Applied Principles Of Biomaterials In Nanomedicine

This book is a collection of reviews and original researches by experts and scientists working in the field of biomaterials, its development and applications. It offers readers the potentials of distinct synthetic and engineered biomaterials. This book gives a comprehensive summary of the applications of various biomaterials, along with the techniques required for designing, developing and classifying these biomaterials without any intervention by any industrial source. Biomaterial structures and supramolecules are examined as protein carriers, tissue scaffolds etc. The researches and reviews focus on the functions of novel and familiar macromolecular compounds in nanotechnology and nanomedicine. The book also elucidates the chemical and mechanical modeling of these compounds so as to serve biomedical needs.

Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine. This book offers comprehensive knowledge of and diverse perspectives on nanomedicine through two independent volumes. It aims to bridge the gap between nanotechnology and medicine through contributions by world-renowned experts from wide range of backgrounds including academia, industry, professional consultancy, and government agencies. Each contribution integrates knowledge from a wide range of areas to present the fundamentals of new applications and products of nanomedicine, as well as an outlook for the future. This book can well serve as a reference and guide for students, academics, researchers, scientists, engineers, clinicians, government researchers, and healthcare professionals.

The scope of nanotechnology in medical applications has expanded fast in the last two decades. With their unprecedented material properties, nanoscale materials present with unorthodox opportunities in a wide range of domains, including drug delivery and medical imaging. This book assembles the various facets of nanomedicine while discussing key issues such as physicochemical properties that enhance the appeal of nanomedicine. The book is an excellent resource for physicians, PhDs, and postdocs involved in nanomedicine research to learn and understand the scope and complexity of the subject. It begins with a short history of nanotechnology, followed by a discussion on the fundamental concepts and extraordinary properties of nanoscale materials, and then slowly unfolds into multiple chapters illustrating the uses of various nanomaterials in drug delivery, sensing, and imaging.

Nanoengineered Biomaterials for Regenerative Medicine showcases the advances that have taken place in recent years as an increasing number of nanoengineered biomaterials have been targeted to various organ tissues. The book systematically explores how nanoengineered biomaterials are used in different aspects of regenerative medicine, including bone regeneration, brain tissue reconstruction and kidney repair. It is a valuable reference resource for scientists working in biomaterials science who want to learn more about how nanoengineered materials are practically applied in regenerative medicine. Nanoengineered biomaterials have gained particular focus due to their many advantages over conventional techniques for tissue repair. As a wide range of biomaterials and nanotechnology techniques have been examined for the regeneration of tissues, this book highlights the discussions and advancements made. Provides a digestible reference source for surgeons and physicians who want to learn more on nanoengineered biomaterials and their use in effective medical treatments Offers systematic coverage on how nanoengineered biomaterials are used for different types of medicine Assesses the benefits and drawbacks of the use of bioengineered nanomaterials in different areas of regenerative medicine

Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine Includes the translational or commercialization status of these new biomaterials Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials

Although nanotechnology applied to medicine has a potentially huge impact on drug delivery and tissue engineering, significant challenges need to be resolved before clinically viable nanomedicine or nanobiomedicine therapies will be available. Skillfully edited, with contributions from an expert panel of researchers, Nanotechnology in Tissue Engineering and Regenerative Medicine discusses the use of nanotechnology for medical applications with a focus on its use for drug delivery and tissue engineering. It sheds light on the challenges facing the field and examines cutting-edge research that may provide solutions. Topics covered include: Patterning of biomimetic substrates with AFM lithography, primarily focusing on DPN Nanotemplating polymer melts Nanotechnology-based approaches in the treatment of injuries to tendons and ligaments Progress in the use of electrospinning processing techniques for fabricating nanofiber scaffolds for neural applications Nanotopography techniques for tissue-engineered scaffolds and the effects of nanotopography on cells and tissues Vertically aligned TiO2 nanotube surface structuring for optimization of Ti implants utilizing nanotechnology Applications originating from the harmony of nanotechnology to biological systems, especially for the regeneration in the nervous system Current understanding of the mechanisms by which cells sense nano-scale structure at the molecular level and how this understanding can be useful in developing novel antifouling materials While there are books available on tissue engineering and nanotechnology and others about regenerative medicine, most do not comprehensively cover applications of nanotechnology to both these areas. Focusing chiefly on drug delivery, tissue engineering, and regenerative medicine, the book uses an application-based approach to relate laboratory-based research to the development of technologies that can be readily adaptable to an industrial environment.

The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.

This book fills the gap between fundamental and applied research in the use of nanomaterials in biomedical applications, covering the most relevant areas, such as the fundamental concepts of the preparation of nanostructures and regulatory requirements for their safe use in biomedical devices. It also critically discusses what has been achieved in the field, and what needs to be urgently addressed and reviews the state-of-the-art medical uses of nanomaterials for treating damaged organs and tissues. Combining the expertise of clinical researchers working in the field of tissue engineering and novel materials, the book explores the main topics regarding the characterization of materials, specific organ-oriented biomaterials and their applications, as well as regulations and safety. Further, it also examines recent advances, difficulties, and clinical requirements in terms of human bone, cornea, heart, skin and the nervous system, allowing readers to gain a clear and comprehensive understanding of current nanomaterial use in biomedical applications and devices, together with the challenges and future trends. This book is a valuable tool for multidisciplinary scientists and experts interested in fundamental concepts and synthetic routes for preparing nanomaterials. It is also of interest to students and researchers involved in cross-disciplinary research in nanomaterials for clinical applications and offers practical insights for clinicians as well as engineers and materials scientists working in nanoengineering.