The Statistical Evaluation Of Medical Tests For Classification And Prediction
Download The Statistical Evaluation Of Medical Tests For Classification And Prediction full books in PDF, epub, and Kindle. Read online free The Statistical Evaluation Of Medical Tests For Classification And Prediction ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
The Statistical Evaluation of Medical Tests for Classification and Prediction
Author | : Margaret Sullivan Pepe |
Publsiher | : OUP Oxford |
Total Pages | : 319 |
Release | : 2003-03-13 |
Genre | : Medical |
ISBN | : 9780191588617 |
Download The Statistical Evaluation of Medical Tests for Classification and Prediction Book in PDF, Epub and Kindle
This book describes statistical techniques for the design and evaluation of research studies on medical diagnostic tests, screening tests, biomarkers and new technologies for classification and prediction in medicine.
The Statistical Evaluation of Medical Tests for Classification and Prediction
Author | : Margaret Sullivan Pepe |
Publsiher | : Unknown |
Total Pages | : 319 |
Release | : 2003 |
Genre | : Biochemical markers |
ISBN | : 9780198509844 |
Download The Statistical Evaluation of Medical Tests for Classification and Prediction Book in PDF, Epub and Kindle
This book describes statistical concepts and techniques for evaluating medical diagnostic tests and biomarkers for detecting disease. More generally, the techniques pertain to the statistical classification problem for predicting a dichotomous outcome. Measures for quantifying test accuracy are described including sensitivity, specificity, predictive values, diagnostic likelihood ratios and the Receiver Operating Characteristic Curve that is commonly used for continuous and ordinal valued tests. Statistical procedures are presented for estimating and comparing them. Regression frameworks for assessing factors that influence test accuracy and for comparing tests while adjusting for such factors are presented. This book presents many worked examples of real data and should be of interest to practicing statisticians or quantitative researchers involved in the development of tests for classification or prediction in medicine.
Statistical Methods in Diagnostic Medicine
Author | : Xiao-Hua Zhou,Nancy A. Obuchowski,Donna K. McClish |
Publsiher | : John Wiley & Sons |
Total Pages | : 597 |
Release | : 2014-08-21 |
Genre | : Medical |
ISBN | : 9781118626047 |
Download Statistical Methods in Diagnostic Medicine Book in PDF, Epub and Kindle
Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.
Fundamentals of Clinical Data Science
Author | : Pieter Kubben,Michel Dumontier,Andre Dekker |
Publsiher | : Springer |
Total Pages | : 219 |
Release | : 2018-12-21 |
Genre | : Medical |
ISBN | : 9783319997131 |
Download Fundamentals of Clinical Data Science Book in PDF, Epub and Kindle
This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience.
Topics in Biostatistics
Author | : Walter T. Ambrosius |
Publsiher | : Springer Science & Business Media |
Total Pages | : 530 |
Release | : 2007-07-06 |
Genre | : Medical |
ISBN | : 9781588295316 |
Download Topics in Biostatistics Book in PDF, Epub and Kindle
This book presents a multidisciplinary survey of biostatics methods, each illustrated with hands-on examples. It introduces advanced methods in statistics, including how to choose and work with statistical packages. Specific topics of interest include microarray analysis, missing data techniques, power and sample size, statistical methods in genetics. The book is an essential resource for researchers at every level of their career.
Statistical Evaluation of Diagnostic Performance
Author | : Kelly H. Zou,Aiyi Liu,Andriy I. Bandos,Lucila Ohno-Machado,Howard E. Rockette |
Publsiher | : CRC Press |
Total Pages | : 243 |
Release | : 2016-04-19 |
Genre | : Mathematics |
ISBN | : 9781439812235 |
Download Statistical Evaluation of Diagnostic Performance Book in PDF, Epub and Kindle
Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents innovative approaches in ROC analysis, which are releva
Principles and Practice of Clinical Trials
Author | : Steven Piantadosi,Curtis L. Meinert |
Publsiher | : Springer Nature |
Total Pages | : 2573 |
Release | : 2022-07-19 |
Genre | : Medical |
ISBN | : 9783319526362 |
Download Principles and Practice of Clinical Trials Book in PDF, Epub and Kindle
This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.
Regression Modeling Strategies
Author | : Frank E. Harrell |
Publsiher | : Springer Science & Business Media |
Total Pages | : 583 |
Release | : 2013-03-09 |
Genre | : Mathematics |
ISBN | : 9781475734621 |
Download Regression Modeling Strategies Book in PDF, Epub and Kindle
Many texts are excellent sources of knowledge about individual statistical tools, but the art of data analysis is about choosing and using multiple tools. Instead of presenting isolated techniques, this text emphasizes problem solving strategies that address the many issues arising when developing multivariable models using real data and not standard textbook examples. It includes imputation methods for dealing with missing data effectively, methods for dealing with nonlinear relationships and for making the estimation of transformations a formal part of the modeling process, methods for dealing with "too many variables to analyze and not enough observations," and powerful model validation techniques based on the bootstrap. This text realistically deals with model uncertainty and its effects on inference to achieve "safe data mining".