Two Sisters And A Brain Tumour

Thomas Clarkson was the son of a clergyman who lived in a time when it was legal to buy and sell slaves. He believed this was wrong, and campaigned to make sure this changed. He was instrumental in making sure that no human being could be bought or sold in the British Empire.

Heredity, environment, the role of infectious agents, and other influences have been cited within a multiplicity of factors of possible relevance to the problem of neoplasm etiology. In some cases, such as that of retinoblastoma the influence of hereditary factors has been clearly established. The influence of genetic factors in cerebral tumour development has been under discussion since as early as 1896 when Besold reported two sisters suffering from brain tumours. Although much more is now known about the classification, prognosis, and treatment of these tumours, and a number of familial cases have been reported, the present data are insufficient to permit conclusions regarding the influence of hereditary factors in the etiology of most types of cerebral neoplasms, and research in this area is urgently required. Research on familial brain tumours must still be largely based upon the cumulative case histories which have been reported. Although a number of papers contain historical reviews, some in tabulated form, the actual data have not been readily available to the researcher, each investigator being obliged to compile anew all reports published on the subject over an 80 year period. This book represents an attempt by the present authors to assemble the pertinent data on individual cases of familial brain tumours published since 1896. For this purpose the essential information from the original articles in German, French, Dutch, Spanish, Italian, Polish, and Czechoslovakian have been translated into English.

The report which follows constitutes the proceedings of a sym posium on the classification of brain tumours held in Cologne in 1961. It contains the contributions and discussions reported as far' as possible in a word-for-word manner, in the hope not only of providing out of the thoughts of the participants stimulation for further research, but also to indicate the atmosphere which prevailed during the symposium in which many completely opposed views were able to be expressed without any feeling of embarrassment. This freedom of expression is already obvious in the discussion of a proposed classification of brain tumours for the Unio Internationalis Contra Cancrum (UICC). The symposium endeavoured here to pro duce a positive criticism in order to arrive at a significant and practical conclusion viz a general, internationally acceptable classi fication. It was necessary to accept a degree of compromise even if the classification suggested did not in every point correspond to all the personal views of the various participants. The second part of the symposium was concerned with a critical discussion of numerous brain tumour problems, for example the scientific delineation of tumour groups; the discussion was started by general reviews on the biology of brain tumours so that the later discussion could cover as wide a ground as possibly. Here also we all felt that a great stimulus for future work arose from the discussion.

The International Meeting on Brain Oncology in Rennes was organised in honor of Jean Pecker, to pay tribute to his contribution to the development of neurological sciences and to take stock of the current state of knowledge on brain tumors, a domain in which the role of neurosurgery has been and will continue to be primordial. During the two-day conference, the major themes of brain oncology studies, both fundamental and clinical, were examined: oncogenesis, tumoral markers and immunology, metabolic and diagnosis imaging, prognostic factors and therapeutic strategies. The large number and high quality of participations resulted in a genuinely synthetic view of current advances in research, of which this book presents the essentials. We have attempted both to preserve the richness of scientific exchanges which occurred and to publish a great many oral and poster communications. The book respects the organization of conference sessions, and thus reflects the importance accorded to glial tumor studies. This may seem disproportionate given their frequency of occurrence in proportion to total numbers of intracranial tumor processes, but their gravity and quasi-total resistance to current therapeutic methods are ample justification. Moreover, this is the domain in which hopes of progress are beginning to appear, and it is becoming possible to envisage treatment based on recently established fundamental knowledge.

Themelios is an international, evangelical, peer-reviewed theological journal that expounds and defends the historic Christian faith. Themelios is published three times a year online at The Gospel Coalition (http://thegospelcoalition.org/themelios/) and in print by Wipf and Stock. Its primary audience is theological students and pastors, though scholars read it as well. Themelios began in 1975 and was operated by RTSF/UCCF in the UK, and it became a digital journal operated by The Gospel Coalition in 2008. The editorial team draws participants from across the globe as editors, essayists, and reviewers. General Editor: Brian Tabb, Bethlehem College and Seminary Contributing Editor: D. A. Carson, Trinity Evangelical Divinity School Consulting Editor: Michael J. Ovey, Oak Hill Theological College Administrator: Andrew David Naselli, Bethlehem College and Seminary Book Review Editors: Jerry Hwang, Singapore Bible College; Alan Thompson, Sydney Missionary & Bible College; Nathan A. Finn, Southeastern Baptist Theological Seminary; Hans Madueme, Covenant College; Dane Ortlund, Crossway; Jason Sexton, Golden Gate Baptist Seminary Editorial Board: Gerald Bray, Beeson Divinity School Lee Gatiss, Wales Evangelical School of Theology Paul Helseth, University of Northwestern, St. Paul Paul House, Beeson Divinity School Ken Magnuson, The Southern Baptist Theological Seminary Jonathan Pennington, The Southern Baptist Theological Seminary James Robson, Wycliffe Hall Mark D. Thompson, Moore Theological College Paul Williamson, Moore Theological College Stephen Witmer, Pepperell Christian Fellowship Robert Yarbrough, Covenant Seminary

In the tradition of My Stroke of Insight and Brain on Fire, this powerful memoir recounts Barbara Lipska's deadly brain cancer and explains its unforgettable lessons about the brain and mind. Neuroscientist Lipska was diagnosed early in 2015 with metastatic melanoma in her brain's frontal lobe. As the cancer progressed and was treated, she experienced behavioral and cognitive symptoms connected to a range of mental disorders, including dementia and her professional specialty, schizophrenia. Lipska's family and associates were alarmed by the changes in her behavior, which she failed to acknowledge herself. Gradually, after a course of immunotherapy, Lipska returned to normal functioning, amazingly recalled her experience, and through her knowledge of neuroscience identified the ways in which her brain changed during treatment. Lipska admits her condition was unusual; after recovery she was able to return to her research and resume her athletic training and compete in a triathalon. Most patients with similar brain cancers rarely survive to describe their ordeal. Lipska's memoir, coauthored with journalist Elaine McArdle, shows that strength and courage but also an encouraging support network are vital to recovery.

#1 NEW YORK TIMES BESTSELLER • “Bestselling author [Kristin] Hannah [brings] snap and a lot of warmth to a familiar lesson: that contentment comes from accepting each other’s flaws.”—People Years ago, Meghann Dontess made a terrible choice that cost her everything, including the love of her sister, Claire. Now, Meghann is a highly successful attorney who doesn’t believe in intimacy—until she meets the one man who can change her mind. Claire Cavenaugh has fallen in love for the first time in her life. As her wedding day approaches, she prepares to face her strong-willed older sister. Reunited after more than two decades apart, these two women who believe they have nothing in common will try to become what they never were: a family. Tender, funny, bittersweet, and moving, Between Sisters skillfully explores the profound joys and sorrows shared by sisters, the mistakes made in the name of love, and the promise of redemption—all beautifully told by acclaimed author Kristin Hannah. “Enormously entertaining . . . Hannah has a nice ear for dialogue and a knack for getting the reader inside the characters’ heads.”—The Seattle Times “Hannah writes of love with compassion and conviction.”—Luanne Rice