The Role Of Glia In Alzheimer S Disease
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The Role of Glia in Alzheimer s Disease
Author | : Beatriz G. Perez-Nievas,Alberto Serrano-Pozo |
Publsiher | : Frontiers Media SA |
Total Pages | : 128 |
Release | : 2019-03-20 |
Genre | : Electronic Book |
ISBN | : 9782889457649 |
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We believe that the role of glia is the next frontier to be explored in Alzheimer’s disease research. This eBook is an update on both the current knowledge of astrocytes and microglia involvement in Alzheimer’s disease pathophysiology, and some of the techniques available to study them.
Glia in Health and Disease
Author | : Tania Spohr |
Publsiher | : BoD – Books on Demand |
Total Pages | : 164 |
Release | : 2020-05-20 |
Genre | : Science |
ISBN | : 9781789852530 |
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The book will highlight the role played by glial cells in the central and peripheral nervous systems in both healthy and unhealthy individuals. Among all processes involved, we will discuss the importance of the enteric nervous system in the control of gut homeostasis, in the interaction with the immune system, and its participation in pathological conditions such as metabolic syndrome. We will also look at the relevance of astrocytes during synaptic transmission and the regulation of plasticity by releasing gliotransmitters. Ultimately, we will highlight the influence of astrocytes during the development of a number of neurodegenerative diseases, such as multiple sclerosis and Alzheimer’s disease, focusing on how the serum levels of the astrocytic protein S100B can be used as a biomarker for clinical decisions.
The Role of Glia in Neurotoxicity
Author | : Michael Aschner,Lucio G. Costa |
Publsiher | : CRC Press |
Total Pages | : 477 |
Release | : 2004-12-28 |
Genre | : Medical |
ISBN | : 9781420039740 |
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Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.
Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases
Author | : Tuan Leng Tay,Giuseppe Locatelli,Gabriela Constantin,V. Wee Yong |
Publsiher | : Frontiers Media SA |
Total Pages | : 259 |
Release | : 2022-05-03 |
Genre | : Medical |
ISBN | : 9782889760701 |
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The Biology of Glial Cells Recent Advances
Author | : Ishan Patro,Pankaj Seth,Nisha Patro,Prakash Narain Tandon |
Publsiher | : Springer Nature |
Total Pages | : 763 |
Release | : 2022-04-09 |
Genre | : Medical |
ISBN | : 9789811683138 |
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This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and diseases. It discusses the latest advances in understanding their origin, differentiation, and hemostasis. The book also examines the role of microglial cells in central nervous system (CNS) development, maintenance, and synaptic plasticity. Further, the book presents the functions of astrocytes in healthy CNS and their critical role in CNS disorders, including Parkinson's and Alzheimer's diseases. Notably, the book describes the pathobiology, molecular pathogenesis, stem cells, and imaging characteristics of gliomas. It defines the role of glial cells in regulating iron homeostasis and their effect on the neurodegeneration of neurons. Lastly, it covers the structure, function, and pathology of oligodendrocytes and their role in neuronal health and disease.
Role of Glial Cells of the Central and Peripheral Nervous System in the Pathogenesis of Neurodegenerative Disorders
Author | : Guanghui Wang,Gerald Muench,Yong-Jing Gao,Haigang Ren,Subashchandrabose Chinnathambi |
Publsiher | : Frontiers Media SA |
Total Pages | : 189 |
Release | : 2022-05-26 |
Genre | : Science |
ISBN | : 9782889762361 |
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Glial Cells in Health and Disease of the CNS
Author | : Rommy von Bernhardi |
Publsiher | : Springer |
Total Pages | : 348 |
Release | : 2016-10-06 |
Genre | : Medical |
ISBN | : 9783319407647 |
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A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.
Glia and Inflammation in Neurodegenerative Disease
Author | : M. A. Yenari,Rona Greenberg Giffard |
Publsiher | : Nova Science Publishers |
Total Pages | : 290 |
Release | : 2006 |
Genre | : Medical |
ISBN | : UVA:X030116408 |
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The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brain's resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.