Advanced Nanoformulations

Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. Contains in-depth discussions of the advanced formulations using nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding Reviews the literature on advanced formulations while also suggesting new avenues Includes contributions in all areas of advanced formulations, providing a thorough and interdisciplinary work

In this first comprehensive compilation of review chapters on this hot topic, more than 30 experts from around the world provide in-depth chapters on their specific areas of expertise, covering such essential topics as: * Block Copolymer Systems, Nanofibers and Nanotubes * Helical Polymer-Based Supramolecular Films * Synthesis of Inorganic Nanotubes * Gold Nanoparticles and Carbon Nanotubes * Recent Advances in Metal Nanoparticle-Attached Electrodes * Oxidation Catalysis by Nanoscale Gold, Silver, and Copper * Concepts in Self-Assembly * Nanocomposites * Amphiphilic Poly(Oxyalkylene)-Amines * Mesoporous Alumina * Nanoceramics for Medical Applications * Ecological Toxicology of Engineered Carbon Nanoparticles * Molecular Imprinting * Near-Field Raman Imaging of Nanostructures and Devices * Fullerene-Rich Nanostructures * Interactions of Carbon Nanotubes with Biomolecules * Nanoparticle-Cored Dendrimers and Hyperbranched Polymers * Nanostructured Organogels via Molecular Self-Assembly * Structural DNA Nanotechnology With its coverage of all such important areas as self-assembly, polymeric materials, bionanomaterials, nanotubes, photonic and environmental aspects, this is an essential reference for materials scientists, engineers, chemists, physicists and biologists wishing to gain an in-depth knowledge of all the disciplines involved.

Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful. Brings together the novel applications of nanotechnology in biological fields Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications

This is the first major compilation of new advances covering the current status and topics related to the processing and production of precisely controlled materials. It provides a unique source of information and guidance for specialists and non-specialists alike. This book represents an extended introductory treatise on the fundamental aspects, new methods for the precise control of morphology (size, shape, composition, structure etc.) and accurate materials characterization, from both the basic science and the applied engineering viewpoints.

This textbook provides an overview of applications of advanced nanomaterials, basic lab set up and requirements in for their synthesis, techniques and career scope of nanotechnology in industries and research. Pollution of air, water, soil is an ever increasing environmental problem attributed to increasing population, global industrialization and unplanned urbanization, has acquired alarming dimensions. It is the most dangerous and worst problem that puts the lives of people, animals, and plants on the earth in danger. An effective, efficient and sustainable approach for managing pollution related problems requires the utmost attention of the scientific community to tackle this menace for the society to lead a healthy and quality life. A number of techniques and books, literatures have been developed in recent years to treat environmental contaminants. However, most of these are not economically viable, environmentally benign and suffer due to cumbersome multi-step manipulations. The purpose of this textbook is to inform students about the application of functionalized nanoparticles as a new approach to supplement traditional treatment methods in cost and time effective manner. The simplistic means to assemble nanoparticles to the constituents of next generation technologies in environment cleanup and sensing are the main objectives of the book. The toxicological footprinting of released advanced functional nanomaterials in ecosystem will also be discussed in the book.

A collection of highly selected, peer-reviewed chapters, this book showcases the research of an international roster of scientists. It covers nanomaterials with emphasis on synthesis, characterization, and applications. It also presents emerging developments in nanotechnology in areas as diverse as medicine, energy, electronics, and agriculture. In addition to engineering aspects, the book discusses the physics, chemistry and biotechnology behind the fabrication and device designing.