Aqueous Microwave Assisted Chemistry

The demands for green and sustainable synthetic methods in the fields of healthcare and fine chemicals, combined with the pressure to produce these substances expeditiously and in an environmentally benign fashion, pose significant challenges to the synthetic chemical community. Green chemistry can avoid pollution by utilizing techniques that are environmentally friendly by design and one of the best green techniques is the use of microwave (MW) assisted aqueous synthetic protocols. Fusing MW technique with water (as a benign reaction medium) can offer an extraordinary synergistic effect with greater potential than these two individual components in isolation. Selective microwave heating can be exploited to develop a high yield protocol and the use of water expedites the MW-protocol with more energy efficiency. This book provides an overview of the various processes developed using aqueous microwave chemistry and is written for chemists, chemical engineers and researchers in the early stages who want to develop sustainable and green processes. Written by well known microwave experts, the book is a comprehensive examination of the field and is the first book that deals strictly with aqueous microwave chemistry and represents a significant effort towards green chemistry. It covers all the microwave-assisted aqueous reactions in depth, including heterocycle synthesis, metal catalysis, enzyme catalysis, polymer synthesis, nanomaterials synthesis and nano-catalysis. Each chapter contains representative experimental procedures, helping the reader quickly replicate some of the experiments to gain hands-on experience.

The demands for green and sustainable synthetic methods in the fields of healthcare and fine chemicals, combined with the pressure to produce these substances expeditiously and in an environmentally benign fashion, pose significant challenges to the synthetic chemical community. Green chemistry can avoid pollution by utilizing techniques that are environmentally friendly by design and one of the best green techniques is the use of microwave (MW) assisted aqueous synthetic protocols. Fusing MW technique with water (as a benign reaction medium) can offer an extraordinary synergistic effect with greater potential than these two individual components in isolation. Selective microwave heating can be exploited to develop a high yield protocol and the use of water expedites the MW-protocol with more energy efficiency. This book provides an overview of the various processes developed using aqueous microwave chemistry and is written for chemists, chemical engineers and researchers in the early stages who want to develop sustainable and green processes. Written by well known microwave experts, the book is a comprehensive examination of the field and is the first book that deals strictly with aqueous microwave chemistry and represents a significant effort towards green chemistry. It covers all the microwave-assisted aqueous reactions in depth, including heterocycle synthesis, metal catalysis, enzyme catalysis, polymer synthesis, nanomaterials synthesis and nano-catalysis. Each chapter contains representative experimental procedures, helping the reader quickly replicate some of the experiments to gain hands-on experience.

Advances in Microwave Chemistry discusses the novel bond formation methodologies, synergistic effects of microwaves with other entities, sample preparation including digestion, combustion, and extraction techniques, as well as selectivity in chemical processes. Recent updates are provided on microwave-assisted syntheses of pharmacologically significant aza-, oxo- and other heterocycles, including lactams, nucleosides, bile acids and sterols, the preparation of nanomaterials, composites, and absorber layer materials for thin film. This book also incorporates comparative discussions involving microwave irradiation with conventional methods in different aspects of organic, inorganic, medicinal, and green chemistry. Key Features: Provides a comparative discussion on microwave irradiation with conventional methods in different aspects of organic, inorganic, medicinal, and green chemistry Presents recent applications of microwave radiation in biocatalysis Offers a complete package correlating various aspects of microwaves in organic syntheses, the biological impact of products formed in reactions, pharmacological features, and environmental sustainability of the procedures Explains microwave-induced reactions on structurally complex bile acids and sterols Stands as a valuable and unique addition to the well-established book series, New Directions in Organic and Biological Chemistry

The third edition of the bestselling two-volume reference covers everything you need to know about microwave technology for synthesis - from the best equipment to nonthermal effects, from solid-support reactions to catalysis. Completely revised and updated with half of the authors completely new to the project, this comprehensive work is clearly divided into two parts on the fundamentals of microwave irradiation, and application of microwaves and synergies with other enabling techniques. Also new to this edition are chapters on on-line monitoring, flow chemistry, combination with ultrasounds and natural products, including multicomponent reactions. An indispensable source for organic, catalytic, physical, and medicinal chemists.

Microwave Chemistry has changed the way to work in chemical laboratories and is an established state-of-the-art technology to accelarate and enhance chemical processes. This book not only gives an overview of the technology, its historical development and theoretical background, but also presents its exceptionally broad spectrum of applications. Microwave Chemistry enables graduate students and scientist to learn and apply its methods successfully.

The first reports on the application of microwaves in organic synthesis date back to 1986, but it was not until the recent introduction of specifically designed and constructed equipment, which countered the safety and reproducibility concerns, that synthetic application of microwaves has become established as a laboratory technique. Microwave assisted synthesis is now being adopted in many industrial and academic laboratories to take advantage of the novel chemistry that can be carried out using a variety of organic reaction types. This book demonstrates the underlying principles of microwave dielectric heating and, by reference to a range of organic reaction types, it’s effective use in synthetic organic chemistry. To illustrate the impact microwave assisted organic synthesis can have on chemical research, case studies drawn mainly from the pharmaceutical industry are presented.

For the first time, this comprehensive handbook presents the emerging field of microwave technology for the synthesis of nanoparticles. Divided into three parts--fundamentals, methods, and applications--it covers topics including microwave theory, scale-up, microwave plasma synthesis, characterization, and more. This offers both an important volume for academic researchers, and a resource for those in industry exploring the applications of nanoparticles in semiconductors, electronics, catalysis, sensors, and more.

Magnetic nanocatalysts are becoming an important tool for greener catalytic processes in chemical transformations in view of the ease of their removal from a reaction medium. This book explores assorted magnetic nanocatalysts, their deployment in synthesis, chemical transformation and their recovery and reuse. Various thematic topics embodied include magnetic nanocatalysts for S-S bond formation, N-heterocycle formation, C-heteroatom bond formation, silica-supported catalysts, multicomponent reactions, including their recyclability; another available volume emphasizes the utility of magnetic nanocatalysts in industrial appliances.