The Pancreas Its Surgery And Pathology

Excerpt from The Pancreas: Its Surgery and Pathology Our present knowledge of the physiology, pathology, and surgery of the pancreas, like so many other advances in medicine in recent years, was rendered possible by the beneficent work of Lister. So long as clinical observation was only capable of being checked by the experience of the post-mortem room, and by an occasional accidental experiment on the living subject, the important and complex part that the pancreas plays in the physiology of the body remained unsuspected, and descriptions of the diseases to which it is liable were confined to a few lines on malignant disease, cysts, and calculi. Animal experiments, now rendered safe by antiseptic surgery and improved technique, have thrown a flood of light on the physiology of the organ and elevated it from the position of a mere accessory digestive gland to the rank of a structure indispensable for the metabolic needs of the organism. The numerous laparotomies undertaken in recent years have afforded the surgeon opportunities of observing and handling the living organ, both in health and disease, and a comparison of the conditions noticed, together with a closer investigation of the symptoms and after-histories of the cases, has very, considerably widened our conception of the pathological changes that may occur in the gland and afforded a basis for their clinical differentiation. Histological and post-mortem inquiries, stimulated by the impetus thus given, have still further increased our knowledge, and confirmed the conclusions of the bedside and the operating theatre. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

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Excerpt from The Pancreas: Its Surgery and Pathology In the chapter on histology, and again later under the heading of diabetes, we have discussed the structure and supposed functions of those characteristic groups of cells known as the islands of Langerhans. In doing so we have endeavoured to impartially summarise the evidence for and against the contending views that are held with regard to them, but, as will be gathered from the text, we personally are of opinion that the balance of available evidence strongly points to their being independent struc tures related to the control of carbohydrate metabolism within the body that the pancreas undoubtedly exerts. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Exocrine pancreatic tumors of non-ductal origin: Acinar carcinoma, pancreatoblastoma and solid-pseudopapillary neoplasm; Pancreatic cystic tumors of mucinous type; Pancreatic cystic lesions of non-mucinous type; Pancreatic endocrine tumors; Inflammatory lesions and pseudotumors of the pancreas; Ductal adenocarcinoma of the pancreas; PanINs; Cytology of the Pancreas.

The pancreas is about the size and shape of the hand; the tail points to the spleen, and the head is nestled in a loop of the duodenum. Loss of the exocrine (digestive) func tions commonly leads to severe gastrointestinal disturbances, malabsorption, a cata bolic state, and weight loss in the face of an adequate diet. Loss of endocrine pancreatic function leads to a large spectrum of disorders associated with the loss of hormone secretions; the most common and most severe is diabetes mellitus. Loss of the entire pancreas owing to trauma, surgery, atherosclerosis, or other medical problems leaves the patient in a digestive and metabolic crisis. The correct diagnosis of pancreatic disorders remains a challenge given the multi faceted function of the pancreas. The clinical laboratory plays an important role, and other tools such as CAT scans, ultrasound, radiographs, biopsies, and even surgery are used to make a diagnosis. The emphasis of Clinical Pathology of Pancreatic Disorders is on the clinical laboratory definition of pancreatic pathology. Disorders of the endocrine pancreas can be highly complex, and sophisticated tests are needed to determine the nature of the disease, its prognosis, and its optimal treat ment. Diabetes is the most common of the endocrine diseases; it presents in many ways, and has varied etiologies. We now know that the diabetes of childhood is usually an autoimmune disease, and this has a major effect on the treatment of these individuals.

Derived from 40 years' experience in diagnostic surgical pathology and autopsy rooms, this book deals with the gross and microscopic structure of the normal pancreas, placing a special focus on structural abnormalities. Updated information on congenital abnormalities and the effects of primarily non-pancreatic diseases upon this organ such as arterial diseases, makes this new Second Edition a indispensable addition to your library.