Alzheimer Disease

Nearly 44 million people have Alzheimer’s or related dementia worldwide, according to the Alzheimer’s Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer’s and other forms of dementia. First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer’s disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer’s disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer’s diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer’s disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer’s disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients. Reviews recent developments of cognitive and clinical studies Covers factors underlying the transition from mild cognitive impairment to Alzheimer’s disease Discusses different neural biomarkers underlying the development and treatment of Alzheimer’s disease Provides a comparison of the effectiveness of various types of treatments

Nearly 44 million people have Alzheimer's or a related dementia worldwide, according to the Alzheimer's Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Recent Advancement in Alzheimer's Disease Research: Neural and Cognitive Studies aims to cover all recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer's and other forms of dementia. First, readers are introduced to the cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to symptoms and the quality of life in Alzheimer's disease. In addition, the author discusses recent studies on memory dysfunction in advanced-stage Alzheimer's disease, in comparison to early-stage Alzheimer's disease; including a chapter on the factors underlying transition from mild cognitive impairment to Alzheimer's disease. Following this section, the author presents recent studies on the role of different cortical and subcortical structures in the development of different symptoms in Alzheimer's disease as well as different neural biomarkers underlying the development and treatment of Alzheimer's disease. In the last section of the book, therapeutic aspects of Alzheimer's disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, in Alzheimer's disease are reviewed. Recent Advancement in Alzheimer's Disease Research: Neural and Cognitive Studies aid readers with keeping up with the advances in research and care making it making it a prime tool for all clinicians, psychologists, researcher, neurologists, and caregivers of patients. Reviews recent developments of cognitive and clinical studies Covers factors underlying transition from mild cognitive impairment to Alzheimer's disease Discusses different neural biomarkers underlying the development and treatment of Alzheimer's disease Provides a comparison on the effectiveness of various types of treatments

This book provides a practically focused resource on the methodologies available for diagnosing and treating Alzheimer’s disease. The number of individuals affected by the disease continues to grow and as such there is an ever-increasing need for clear easy-to-digest guidance on how to appropriately diagnose and treat these patients. Within this work, chapters provide concise informative details of what this form of dementia is, how it can be diagnosed, managed and prevented making it ideal for those with limited experience in dealing with these patients. Information is provided on how to use a variety of the latest relevant techniques including mental state examinations, functional assessments, special investigations and the available drug treatments. Alzheimer’s Disease: Diagnosis & Treatment Guide is a concise clinical guide detailing how to diagnose and treat these patients. It’s easy-to-follow ideal for use by front-line physicians and trainees, who have no previous experience of diagnosing and treating this disease. The assessment component of the book is based on the WHO Mental Health Gap Action Plan (mhGAP) Dementia Intervention Guide for non-specialized settings.

Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest

As the essays in this volume show, conceptualizing dementia has always been a complex process. With contributions from noted professionals in psychiatry, neurology, molecular biology, sociology, history, ethics, and health policy, Concepts of Alzheimer Disease looks at the ways in which Alzheimer disease has been defined in various historical and cultural contexts. The book covers every major development in the field, from the first case described by Alois Alzheimer in 1907 through groundbreaking work on the genetics of the disease. Essays examine not only the prominent role that biomedical and clinical researchers have played in defining Alzheimer disease, but also the ways in which the perspectives of patients, their caregivers, and the broader public have shaped concepts.

The guide tells you how to: Understand how AD changes a person Learn how to cope with these changes Help family and friends understand AD Plan for the future Make your home safe for the person with AD Manage everyday activities like eating, bathing, dressing, and grooming Take care of yourself Get help with caregiving Find out about helpful resources, such as websites, support groups, government agencies, and adult day care programs Choose a full-time care facility for the person with AD if needed Learn about common behavior and medical problems of people with AD and some medicines that may help Cope with late-stage AD

Now presented in full color, this updated edition of Memory Loss, Alzheimer's Disease, and Dementia is designed as a practical guide for clinicians that delivers the latest treatment approaches and research findings for dementia and related illnesses. Drs. Budson and Solomon — both key leaders in the field — cover the essentials of physical and cognitive examinations and laboratory and imaging studies, giving you the tools you need to consistently make accurate diagnoses in this rapidly growing area. Access in-depth coverage of clinically useful diagnostic tests and the latest treatment approaches. Detailed case studies facilitate the management of both common and uncommon conditions. Comprehensive coverage of hot topics such as chronic traumatic encephalopathy, in addition to new criteria on vascular dementia and vascular cognitive impairment. Includes new National Institute on Aging–Alzheimer's Association and DSM-5 criteria for Alzheimer’s Disease and Mild Cognitive Impairment. Learn how to use new diagnostic tests, such as the amyloid imaging scans florbetapir (Amyvid), flutemetamol (Vizamyl), and florbetaben (Neuraceq), which can display amyloid plaques in the living brains of patients. Updated case studies, many complete with videos illustrating common tests, clinical signs, and diagnostic features, are now incorporated into the main text as clinical vignettes for all major disorders. Brand-new chapters on how to approach the differential diagnosis and on primary progressive aphasia. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

In this second edition Dr. Newport, a neonatal practitioner, continues the story of Steve's progress and provides the most recent research on such topics as possible causes of Alzheimer's due to the herpes simplex virus and nitrosamine substances and how infection, inflammation and genetic makeup may affect an individual's response to fatty acid therapy.