A Practical Manual For Musculoskeletal Research

This manual provides technical protocols for musculoskeletal research on a translational basis, i.e. a disease-orientated approach. It offers guidance on various laboratory techniques, including cell culture and molecular biology, histology and histomorphometry, microscopy and bioimaging, laboratory animal models, CT- and MRI-based densitometry and microarchitectural analysis, biomechanics and functional analysis of orthopedic kinesiology, etc. The content is simple and straightforward, with illustrations and step-by-step procedures as an easy experimental reference for personnel in basic and clinical musculoskeletal research and education. This book will provide a unique multidisciplinary platform for various professions OCo not only orthopedics, but also biomedical engineering and biomaterial sciences OCo involving both basic and clinical medicine."

Strong roots in basic science and research enhance clinical practice. This book is a rich source of information for basic scientists and translational researchers who focus on musculoskeletal tissues and for orthopedic and trauma surgeons seeking relevant up-to-date information on molecular biology and the mechanics of musculoskeletal tissue repair and regeneration. The book opens by discussing biomaterials and biomechanics, with detailed attention to the biologic response to implants and biomaterials and to the surface modification of implants, an important emerging research field. Finite element analysis, mechanical testing standards and gait analysis are covered. All these chapters are strongly connected to clinical applications. After a section on imaging techniques, musculoskeletal tissues and their functions are addressed, the coverage including, for example, stem cells, molecules important for growth and repair, regeneration of cartilage, tendons, ligaments, and peripheral nerves, and the genetic basis of orthopedic diseases. State-of-the-art applications such as platellet rich plasma were included. Imaging is a daily practice of scientists and medical doctors. Recent advancements in ultrasonography, computerized tomography, magnetic resonance, bone mineral density measurements using dual energy X-ray absorptiometry, and scintigraphy was covered following conventional radiography basics. Further extensive sections are devoted to pathology, oncogenesis and tumors, and pharmacology. Structure is always related with function. Surgical anatomy was therefore covered extensively in the last section.

An evidence-based reference for integrating manual medicine into everyday clinical practice Written by the authors of the popular Manual Medicine: Diagnostics and Manual Medicine: Therapy, this book is a comprehensive guide to integrating manual medicine into the diagnosis and clinical management of musculoskeletal disorders and pain syndromes. Brimming with instructive images and illustrations, the book provides a solid foundation in general principles of manual medicine, spinal biomechanics, neurophysiology, as well as treatments for each disorder and condition. Separate sections on the spine, limbs, and muscles present clinical applications for structural diagnosis and functional treatment. Highlights: Practical examples of evidence-based approaches to manual medicine 1,313 illustrations and photographs of superb quality that rapidly demonstrate key concepts Coverage of the essentials of the neuro-musculoskeletal examination with step-by-step descriptions of the techniques for observation, palpation, motion tests, functional examination, and provocative tests, including quick screening tests Chapter on the various components of nonradicular pain syndromes, including muscle pain syndromes, with clear diagnostic criteria for distinguishing the non-radicular and soft-tissue pain syndromes from other pain syndromes Succinct descriptions of common clinical neuro-orthopedic disorders and syndromes of the spine, upper limb, and lower limb in tabular format - ideal for rapid reference and review Discussion of the rationale for selecting particular low-risk treatment interventions, as well as a thorough discussion of indications and contraindications for patients with potentially increased risk Discussion of important considerations for documentation, informed consent, patient monitoring, and follow-up measures Practical section with descriptions of exercises for patients to do on their own Potential considerations for future research This book will serve as the definitive reference for all practitioners involved in the diagnosis and medical management of locomotor disorders and painful conditions. It will enable clinicians to enhance their diagnostic and treatment armamentarium by incorporating manual medicine techniques based on the current, evidence-based knowledge of the interrelationships between structure and function.

Written by the authors of the popular Manual Medicine: Diagnostics and Manual Medicine: Therapy, this book is a comprehensive guide to integrating manual medicine into the diagnosis and clinical management of musculoskeletal disorders and pain syndromes. Brimming with instructive images and illustrations, the book provides a solid foundation in general principles of manual medicine, spinal biomechanics, neurophysiology, as well as treatments for each disorder and condition. Separate sections on the spine, limbs, and muscles present clinical applications for structural diagnosis and functional treatment. Highlights: Practical examples of evidence-based approaches to manual medicine 1,313 illustrations and photographs of superb quality that rapidly demonstrate key concepts Coverage of the essentials of the neuro-musculoskeletal examination with step-by-step descriptions of the techniques for observation, palpation, motion tests, functional examination, and provocative tests, including quick screening tests Chapter on the various components of nonradicular pain syndromes, including muscle pain syndromes, with clear diagnostic criteria for distinguishing the non-radicular and soft-tissue pain syndromes from other pain syndromes Succinct descriptions of common clinical neuro-orthopedic disorders and syndromes of the spine, upper limb, and lower limb in tabular format - ideal for rapid reference and review Discussion of the rationale for selecting particular low-risk treatment interventions, as well as a thorough discussion of indications and contraindications for patients with potentially increased risk Discussion of important considerations for documentation, informed consent, patient monitoring, and follow-up measures Practical section with descriptions of exercises for patients to do on their own Potential considerations for future research This book will serve as the definitive reference for all practitioners involved in the diagnosis and medical management of locomotor disorders and painful conditions. It will enable clinicians to enhance their diagnostic and treatment armamentarium by incorporating manual medicine techniques based on the current, evidence-based knowledge of the interrelationships between structure and function.

This high-yield, user-friendly manual is a practical road map for all physicians who diagnose and treat patients with musculoskeletal symptoms, including physiatrists, orthopedists, internists, family practitioners, rheumatologists, and neurologists. Organized by anatomic region, the book provides a step-by-step approach to the diagnosis and aggressive nonsurgical management of common musculoskeletal symptoms. Each chapter opens with diagnosis and treatment algorithms for common chief complaints. Numerous high-yield points give a clear picture of each complaint and a logical, stepwise approach to management. The authors also indicate when a symptom is an emergency or requires surgical evaluation.