darwin’s Pangenesis and Certain Anomalous Phenomena, and Natural Selection and Pangenesis: The Darwinian Synthesis. Presents the only book on Darwin’s Pangenesis, an expanded cell theory and a unified theory of heredity, variation, development and reproduction Highlights Darwin’s tremendous contributions to genetics, as well as Mendel’s legacy and limitations Includes sections on Darwin's Pangenesis in relation to graft hybridization, medical genetics, evolutionary theory, along with many other updates

During the surge of the deadliest and cruellest disease in history comes the unexpected encounter of two great men- one a pioneer of modern science, the other a pioneer of modern literature. In The Remedy, Thomas Goetz chronicles the riveting story of Robert Koch, a provincial doctor turned revolutionary scientist whose kitchen-sink discoveries inspired a new age of medicine - and ultimately aroused the interest and then the suspicion of another ambitious doctor, Arthur Conan Doyle. The account begins in 1875, when a diagnosis of tuberculosis or consumption, was a death sentence. Doctors had little in their arsenal for treating this cunning disease and were even less certain about what caused it. But a scientific revolution was brewing. Koch, armed with but a microscope and a notebook, began to methodically pursue these things called 'germs'. His biggest discovery - one that would push medicine out of the dark ages - was of the bacteria that caused tuberculosis. After the accolades and honors, Koch set his sights on a greater glory- not just to identify the cause but to create a cure. And then, he had it. When Koch announced his remedy for tuberculosis in 1890, euphoria swept the globe. Physician and aspiring writer Arthur Conan Doyle joined the throngs racing to Berlin for the public demonstration. But amid the frenzy over Koch's remedy, Conan Doyle quietly toured the wards of treated patients. He was staggered by what he found- Koch's remedy was either sloppy science or outright fraud. Conan Doyle has no choice but to accuse one of the world's greatest scientists of an unfathomable error. The question was this- Whom would the world believe? The Remedy, is a stunning tale of ambition and hubris, of discovery and deceit. It chronicles the profound shift in medical science from the nineteenth century of cod-liver oil and leeches to the twentieth century of microscopes and antibiotics. And it vividly explores how modern medicine emerges, not as the inevitable march of progress but as a lurching tumult of failed experiments and petty rivalries. In a brilliant interweaving of scientific and literary history, Goetz vividly shows that Koch and Conan Doyle shared more than a chance meeting- they were collaborators in the new age of medicine. What Koch proved in his laboratory Conan Doyle brought to the world through his literature - especially through his new scientific detective, Sherlock Holmes. As The Remedy makes clear, without Robert Koch, Sherlock Holmes would never have existed.