Advances In Wound Healing Materials

Wound healing and wound care technologies are an ever expanding field with the advancement of materials science, biomedicine and tissue engineering. In the year 2011 the global wound care market generated US$ 6,500 million with an annual growth rate of 7.5%. The global advanced wound care products market share in 2023 is predicted to be approximately US$ 16,300 million.This book discusses the evolution of wound care devices and protocol over the years and different technologies being used in the present day wound care treatment. New strategies involving engineered tissues and drug delivery to mimic the natural wound healing milieu are discussed. The use of cytokine growth factors enhances chronic wound healing particularly for burn wound healing. Prevention of scarring, keloid formation or contractures and a cosmetically acceptable healing is a challenge even now.Skin tissue engineering was the first successfully clinically applied product in regenerative medicine. Bioengineered skin seeded with fibroblast and keratinocyte cells could form a permanent solution that do not require skin grafting or as a temporary cover for burns prior to grafting. Cell attachment, proliferation and tissue formation in a three-dimensional porous scaffold can be engineered for specific application. These cell based skin substitutes had significant wound healing and scar reducing effect on patients.Gene-activated dermal equivalent is another emerging approach for the healing of full thickness incision wounds with good remodelling of the skin. The book also describes similar latest developments on wound healing science and research.The target audiences are wound care professionals, researchers working on wound healing technology and skin tissue engineering; as well as graduate students and industries that need to understand the aspects of wound healing and technological orientation towards successful commercialisation.

Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds. Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices. With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair

Advanced Textiles for Wound Care, Second Edition, provides a detailed review of how textiles are incorporated into wound care applications, also explaining the importance and suitability of using textiles on different wound types. It is an interdisciplinary book which directly links textile technology with advances in wound care. The book discusses new developments and techniques related to antimicrobial dressings, the use of biopolymers in infection control management, advanced dressings for managing cavity and cancerous wounds, and the application of nanofibers and novel textile structures in scaffolds, among other new areas. This updated edition also reflects recent changes in regulatory affairs. The book is essential reading for manufacturers, designers, scientists and producers of wound care materials. It is a valuable resource for professionals within the medical sector, as well as those in academia, enabling materials scientists and engineers in both academia, and at medical device companies, to stay abreast of new technology. Provides a comprehensive introduction to wound care, from the different types of wound and wound healing mechanisms, to the importance of testing in relation to wound care Analyzes the application of textiles to wound healing, covering minor wounds, burns, ulcers and other deep skin wounds Reviews the current use of smart textiles for wound care, including drug delivery dressings and textile-based scaffolds for tissue engineering

Innovations and Emerging Technologies in Wound Care is a pivotal book on the prevention and management of chronic and non-healing wounds. The book clearly presents the research and evidence that should be considered when planning care interventions to improve health related outcomes for patients. New and emerging technologies are discussed and identified, along with tactics on how they can be integrated into clinical practice. This book offers readers a bridge between biomedical engineering and medicine, with an emphasis on technological innovations. It includes contributions from engineers, scientists, clinicians and industry professionals. Users will find this resource to be a complete picture of the latest knowledge on the tolerance of human tissues to sustained mechanical and thermal loads that also provides a deeper understanding of the risk for onset and development of chronic wounds. Describes the state-of-knowledge in wound research, including tissue damage cascades and healing processes Covers all state-of-the-art technology in wound prevention, diagnosis, prognosis and treatment Discusses emerging research directions and future technology trends in the field of wound prevention and care Offers a bench-to-bedside exploration of the key issues that affect the practice of prevention and management of non-healing wounds

The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.

This book outlines, from a surgeon’s standpoint, how physicians and mid-level providers working at wound care centres can expeditiously and effectively manage wounds. It comprehensively addresses the concept of wound healing, from the healing process to debridement concepts, and various antiseptics and local antibiotics used in dressing materials to facilitate healing. The book also discusses the latest inventions and treatment options that have revolutionized wound healing, such as: oxygen therapy, ozone therapy, hyperbaric oxygen therapy, electric therapy and ultrasonic wound therapy. In closing, it examines the latest regenerative therapies based on stem cell therapy, cellular therapy and gene therapy. Given its scope, the book offers a valuable resource for medical students and physicians dealing with wound management, as well as a reference guide for nurses in primary and tertiary wound care settings.

Dressings for Advanced Wound Care focuses on helping the reader better understand advanced wound care and relevant technologies. It explains how different types of wounds may require different environments to heal and how dressings can help in creating the right environment. It gives an overview of the various dressing technologies that are available to help manage wounds that are difficult to heal. Finally, this book highlights the current trends that may be directing the future of the advanced wound dressing sector. FEATURES: Relates technologies with commercially available end-products, giving the reader a more specific overview of the advanced wound dressing sector Provides a realistic overview of the process of developing an advanced wound care dressing Summarises recent clinical evidence on advanced wound dressings Explains how dressings differ and what works best for which wound type Examines clinical evidence on technologies and on-market products Describes the requirements for launching a new advanced wound dressing This book is aimed at medical clinicians and professionals in the fields of biomedical engineering, textile science, and materials engineering.

This book presents state of the art knowledge on new techniques and materials that can improve functional and aesthetic results in wound healing while reducing invasiveness, based on the author's extensive personal experience. The aim is to equip the practitioner with all the information required in order to select a strategy that will accelerate wound healing and minimize both the risk of complications and scar formation after the wound has fully healed. The opening chapters set the stage by providing an overview of wound healing, including brief descriptions of the anatomy of the skin, the wound healing process, and advanced wound dressings. A full description follows of the various methodologies employed in repairing acute wounds with the goal of achieving optimal functional and cosmetic outcomes while utilizing the safest and least invasive method. Treatment protocols that have proven successful in closing nonhealing and/or delayed healing chronic wounds are then presented. In addition, a chapter addresses aesthetic procedures using advanced technology in wound healing. The closing chapter presents author’s experience with the establishment a hospital wound dressing team. The text is supported by 1,411 full color photos. Since the publication of the second edition, there have been many notable advances in wound healing research. The third edition is expanded and updated to reflect the advancements and new information. Key revisions include new chapters and/or sections on recently developed dressings such as a bioelectric dressing, a fluorescence imaging device of bacteria, usefulness of fibrin glue to support wound healing, graft of 3D-printed micronized adipose tissue, significance of skin hydration level for wound healing, novel staged excision technique to reduce scar length, newly developed risk scoring system to predict wound healing outcomes in diabetic patients, expanded coverage of cell therapy, new devices such as extracorporeal shock wave therapy, and automated SVF cell isolation system.