Transplantation Immunology Research Trends
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Transplantation Immunology Research Trends
Author | : Oliver N. Ulricker |
Publsiher | : Nova Publishers |
Total Pages | : 278 |
Release | : 2007 |
Genre | : Transplantation immunology |
ISBN | : 1600215785 |
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In recent years, transplantation immunology has evolved as a distinct field founded on the recognition that rejection of a transplanted organ or tissue is mediated by immune mechanisms in the host responding to antigens in the donor tissue. Included within the scope are T cell immunity; Antigen presentation; Alloreactivity; Pancreas and islet cell transplantation; Allogeneic bone marrow transplantation Models of tolerance induction; Xenotransplantation and The swine leukocyte antigen (SLA) complex. This book gathers the latest research in the exciting new field of transplantation immunology.
Clinical Xenotransplantation
Author | : David K. C. Cooper,Guerard Byrne |
Publsiher | : Springer Nature |
Total Pages | : 313 |
Release | : 2020-09-08 |
Genre | : Medical |
ISBN | : 9783030491277 |
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This title provides an illuminating examination of the current state of xenotransplantation – grafting or transplanting organs or tissues between members of different species – and how it might move forward into the clinic. To be sure, this is a critical topic, as a major problem that remains worldwide is an inadequate supply of organs from deceased human donors, severely limiting the number of organ transplants that can be performed each year. Based on presentations given at a major conference on xenotransplantation, this title includes important views from many leading experts who were invited to present their data and opinions on how xenotransplantation can advance into the clinic. Attention was concentrated on pig kidney and heart transplantation as it is in regard to these organs that most progress has been made. Collectively, these chapters effectively highlight the many advantages of xenotransplantation to patients with end-stage organ failure, thereby encouraging the mapping of a concrete pathway to clinical xenotransplantation. The book is organized across 22 chapters, beginning with background information on clinical and experimental xenotransplantation. Following this are discussions addressing how pigs can be genetically engineered for their organs to be resistant to the human immune response through deletion of pig xenoantigens, and the insertion of ‘protective’ human transgenes. Subsequent chapters analyze complications that arise in practice, comparing allotransplant and xenotransplant rejection. The selection of the ideal patients for the first clinical trials is discussed. Finally, the book concludes with an analysis on the regulatory, economic, and social aspects of this research, including FDA perspectives and the sensitive, psychosocial factors regarding allotransplantation and xenotransplantation. A major and timely addition to the literature, Clinical Xenotransplantation will be of great interest to all researchers, physicians, and academics from other disciplines with an interest in xenotransplantation.
Transplantation of Marginal Organs Immunological Aspects and Therapeutic Perspectives
Author | : Caner Süsal,Christophe Legendre,Thomas Friedrich Mueller,Peter Schemmer |
Publsiher | : Frontiers Media SA |
Total Pages | : 183 |
Release | : 2020-12-28 |
Genre | : Medical |
ISBN | : 9782889662876 |
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Immunomodulation of Innate Immune Cells
Author | : Catarina R. Almeida,Barbara Bottazzi,Kate E. Lawlor,Dominic De Nardo |
Publsiher | : Frontiers Media SA |
Total Pages | : 204 |
Release | : 2020-03-23 |
Genre | : Electronic Book |
ISBN | : 9782889635740 |
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Advances in The Immunology of Host Defense Peptide Mechanisms and Applications of Antimicrobial Functions and Beyond
Author | : Mark Hulett,Charles Lee Bevins,Thanh Kha Phan |
Publsiher | : Frontiers Media SA |
Total Pages | : 399 |
Release | : 2021-04-07 |
Genre | : Medical |
ISBN | : 9782889666676 |
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Orchestration of an Immune Response to Respiratory Pathogens
Author | : Andrea Sant,Steven Varga |
Publsiher | : Frontiers Media SA |
Total Pages | : 183 |
Release | : 2019-07-25 |
Genre | : Electronic Book |
ISBN | : 9782889458844 |
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Transplantation Immunology
Author | : Philip Hornick |
Publsiher | : Springer Science & Business Media |
Total Pages | : 430 |
Release | : 2008-02-05 |
Genre | : Medical |
ISBN | : 9781597450492 |
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Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.
List of Journals Indexed for MEDLINE
Author | : Anonim |
Publsiher | : Unknown |
Total Pages | : 380 |
Release | : 2005 |
Genre | : Life sciences |
ISBN | : UOM:39015060289017 |
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