Active Phytochemicals From Chinese Herbal Medicines

Biomedical Science Chinese herbal medicine represents complementary or adjunctive therapies that often can improve the efficacy of Western medicine to achieve the pharmacological effects, especially in cancer treatment. However, the combination of herbs with therapeutic drugs can raise potential health risk. Building a bridge between Western medicine and herbal medicines, Active Phytochemicals from Chinese Herbal Medicines: Anti-Cancer Activities and Mechanisms gives you useful information on how integrated medicines can work for cancer therapy. It discusses the therapeutic uses of phytochemicals, adverse effects, and interactions with (Western) cancer drugs. The author takes a unique approach to integrated pharmacology of herbal medicines, examining the development of phytochemicals and their mechanisms of action in the context of the cancers and diseases they are used to treat. He covers biologic action of the active phytochemicals at the molecular, cellular, and organ levels. The book covers the principles of the interaction of phytochemicals and the related drug actions. It also addresses the common pathways affecting cancer development before discussing the phytochemical classes and specific phytochemicals that have been recently reported in journal papers for the management of cancer and other diseases. Highlighting the increasingly important aspects of pharmacology, including health benefit and drawbacks of phytochemicals, the book presents the relevant background of the biochemistry of the cancer. It includes illustrations and tables with adverse reactions that highlight important issues related to phytochemical actions. These features and more make the book a useful reference on phytochemicals obtained from herbal medicines. It blends coverage of fundamental mechanisms of anti-cancer action and the use of phytochemicals to manage cancers and other human diseases, allowing you to explore how herbal medicines can enhance conventional protocols.

This title was first published in 2003. In laboratories around the world the active principles in traditional herbal medicines are being isolated and characterized. A systematic effort at the Chinese Academy of Sciences is underway to identify the structure-activity relationships that result from the link between chemistry and medicine that is permitted by this data. This book, which provides the only systematic English-language description of the chemical structures and pharmacological effects of compounds active in traditional Chinese medicines (TCMs), is now in its second edition. The new edition provides English-language monographs on over 9000 chemicals isolated from nearly 4000 natural sources used in Chinese medicine and features the addition of in-depth bioactivity data for many of the compounds. Effects and indications of the medicines are included. Extensive indexing permits cross-referencing among English, Chinese and Latin names for natural medicinal sources, effects and indications, and the chemical components of the medicines. The second edition of Traditional Chinese Medicines includes 2300 new compounds, 2400 additional plant sources, more CAS Registry Numbers, and more pharmacological data. The structure of the book has been extensively reorganised to make cross referencing the data much simpler. This new edition is therefore a substantial improvement on the first edition of this important reference on the structural chemistry of traditional Chinese medicines.

Western drugs and target medicines for disease treatment come with undesirable side effects that have limited their use in patients for an extended period of time. It is warranted to develop a treatment strategy with alternative medicines to reduce toxicity relating to drugs, in particular, cancer drugs. Thus, a combination therapy with herbal medicines provides a more effective treatment method for hard-to-treat diseases. The recent breakthroughs in naturally occurring small molecules from herbal medicines have provided experimental evidence and are clinically significant in treatment strategies.This unique volume presents the recent developments in the field of herbal medicines for the treatment of diseases and cancer. Recent progress on small molecules isolated from herbal medicines that exhibit therapeutic benefits in humans is highlighted. The book provides an overview of the significant discoveries and pioneering contributions of herbal medicines in combination with other drugs; the author's evaluation of the combination therapy in cancer treatment; and a recent discovery of crocodile tissue extract with pharmacological properties.

Natural products are the most successful source of drugs. Of the 877 small-molecule new chemical entities introduced between 1981 and 2002, roughly half were natural products, semi-synthetic natural product analogues or natural mimics. Chinese herbs (traditional Chinese medicines, TCMs) have been used for prevention and treatment of diseases for thousands years. It has been attracting intensive attention in the trends of back to nature. As herbal medicines, the conditions of growth, harvest time, process and storage etc. will undoubtedly affect the presence and concentration of the bioactive constituents, thus affecting their quality and efficacy. Up to date, there are few books focussing on the relationship, which is the bridge between TCM and modern medical science, of traditional clinic uses, pharmacological activities and quality control of Chinese herbs. Unfortunately, bioactive compounds in Chinese herbs are usually not or only partially known. Actually, the active compounds considered in Chinese herbs may be different according to their clinical indication. In addition, it is considered that the curative effect of Chinese herbs is an integrative result of a number of bioactive compounds. Therefore, how to control the quality is a big problem. We would like to discuss the quality control based on their traditional clinical uses and pharmacological activities in this book, which is the fundamental step towards developing and modernising such products into evidence based medicines. It will also help the peoples to understand TCMs in modern scientific angles. This book is designed primarily as a textbook for or adjunct to course in herbal remedies, food safety or quality control of herbs. It is also a professional reference whom is in the area of drug discovery, pharmaceutical analysis and food chemistry.

The Second Edition of this book is a rearranged and enriched version of the previous edition, composed of feedback and constructive comments from readers. Acupuncture is the most popular form of treatment in Chinese medicine. The theories and practice of acupuncture have been revised and rewritten to give readers a clear idea of how it works and when it is to be utilized. Botanicals, i.e. herbal medicine, form the major core of Chinese medicine practice. The potential of botanicals development is wide: from casting specific biological activities to preventive uses. Three new chapters are offered: (i) for the understanding of the biological activities of herbal medicine, (ii) the products produced from herbs for specific needs, and (iii) the individual's choice for what may suit him/her best. In this present era of information technology, readers should be guided on the use of the Internet and related areas in order to independently secure information for personal use and research needs. The last chapter is provided for this practical purpose.Since the publication of the First Edition, much development has occurred in the field of Chinese medicine. All the chapters have been updated and revised accordingly so that general readers, those looking for effective treatment, as well as those who want to serve their patients better, can have a reliable comprehensive reference.

During the recent years, traditional Chinese medicine (TCM) has attracted the attention of researchers all over the world. It is looked upon not only as a bright pearl, but also a treasure house of ancient Chinese culture. Nowadays, TCM has become a subject area with high potential and the possibility for original innovation. This book titled Recent Advances in Theories and Practice of Chinese Medicine provides an authoritative and cutting-edge insight into TCM research, including its basic theories, diagnostic approach, current clinical applications, latest advances, and more. It discusses many often neglected important issues, such as the theory of TCM property, and how to carry out TCM research in the direction of TCM property theory using modern scientific technology. The authors of this book comprise an international group of recognized researchers who possess abundant clinical knowledge and research background due to their years of practicing TCM. Hopefully, this book will help our readers gain a deeper understanding of the unique characteristics of Chinese medicine.

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

This book is the first volume of a comprehensive 2-volume book covering modern pharmacological and clinical studies of the most commonly used Chinese herbal drugs. It contains monographs of 250 kinds of the most commonly used Chinese Materia Medica. The information on each herb was compiled by a research specialist active in the scientific investigation of that particular type of herb. The description on each drug includes an introduction (source, character and taste, actions and indications according to traditional Chinese medicine etc.), chemical composition, pharmacology, clinical studies, adverse effects and references. The translation of the book into English was done by qualified professionals in the field and the terms used are consistent with those used in Index Medicus, Chemical Abstracts and Botanical journals.