3d Modelling Of Mammalian Embryos And Organs
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3D Modelling of Mammalian Embryos and Organs
Author | : Silvia Garagna,Juan Aréchaga,Elisa Cebral,Maurizio Zuccotti |
Publsiher | : Frontiers Media SA |
Total Pages | : 188 |
Release | : 2021-11-08 |
Genre | : Science |
ISBN | : 9782889716074 |
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Examining the State of the Science of Mammalian Embryo Model Systems
Author | : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy |
Publsiher | : National Academies Press |
Total Pages | : 155 |
Release | : 2020-08-31 |
Genre | : Medical |
ISBN | : 9780309676687 |
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Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.
Mechanisms of Cellular Differentiation Organ Development and Novel Model Systems
Author | : Benedetta Artegiani,Delilah Hendriks,Kai Kretzschmar |
Publsiher | : Frontiers Media SA |
Total Pages | : 383 |
Release | : 2022-09-29 |
Genre | : Science |
ISBN | : 9782832501191 |
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Examining the State of the Science of Mammalian Embryo Model Systems
Author | : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy |
Publsiher | : National Academies Press |
Total Pages | : 155 |
Release | : 2020-07-31 |
Genre | : Medical |
ISBN | : 9780309676717 |
Download Examining the State of the Science of Mammalian Embryo Model Systems Book in PDF, Epub and Kindle
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.
Contemporary Models in Ectodermal Organ Development Maintenance and Regeneration
Author | : Isabelle Miletich,Abigail Saffron Tucker,Maisa Hanna-Maija Seppala |
Publsiher | : Frontiers Media SA |
Total Pages | : 180 |
Release | : 2021-11-12 |
Genre | : Science |
ISBN | : 9782889716289 |
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Practical Approach to Mammalian Cell and Organ Culture
Author | : Tapan Kumar Mukherjee,Parth Malik,Srirupa Mukherjee |
Publsiher | : Springer Nature |
Total Pages | : 1286 |
Release | : 2022-11-07 |
Genre | : Medical |
ISBN | : 9789811917318 |
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This Major Reference Work offers a detailed overview of culturing primary, secondary cell lines, tissues, and organs. It first introduces various types of mammalian cell cultures, infrastructure requirements for a mammalian cell-culture laboratory. The subsequent chapters present the detailed protocols for the isolation of mammalian hematologic organs and cells. It also discusses various cell-based assays for monitoring cell viability, cell proliferation, cytotoxicity, cell senescence, and cell death assays. In addition, the book addresses the various problems encountered while culturing animal cells, their possible causes, and suggested solutions, presenting detailed protocols for isolation and primary culturing of various mammalian cells and hematoimmunologic organs in two dimensions. Lastly, it reviews the various applications of animal-cell culture, stem-cell culture, and tissue and organ culture. As such, this reference book is highly relevant for students and professionals new to cell-culture work as well as to those wishing to expand their skills from cell-line cultures to primary cultures and from conventional 2D cultures to 3D cultures.
Advanced Imaging in Biology and Medicine
Author | : Ch.W. Sensen,Benedikt Hallgrimsson |
Publsiher | : Springer Science & Business Media |
Total Pages | : 447 |
Release | : 2008-12-03 |
Genre | : Medical |
ISBN | : 9783540689935 |
Download Advanced Imaging in Biology and Medicine Book in PDF, Epub and Kindle
A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed solely by imaging, and most of the surgical planning relies on the patient imagery. 4D ultrasound is available to expecting parents who wish to create unique early memories of the new baby, and it may soon be used for the morphometric diagnosis of malformations that may one day be treatable—inutero! Light and electron microscopy are unequal brethren, which have contributed to most of our knowledge about the existence and organization of cells, tissues and microorganisms. Every student of biology or medicine is introduced to the fascinating images of the microcosm. New advances have converted these im- ing technologies, which were considered by many to be antiquated, into powerful tools for research in systems biology and related ?elds.
Point Particles to Capture Polarized Embryonic Cells Cold Pools in the Atmosphere
Author | : Silas Boye Nissen |
Publsiher | : Niels Bohr Institute, Faculty of Science, University of Copenhagen |
Total Pages | : 319 |
Release | : 2020-08-31 |
Genre | : Science |
ISBN | : 9182736450XXX |
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Part 1: How are the incredible diversity and robustness compatible with animal morphologies? Based on apical-basal and planar cell polarities’ ubiquity, I suggest a 3D mathematical model: Point particles represent cells having zero, one, or two unit-arrows representing polarities. I test the model abilities on preimplantation development, sea urchin gastrulation, mammalian neurulation, organoid folding, and tubulogenesis. I find that a minimal, versatile toolbox, including cellular polarities, captures the emergence of diverse and robust animal morphologies. Part 2: How are deep convective events spatially organized in the tropical atmosphere? Here, I test the importance of atmospheric cold pools for organizing convection. I suggest a 2D mathematical model: Points expand into circles representing cold pools. When circles meet, a convective event occurs, and a new circle forms. I find this model captures convective scale increase and initial stages of convective self-aggregation. The latter is crucial due to its link to tropical cyclogenesis.