The Surgery Of Childhood Tumors

Beginning with the scientific basis of tumors, this book provides up-to-date information on epidemiology, cytogenetics, and molecular biology, before examining current treatments for the full range of pediatric tumors. Integration of surgery, neoadjuvant and adjuvant chemotherapy, and radiation therapy is a dominant theme. In addition, chapters on supportive care, palliative care, and the role of parents’ associations reflect the book's holistic approach. All chapters are written by world-renowned international authorities on pediatric cancer from major children's cancer groups. Excellent full-color pictures and line drawings illustrate all aspects of managing childhood tumors, including details of operative techniques neglected in many other texts. This comprehensive book, expanded and updated to encompass the very latest developments and strategies, provides a contemporary approach for pediatric, general, and urological surgeons dealing with childhood tumors.

Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

A new, definitive, state-of-the-art reference in the specialist field of paediatric surgical oncology. Key points and informative guidance on all aspects of cancer surgery for children make this a vital textbook for the surgery resident, surgical oncology specialist, nursing staff and cancer health care teams. The editorial team of world experts and international guest authorship listings guarantees that the textbook content provides a definitive treatise for a global audience of pediatric surgeons. Textbook coverage includes chapters on pediatric cancer epidemiology, chemotherapy, immunotherapy, radiotherapy, pathology, radiology and vascular access, following which the main theme sections feature all of the major pediatric solid tumours in a system-based chronology. A section devoted to rare tumours provides useful and pragmatic information for the oncology surgeon. Minimally invasive surgery is covered highlighting current concepts and clinical outcome(s) by leading experts in the field. Nutritional considerations for the pediatric cancer patient undergoing surgery are all discussed. Management of surgical complications, fertility considerations and long-term outcomes are an invaluable vital resource for the reader. Final sections "look to the future" by focusing on surgical innovation, including key chapters on navigational surgery and surgical robotics. • Includes all the latest developments in pediatric surgical oncology ensuring the reader is kept fully up to date. • Multi-disciplinary content reflects current best practice. • Comprehensive coverage provides a definitive reference guide. An authoritative seminal reference work for surgical residents in training, surgeons working in the field of pediatric oncology, medical oncologists, intensive care specialists, nursing staff and allied health care professionals.

Edited by two leading childhood cancer specialists, and with contributions from authoritative experts in the field, this comprehensive reference covers all aspects of major childhood cancers including molecular oncology and translational therapy, pathological evaluation of childhood cancer, surgical management of pediatric tumors, non-hodgkin's lymphoma and lymphoproliferative disorders in children, infant brain tumors, prevention, diagnosis and treatment of infectious complications, pain management, late effects of childhood cancer therapy.

Childhood cancer was almost always fatal before 1970. Today, 80% of ch- dren diagnosed with cancer will survive at least 5 years; 70% will be cured. However, cancer continues to be the leading cause of nonaccident-related deaths in children. More children die each year from cancer than from c- tic ?brosis, diabetes, asthma, AIDS, and congenital abnormalities combined. Nine children die from cancer every school day. Despite the fact that pediatric cancers account for only a small p- centage of the total cancer burden, more effective therapies are needed to improve mortality rates in children. Therefore, our research priority must be the development of new agents and new therapies for childhood cancer. M. D. Anderson Cancer Center has been caring for children with c- cer since its doors opened over 60 years ago. This institution has been home to several research and clinical pioneers whose innovative work has in?uenced and shaped the practice of pediatric oncology throughout the world. Notably, Drs. Wataru W. Sutow, Donald Pinkel, and Norman Jaffe have been credited with introducing curative therapies for children with leukemia and solid tumors. Cancer treatment involves far more than administering chemoth- apy and surgically excising tumors. It requires a multidisciplinary - proach to patient management, particularly in the treatment of solid - mors, which pose the biggest challenge in cancer care today. Surgery and radiotherapy as well as radiographic and pathologic assessments of response are critical factors in the treatment of children with cancer.

This volume is devoted to the overall management of solid tumors in children. Recent advances in the use of monoclonal antibodies for diagnosis and possible treatment are presented. New approaches to the complete care of the child and family as well as specific developments in the treatment of defined conditions are discussed. A particular contribution deals with congential dysplasia of soft tissue. The material analyzed for this topic was taken from a unique collections of clinical cases supplemented by detailed laboratory studies.

Children with brain and spinal tumors account for 20-25% of childhood cancers. Until the early 1990s there had been little progress in the development of new treatments, and outcomes were not improving despite advances seen in other childhood cancers. During the past 10 years, however, there has been a dramatic increase in interest in the subject a

This issue of Surgical Oncology Clinics, guest edited by Dr. Roshni Dasgupta, is devoted to Pediatric Cancer. Dr. Dasgupta has assembled expert authors to review the following topics: Management of Neuroendocrine Cancer and GIST in Pediatric Patients; Management of Thyroid Tumors in Pediatric Patients; Management of Liver Tumors in Pediatric Patients; Management of Renal Tumors in Pediatric Patients; Management of Rhabdomyosarcoma in Pediatric Patients; Management of non-Rhabdomyosarcoma Soft Tissues Tumors in Pediatric Patients; Management of Melanoma and Skin Cancer in Pediatric Patients; Management of Lung Metastases in Pediatric Patients; Management of Adrenal Tumors in Pediatric Patients; Minimally Invasive Surgery and New Techniques in Pediatric Cancer Patients; Fertility Considerations and the Pediatric Cancer Patient; Management of Neuroblastoma in Pediatric Patients; Management of Germ Cell Tumors in Pediatric Patients; and more!