The Practice Of Medicinal Chemistry 3 E
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The Practice Of Medicinal Chemistry 3 e
Author | : Wermuth |
Publsiher | : Unknown |
Total Pages | : 135 |
Release | : 2009-01-01 |
Genre | : Electronic Book |
ISBN | : 8131219615 |
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The Practice of Medicinal Chemistry
Author | : Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan |
Publsiher | : Elsevier |
Total Pages | : 903 |
Release | : 2015-07-01 |
Genre | : Science |
ISBN | : 9780124172135 |
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The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com
The Practice of Medicinal Chemistry
Author | : Camille Georges Wermuth |
Publsiher | : Academic Press |
Total Pages | : 982 |
Release | : 2011-05-02 |
Genre | : Medical |
ISBN | : 9780080568775 |
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The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry. NEW TO THIS EDITION: * Focus on chemoinformatics and drug discovery * Enhanced pedagogical features* New chapters including: - Drug absorption and transport - Multi-target drugs* Updates on hot new areas: NEW! Drug discovery and the latest techniques NEW! How potential drugs can move through the drug discovery/ development phases more quickly NEW! Chemoinformatics
The Practice of Medicinal Chemistry
Author | : Camille Georges Wermuth |
Publsiher | : Elsevier |
Total Pages | : 736 |
Release | : 2003-06-11 |
Genre | : Science |
ISBN | : 9780080497778 |
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The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. * The only book available dealing with the practical aspects of medicinal chemistry * Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production * Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry
The Handbook of Medicinal Chemistry
Author | : Andrew Davis,Simon E Ward |
Publsiher | : Royal Society of Chemistry |
Total Pages | : 753 |
Release | : 2015-07-07 |
Genre | : Science |
ISBN | : 9781782621836 |
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Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.
Comprehensive Medicinal Chemistry III
Author | : Anonim |
Publsiher | : Elsevier |
Total Pages | : 4609 |
Release | : 2017-06-03 |
Genre | : Technology & Engineering |
ISBN | : 9780128032015 |
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Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
The Handbook of Medicinal Chemistry Principles and Practice
Author | : Simon E Ward,Andrew Davis |
Publsiher | : Royal Society of Chemistry |
Total Pages | : 1051 |
Release | : 2023-02-03 |
Genre | : Medical |
ISBN | : 9781788018982 |
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The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparalleled insight into the field in a single, invaluable volume.
Comprehensive Medicinal Chemistry III
Author | : Samuel Chackalamannil,David Rotella,Simon Edward Ward,Ana Martinez,Carmen Gil,Helmut Buschmann,Norbert Handler,Andrea Wolkerstorfer,Andrew M. Davis,Colin Edge,Alan G. E. Wilson,Ian Collins,William Watkins,Louis J. Lombardo,Ved Srivastava,Adrian Hall,Santhosh Neelamkavil,Rob Jones,Jörg Holenz |
Publsiher | : Unknown |
Total Pages | : 610 |
Release | : 2017 |
Genre | : Electronic Book |
ISBN | : 0081022409 |
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