Antimicrobial Nanosystems

Antimicrobial Nanosystems: Fabrication and Development provides an in-depth review of nanotechnological advancements in the fields of biotechnology and pharmaceutical industries to counteract bacterial infections and related health issues. Functionalized nanomaterials and their processes are covered, along with the theory and fabrication of antimicrobial nanosystems. The potential applications of antimicrobial nanosystems are also discussed along with their challenges and commercialization. This book discusses the most frequent problems caused by resistant microorganisms and difficult-to-treat bacteria and highlights the impact of recently developed antimicrobial nanosystems. Various methodsto obtain efficient nanomaterials with antimicrobial properties are described, along with their advantages, challenges, and main applications. The design of targeting antimicrobial therapeutics, able to specifically detect pathogenic microorganisms and to act in a very specific manner, is thoroughly investigated. Discusses the most frequent problems caused by resistant microorganisms and difficult-to-treat bacteria Includes various methods to obtain efficient nanomaterials with antimicrobial properties that are described along with their advantages, challenges and main applications Covers the ability of microbes to adapt and select resistance, a major challenge in the design of alternative antimicrobial agents Provides various sections that illustrate the fabrication and development of antimicrobial nanosystems

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.

Antibiotics, the backbone of modern clinical-medicine, are facing serious challenges from emerging antimicrobial-resistance (AMR), a complicated phenomenon expanding in bacterial species, from nosocomial to community origins, where microbes are no longer sensitive to a range of commonly used antibiotics. AMR has exploded in recent years and is posing a serious threat to human health and survival. This necessitates novel and effective ways of diagnosis, drug-delivery, and treatment; nanotechnology and advanced nanomaterials are hailed as a potent solution in containing AMR.The main thrust of this volume is to explain the most current research on the central theme of potential use of nano-approaches for diagnosis, detection, drug-delivery and as antimicrobial agents against drug-resistant pathogenic microbes. This book provides an integrated blend of basic and advanced information for students, scholars, scientists and practitioners, interested or already engaged in research in these areas. We have brought together leading international authors to present and highlight various aspects of nanotechnology in combating AMR in WHO-prioritized microbes. Topics range from advances in nanomaterial synthesis, characterization, functionalization and improvisation, as well as applications in sensing, diagnosis of AMR, and their therapeutic and drug-delivery potential against MDR and XDR microbial phenotypes.

Nanotechnology can be used to address challenges faced by the food and bioprocessing industries for developing and implementing improved or novel systems that can produce safer, nutritious, healthier, sustainable, and environmental-friendly food products. This book overviews the most recent advances made on the field of nanoscience and nanotechnology that significantly influenced the food industry. Advances in Processing Technologies for Bio-Based Nanosystems in Food provides a multidisciplinary review of the complex mechanisms involved in the research, development, production and legislation of food containing nanostructures systems. Features: Presents the most recent advances made in the field of nanoscience and nanotechnology as applied to the food industry Discusses innovative approaches and processing technologies Shows how nanotechnology can be used to produce safer, nutritious, healthier, sustainable and environmental-friendly food products Covers the complex mechanisms involved in the research, development, production and legislation of food containing nanostructures Selected examples of nanotechnology applications in food industry are shown, focusing on advanced aspects of food packaging, processing and preservation; followed by one contribution that presents the potential commercialization and the main challenges for scale-up. Comprised of 15 chapters, this book provides much-needed and up-to-date information on the use of emergent technologies in bio-based nanosystems for foods, and serves as an ideal reference for scientists, regulators, industrialists, and consumers that conduct research and development in the food processing industry.

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

Polymeric Nanosystems: Theranostic Nanosystems, Volume One examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. Contains in-depth discussions of the polymeric nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding Reviews the literature on polymeric nanosystems while also suggesting new avenues Includes contributions in all areas of polymeric nanosystems, providing a thorough and interdisciplinary work