Anaphylaxis

The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading.

A well-known scientist, who has recently discovered an effective vaccine for cocaine addiction, dies from anaphylaxis after a routine injection in the office of his allergist, Dr. Leonard Haberman. A malpractice lawsuit ensues, fanned by a politically ambitious senator. Questions arise when it is discovered that the cocaine vaccine specifications are missing along with the head technician who worked closely with the deceased scientist. CBI Agent Ben Locke connects these events with a cold case involving the mysterious death of another scientist and a nefarious plot implicating an organized mob is exposed, placing Haberman and his family at great risk.

Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients. Quick and easy reference for understanding problems in neuroanesthesia Provides comprehensive insights into all possible complications occurring during perioperative management of neurosurgical and neurologic patients Includes useful section with clinical case studies of complications in neuroanesthesia

This book serves as a comprehensive but concise, practical, in-depth resource for practitioners who see and treat anaphylaxis. It meets the market need for a reference that relays an advanced understanding of the condition and its management. This unique reference covers management beyond the basics, including discussions around prevention of biphasic anaphylaxis, optimal post-stabilization protocols and how to work up intraoperative anaphylaxis. Additionally, various chapters delve into the practical application of equipping one’s office for the management of anaphylaxis, specifically in the setting of a reaction to a food challenge or immunotherapy injection. Anaphylaxis: A Practical Guide is an essential resource for allergists, emergency room physicians, and pediatricians, and those in training to become members of these specialties.

Despite wide recognition as a serious public health problem, anaphylaxis and hypersensitivity reactions remain under-recognized and under-diagnosed. This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets. The book provides a detailed examination of disease etiology, pathogenesis, and pathophysiology and their correlation to clinical practice. Forefront knowledge of the mediators and mechanisms of anaphylaxis is covered with an emphasis on how new discoveries shape our current and emerging therapies.

Anaphylaxis is an immediate-type allergic reaction involving the whole organism. It is the most life-threatening allergic condition. Although there are few exact epidemiological data regarding prevalence, estimates regarding insect sting anaphylaxis range from 1-3% in the general population, but much higher values have been reported by some authors for food and drug-induced anaphylaxis. Anaphylaxis is the main acute killer of allergic individuals.Although anaphylaxis was discovered at the beginning of the 20th century, there are still many unresolved issues. These include non-IgE-mediated anap.

This new title is aimed at everyone whose life is affected by life-threatening allergic reactions. Easy to understand and full of vital information, this book explains how to identify the condition, how to recognise the early signs of an attack, etc.