The Role Of Ncrnas In Solid Tumors Prognosis From Laboratory To Clinical Utility
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The Role of ncRNAs in Solid Tumors Prognosis From Laboratory To Clinical Utility
Author | : Jian-Guo Zhou,Zhaohui Huang,Ondrej Slaby,Alfons Navarro |
Publsiher | : Frontiers Media SA |
Total Pages | : 599 |
Release | : 2021-03-23 |
Genre | : Medical |
ISBN | : 9782889666096 |
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Strategic Molecular Biomarkers and MicroRNAs in Cancer
Author | : César López-Camarillo,Ondrej Slaby,Macrina Beatriz Silva Cázares |
Publsiher | : Frontiers Media SA |
Total Pages | : 127 |
Release | : 2022-11-15 |
Genre | : Medical |
ISBN | : 9782832506004 |
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Genetic and proteomic biomarkers in solid tumor detection and treatment
Author | : Jitian Li,Apeng Chen,Ruowen Zhang,Changwei Li,Jian-Guo Zhou |
Publsiher | : Frontiers Media SA |
Total Pages | : 862 |
Release | : 2023-06-07 |
Genre | : Science |
ISBN | : 9782832525456 |
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Drug Resistance in Colorectal Cancer Molecular Mechanisms and Therapeutic Strategies
Author | : Chi Hin Cho,Tao Hu |
Publsiher | : Academic Press |
Total Pages | : 242 |
Release | : 2020-05-24 |
Genre | : Science |
ISBN | : 9780128199381 |
Download Drug Resistance in Colorectal Cancer Molecular Mechanisms and Therapeutic Strategies Book in PDF, Epub and Kindle
Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer. Presents a systemic summary of molecular mechanisms for a quick and in-depth understanding Updates current trends in the field with pioneering information on drug resistance Encompasses both basic and clinical approaches for a better understanding of unsolved problems from a holistic point-of-view
Advances in the Molecular Understanding of Colorectal Cancer
Author | : Eva Segelov |
Publsiher | : BoD – Books on Demand |
Total Pages | : 174 |
Release | : 2019-02-06 |
Genre | : Medical |
ISBN | : 9781789850598 |
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An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early. This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular techniques and the ability to correlate molecular changes with clinical behaviour of tumours. Each chapter is a summary written by experts, concisely summarising current data as well as highlighting potential areas for advancement. Appreciating the differences between tumours on a molecular level is the key to developing and delivering precision medicine, and nowhere is this more critically required than in the field of colorectal cancer.
Precision Cancer Medicine
Author | : Sameek Roychowdhury,Eliezer M. Van Allen |
Publsiher | : Springer Nature |
Total Pages | : 196 |
Release | : 2020-01-02 |
Genre | : Medical |
ISBN | : 9783030236373 |
Download Precision Cancer Medicine Book in PDF, Epub and Kindle
Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology, computational biology, clinical oncology, cancer biology, drug development, genetics, immunology, and bioethics. Thus, we have outlined a current text on each of these fields as they work together to overcome various challenges and create opportunities to deliver precision cancer medicine. As trainees and junior faculty enter their respective fields, this text will provide a framework for understanding the role and responsibility for each specialist to contribute to this team science approach.
Neuroblastoma
Author | : Chandrika Gowda |
Publsiher | : BoD – Books on Demand |
Total Pages | : 169 |
Release | : 2017-10-25 |
Genre | : Medical |
ISBN | : 9789535135838 |
Download Neuroblastoma Book in PDF, Epub and Kindle
Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma.
Epigenetic Therapy of Cancer
Author | : Michael Lübbert,Peter A. Jones |
Publsiher | : Springer Science & Business Media |
Total Pages | : 332 |
Release | : 2013-12-12 |
Genre | : Medical |
ISBN | : 9783642384042 |
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The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders is now being translated into treatment approaches that target the epigenetic defects pharmacologically. This book first presents the latest evidence regarding the epigenetic regulation of hematopoietic stem cell differentiation and hemoglobin production. The significance of DNA methylation abnormalities in hematopoietic disorders and of epigenetic disturbances in lung cancer and other solid tumors is then discussed. A major part of the book, however, relates specifically to the translation of basic research and drug development to clinical applications, and in this context both present and future clinical strategies are considered. Individual chapters are devoted to the use of DNA hypomethylating agents and chromatin-modifying agents, and the treatment of hematologic malignancies and solid tumors by means of epigenetic agents is discussed in detail.