Third Opinion On Prostate Cancer

Hospitals and private clinics who rely on pathology reports must take responsibility for their negligence and disclose the third party mistakes that have caused their patients a lifetime of suffering. This book will convince you to take the extra time to get more than one opinion about your cancer diagnosis.This book is packed with research, interviews, and statistics related to prostate cancer. It describes how the author endured the false alarm of being misdiagnosed with Gleason 8 prostate cancer by four different pathologists and two different laboratories. This book is a must-read for anyone who is concerned about or who has been diagnosed with prostate cancer. Even if you are in the middle of any type of treatment, this book will increase your awareness about lifesaving issues. It will be your crash course on everything you need to know about prostate health and equip you with the knowledge you need to communicate effectively with your urologist and pathologist.

The minute that your urologist tells you that your biopsy is positive for prostate cancer, don't panic. I have been there and that is why this book is written. Here are ten facts: 1. Identifying cancerous cells in a biopsy of prostate gland is more difficult than identifying any other cancerous cells in biopsies of any other organs. 2. Laboratories often make mistakes, especially the laboratory that determined I had prostate cancer when I really did not. 3. Elevated PSA and MRI scanning is not accurate to determine prostate cancer, especially if you have an infection that elevates PSA. 4. If you ask your physician that you need to get a second opinion, s/he would refer you to urologists in his/her circle, locally. More than likely, the second opinion will confirm the first opinion of the primary physician. 5. In any surgery, especially prostate cancer surgery, you need to get additional two opinions, and the third one must be out of the state that you reside. 6. Believe it or not, a certain number of surgeons that remove prostate glands do this as a business to make money but careless about your health. 7. After the surgery, you will never know if your prostate was or was not really cancerous. Why? Because the gland is sent to the laboratory to determine that. But if the results are negative, it is too late. The system is rigged. 8. Even if you have prostate cancer, you need to get three (3) opinions as to the procedure. Don't settle for less. 9. Interview both urologist and the surgeon if all three (3) opinions are confirming you have prostate cancer. 10. It is your body and your prostate, read this book before making a drastic decision.

The minute that your urologist tells you that your biopsy is positive for prostate cancer, don't panic. I have been there and that is why this book is written. Here are ten facts: 1. Identifying cancerous cells in a biopsy of prostate gland is more difficult than identifying any other cancerous cells in biopsies of any other organs. 2. Laboratories often make mistakes, especially the laboratory that determined I had prostate cancer when I really did not. 3. Elevated PSA and MRI scanning is not accurate to determine prostate cancer, especially if you have an infection that elevates PSA. 4. If you ask your physician that you need to get a second opinion, s/he would refer you to urologists in his/her circle, locally. More than likely, the second opinion will confirm the first opinion of the primary physician. 5. In any surgery, especially prostate cancer surgery, you need to get additional two opinions, and the third one must be out of the state that you reside. 6. Believe it or not, a certain number of surgeons that remove prostate glands do this as a business to make money but careless about your health. 7. After the surgery, you will never know if your prostate was or was not really cancerous. Why? Because the gland is sent to the laboratory to determine that. But if the results are negative, it is too late. The system is rigged. 8. Even if you have prostate cancer, you need to get three (3) opinions as to the procedure. Don't settle for less. 9. Interview both urologist and the surgeon if all three (3) opinions are confirming you have prostate cancer. 10. It is your body and your prostate, read this book before making a drastic decision.

Although much progress has been made in the four years since the first edition of Management of Prostate Cancer, prostate cancer remains a significant biological, me- cal, and personal challenge for millions of men. In this interval, some important trends and observations have emerged that represent real progress in the field and which will shape the direction of clinical practice and research in the next 5–10 years. These obs- vations include: (1) a decline in prostate-related cancer mortality in the United States, likely owing to a combination of factors including screening, more aggressive and earlier therapy, and improvements in specific therapies; (2) a significant downward pathological stage migration, so that an individual’s chance of cure for a given stage, grade, and PSA is better now than it was early in the PSA era, even without associated improvements in individual therapies; (3) the recognition of new PSA isoforms that may refine screening strategies; (4) several randomized, phase III clinical trials demonstrating survival adv- tages of one form of therapy over another in selected populations (external beam rad- therapy with adjuvant hormones vs radiotherapy alone, radical prostatectomy vs observation); (5) a focus on the biology of bone and bone metastasis, and new agents that reduce skeletal-related events and which may inhibit the growth of new metastases; (6) second-generation anti-PSMA antibodies with improved potential for imaging and therapy; (7) the development and widespread adoption of nomograms that assist in cli- cal decision-making for individual patients; (8) the identification of new genes that

The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.

This book comprehensively covers application of salvage therapy in reccurrent prostate cancer. Chapters focus on specific issues associated with a range of surgical and oncological management techniques and strategies including hormone therapy, lymphnode dissection, robotic prostatectomy and salvage reirradiation after locoregional failure. Learning objectives, and definitions of keywords are provided to aid the reader develop a thorough understanding of the topic and reinforce the key points covered in each chapter. Salvage Therapy for Prostate Cancer provides a detailed practically applicable guide on how salvage therapy can be utilised in the treatment of prostate cancer. It represents a valuable resource for trainee and practicing urologists, oncologists, and specialist nurses.

Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts. Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies. Prostate Cancer: A Comprehensive Perspective, is a valuable and timely resource for urologists and oncologists.