Antidiabetic Medicinal Plants

This work presents a systematic review of traditional herbal medicine and their active compounds, as well as their mechanism of action in the prevention and treatment of diabetes and obesity. The side effects and safety of herbal-derived anti-diabetic and anti-obesity phytochemicals are detailed in depth, and the text has a strong focus on current and future trends in anti-diabetic medicinal plants. This unique and comprehensive text is the only current book on the market focusing exclusively on medicinal plants used to combat obesity and diabetes. An introductory chapter focuses on diabetes and obesity and introduces the major causes and main treatments of this increasing epidemic in modern society. Readers are then introduced to medicinal plants, including details on their therapeutic aspects, plus side effects and safety. Following chapters focus on anti-diabetic and anti-obesity medicinal plants, as well as phytogenic natural products in the treatment of each. The text closes by focusing on present and future trends and challenges in these medicinal plants. Anti-diabetes and Anti-obesity Medicinal Plants and Phytochemicals: Safety, Efficacy, and Action Mechanisms is a much-needed and truly original work, finally presenting in one place all the necessary information on medicinal plants used in conjunction with obesity and diabetes prevention.

The increasing prevalence of diabetes mellitus world-wide is an issue of major socio-economic concern. Scientific interest in plant-derived medicine is steadily rising, yet there is often a wide disparity in the caliber of information available. A detailed compilation of scientific information from across the globe, Traditional Medicines for Modern Times: Antidiabetic Plants highlights the potential role of dietary and medicinal plant materials in the prevention, treatment, and control of diabetes and its complications. The book not only describes plants traditionally used to treat diabetes, but evaluates the scientific studies on these plants and describes in vitro, in vivo, and clinical methods for their investigation. It examines the theory that changes in dietary patterns from traditional plant foodstuffs containing beneficial components, to richer, more processed "junk" food is responsible for the increased prevalence of diabetes worldwide. The book begins with an introduction to the disease diabetes mellitus written by a consultant physician and an up-to-date, detailed summary table and discussion of scientifically screened antidiabetic plants compiled by authors from the Jodrell Laboratories, Royal Botanic Gardens, Kew, UK. The next chapters provide an outline of clinical, in vivo, and in vitro methods for assessing antidiabetic activity of plant materials, followed by descriptions of traditional plant remedies used in Asia, the Americas, Africa, Europe, and Australia written by an international group of authors active in antidiabetic plant research. The final chapters emphasize the role of particular phytochemical groups in the treatment or prevention of diabetes. By documenting both traditional and scientifically derived knowledge, Traditional Medicines for Modern Times: Antidiabetic Plants brings us closer to the translation of traditional knowledge into new methods for treatment of this important disease.

This book is a unique overview of insights on the genetic basis of anti-diabetic activity, chemistry, physiology, biotechnology, mode-of-action, as well as cellular mechanisms of anti-diabetic secondary metabolites from medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. There is an increasing demand for medicinal plants having anti-diabetic potential in both developing and developed countries. The expanding trade in medicinal plants has serious implications on the survival of several plant species, with many under threat to become extinct. This book describes various approaches to conserve these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication, cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in the plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. The book is enriched with expert contributions from across the globe. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as diabetic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, Ayurveda, Siddha, Unani and other traditional medical practitioners.

Here is an informative overview of diabetes mellitus in conjunction with plant-based treatments. It discusses available methods for studying the antidiabetic activities of scientifically developed plant products, mechanisms of action, their therapeutic superiority, and current genome editing research perspectives and biotechnological approaches. The book begins with an introduction to diabetes, giving a brief overview of the history, diagnosis, classification, pathophysiology, and risk factors. It goes on to review traditional uses of plants for diabetes along with ethnobotanical information. The results of scientific studies on the various modes of action of antidiabetic plants are discussed, such as the molecular aspects of active plantbased antidiabetic drug molecules. A section featuring recent biotechnological advancements of antidiabetic plants and plant-based antidiabetic drugs covers advances in molecular breeding and application of molecular markers, biotechnologically engineered transgenic medicinal plants, and advances in genomic editing tools and techniques.

Medicinal Plants with Antidiabetic Properties: Applications and Opportunities is the first comprehensive reference to present the state of current research as well as those developments that are impacting developments in the use of plants to address diabetic conditions. Presenting multiple perspectives on the plants, their identification, cultivation and application, this book presents the state of the art with an eye toward the future. Herbal drugs and their components with insignificant toxicity and limited or no side effects are valuable therapeutic alternatives in the treatment of diabetes around the world and have been considered a fundamental source of potent antidiabetic drugs. Exploration of plants containing numerous bio-active compounds such as flavonoids, terpenoids, saponins, carotenoids, alkaloids, and glycosides, for their potential antidiabetic properties is increasing as alternative treatments for this globally devastating disease are sought. Presented in 5 parts, the book first provides an overview of those plants with antidiabetic properties, then moves to the agricultural practices for the cultivation and production of those plants. Part Three focuses on the chemical composition and phytochemicals of the plants before then moving into a study of the physiological, biotechnological and molecular approaches to optimizing these plants. The book concludes with insights into current and potential future medical and clinical applications. The book is ideal for those seeking to understand the biology and chemistry of plants with anti-diabetic properties and their effective development and application. Includes insights from laboratory research to field application Presents perspectives from agriculture, biotechnology, molecular biology, pharmaceutical, pharmacological, and clinical trials Highlights the cost-effective and eco-friendly technologies for the sustainable agriculture development of antidiabetic plants

"Diabetes is a chronic problem associated with the metabolic disorder. Persons suffering from diabetes have shown an accelerated levels of blood sugar, which often harms the heart, blood vessels, eyes, kidneys and nerves. Over the past few decades, the prevalence of diabetes has been progressively increasing. In this connection, synthetic drugs are used to treat the diabetic patients and keep the disorder under control. However, in the form of substitute numerous medicinal plants and herbal drugs are widely used in several traditional systems of medicine to prevent diabetes, and Several plant-based drugs are now available in the market. They have been reported to show multiple beneficial effects in combating diabetes and alleviating the diabetes-related complications. Numerous phytonutrients and or phytoconstituents have been identified and extracted from these plants. They have shown protective or disease preventive properties. In many developing countries, diabetes treatment with synthetic drugs looks to be an expensive process due to poverty and lack of free medical facility etc. Thus, herbal drugs are recommended by traditional practitioners for their therapeutic value and/or antidiabetic response. Taken together, the aim of the book is to provide an overview on the most important and selected antidiabetic plants and the natural products obtained from these plants. This book provide valuable information to scientists, researchers and students, working specially on medicinal plants, or in areas of ethnomedicine, natural products, economic botany, plant biochemistry, biotechnology, pharmacognosy, industrial chemistry, and other allied subjects. This book also help in testifying the various reports on antidiabetic plants and their other potential uses in new drug discovery based on their bioactive molecules, and also useful for pharmaceutical companies, industrialists and health policy makers"--

The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.